Member Info for wyndrum

Pedro answer this please rather than your very boring repetitive response to any sort of debate.

The SP 12 months was 50p, its 55p now.

Where has all (in your observance) the fud been misdirected?

Given the posters you listed have until thorns 180 degree volte face, for the most part have urged caution on funding and the lack of deals with partial data over that period, would it be fair and reasonable to say that they have been broadly correct?

Now i guarantee you won't answer that because you never, ever, ever, defend your position. You just call people names and run away.

And also could you all try beingh abit more accurate please? You can't spread fear unless you are financiallt very over committed in which case thats yopur problem not anyone elses. As for uncertainty and doubt? well... Duh? you have no idea whats going behind the scenes whether financial, deal making or ongoing results from the trial.

So where does your certainty and belief come from which is so more reasonable to express rather than a contrary view?

Again, there will be no answers to any of this because the questions are reasonable and the answers will make the posters look as foolish as they patently seem to be.

Thanks for the reasoned reply Max. All helps to lift the level of discussion here.

Max, I guess its the hyperbole that gets to me here.

Mad? Mad ? The best you can say by waiting for a better price? what about just saying its a risk? And how to calibrate that risk.

Would you have made your statement a couple of weeks jago ust prior to the since 25% drop?

12 months ago the SP was 50p so another 12 months of all this exceeding expectations and new data and rearranged financing etc etc etc, and ....its hardly moved at all. great...

Just accept it for what it is,, a very high risk punt on a bio tech in a market with a greater chance of failure than sucess.

As I say i am not sure the term "mad" applies to cautious posters here.

Merry Christmas and a Happy new year to all.

Apologies to everyone here for this but I wanted to very quickly talk to Dee G.

The better the gear the easier it will be to play and the sound will be better too which may keep the level of interest up so as to increase the chances to make it a life long thing.

(Also should no 1 daughter not stick with it then it will have better resale value then very cheap stuff.)

I love Fenders (esp the Strat) for the sound and iconic looks so the Squeir might be a good choice pricewise. Of course if you really loved her you would get her a proper fender Strat and be done with it ! ha ha) and although i am not a fan per se, Yamaha are very, very good (yamaha pacifica 112v would be a great choice I think for her.)

I don't know here age but the weight of guitars vary. Gibsons for instance are much heavier than the fender range.

Again with quality and value in mind for the Amp, Peavy is a solid respected brand (stay away from Marshall until she has her own band!)

Peavey Vypyr X1 Modelling Amp might look a bit complicated but you just find the sound you want and stick with it. As she gets better then she will naturally want different tones and styles and that amp has them all.

So for less than £500 with probably £200-300 resale then that looks to me a pretty good place to start. And I think if it sticks, then those choices will be good enough for years to come without her feeling the need to upgrade to better gear.

Lastly i think, It is very important she chooses a guitar in the colour she wants as its just like a car. They all do the same thing but, to keep her playing she has got to like/love the look of it so imagination takes over while she's practising. (She can pretend she is her favourite guitarist when she is plonking away!)

(And if you throw in £5k into g4m there is a pretty good chance you will make 15-20% in the coming month(s) when the christmas period is delivered on the 20th and the profit will pay for the outlay so ultimately it will be for free. :0) Obviously thats just my opinion and not financial advice!

Anyway, hope you and the family a lovely break. Fondest regards,

Thanks again everyone here.

All the very best to you and the family particularly your girl xx

Merry Christmas D and I have wanted to ask how your daughter is but its difficult to do these boards.

As for a guitar how much money do you want to spend and is it acoustic or electric?

(We are off to Les Arc late Jan for week so that should be fun!)

I have never professed to being that up to date on pc/internet progression.

Plus all I try to do is make some money trading shares and post my thoughts on these BB's.

Quite why so many of you here have such a poor view of me is beyond me.

It seems to be the assumption that you all think I have the ability to manipulate share prices of stocks that I trade in simply by expressing my views here.

The problem is, if you really believe that then it is you who are pretty stupid.

The other somewhat fantastical assumption is that I prey on the weak here andd convince them to buy or sell on my thought process.

2 things spring from that. Had they done that on this stock they would have made money (heaven forfend) and more realistically, where are these weak souls? Do they never post? Do they quietly lose all their money following other peoples views other than thweir own?

The basis for the animosity is simply not coherent.

I get you don't like what I post or its style or whatever, but the invented reasons to be so abusive are the flimsiest of excuses for your poor reasoning powers.

And a Merry Christmas to you too, Sheppy.

You are completely and utterly wrong in thinking we are all the same poster. That is against LSE "rules" so please ask them and get these multiple log-ins deleted and see what happens.

When nothing happens please have the good grace simply to apologise and move on.

It does not have to stop you being rude and offensive but at least it would stop you looking a bit of a charlie in this regard.

Gem, Its what the market wants or was expecting. I keep saying its great news for those with that cancer however, SGC is a relatively rare and therefore small market. And even then the results have not been uniform.

Please do bear in mind I look at this purely from an investment pov.

I want to know what happened or is happening to the big market treatments which at the begining 6k was meant to test and address. Why the silence?

Typically silence is bad news. If that is the case this time around too, then its not as effective as we incl. avct, hoped.

And there is the dilema Gem, very positive words but less so in the results and the market remains to be convinced.

But the big thing here is time. If the market is right and the next 3-6 months will be fairly baron on result data then the money can go elsewhere to work and come back later.

And thats the thing, I for instance am forever taking out and putting back in AVCt as and when it looks like the risk is worth it. Its not all or nothing, its not a one-off decision to be in or out. Thats the fun of it.

As you can tell Thorn I am not as optimistic as you.

Time is a critical factor and the relatively poor performance of 6k has put the timeline back. Its not been a waste of time but it has not provided the breakthrough we all expected so now its all about another trial soon to be launched. Again that puts results back a year or so and all the time other treatments are being developed. At best i think it devalues the tech to some degree but that is on the assumption that "it works".

I would remind all here, the initial results on the mice in the lab for 6k meant it could not fail... and yet it ultimately disappointed just as every other bit of AVCT tech has to date.

So to expect the next trial to be "The One" does remind me a little bit of the definition of madness......

Pace, I can't predict the future. I don't know whats going to haappen.

I said a few times that 32p was key and when it broke through I bought.

The trouble is, people forget when I called my trades before hand and like to focus only on when i explain what I have already done. (Plus I sold 30k of shares so still hold 20k)

(Also I was repeatedly told at the time a couple of years ago here, to stop telling everyone what I was doing as no one was interested. So It would appear I can't win.)

I have reinvested my sales in part, to a stock that was going to report an income stream for the first time in December in Helium Gas. It duly has and the SP went up.

Its really not so hard to make money if you have the time to monitor the markets and are happy to "risk" being out of a stock and miss the huge rise that always follows when you sell.... (except if you think things through that "risk" can assessed as to how likely surprising, breaking news is to be released.)

It comes across to me that there are at least a few here who think AVCt will be the change in cancer treatment. I have no idea if that going to happen but think it less likely than more.

The research on cancer is vaccines and diet. (its dawning on many that UPF and our diet in general is causing a lot of cancers.) As the research develops into how proteins react in our bodies I am sure we will see quite stunning breakthroughs.

In the mean time that does not mean I can't make money out of trading AVCT but i don't see it in the same light as the rose tinted brigade do. It may well get bought out and maybe for a billion or two or more? How do I know, but it feels to me that is the very best upside and would still represent extremely good returns, but right now I see little evidence that that is coming any time soon. (imo dyor etc)

Gem, the data is poor relative to market expectation. P1a proved safety with no MTD found. It also spent years working out dose frequency and amounts so that when P1b started it would be very very effective and prove concept. "All" that P1b has shown is it has in some cases on an untreatable cancer so no comparison, minor responses. The results were patchy and not uniform and that was after cherry picking the patients.

You tell me, did you expect more from P1b at this stage? If you did, then you are in line with the market. So the SP was walked up expecting something more than it was given so it is walking it back down now.

The other pressure is other stocks to transfer funds to. AVCT is now on the back burner for likely months. Plus you have maybe concerns about future funding, plus it lessens the chance of any license of 6k or at the very least the value of it for at least awhile.

Many here get frustrated with the short term mentality of Aim, as though this was abad thing.

Aim is just a market place to place bets. Why wait 5 years to make 100% if you can do it 1 week or recently with AVCT a few months? So of course money moves around. I honestly don't understand why some posters here get hot under the collar about it. Its always been the ca LTH are for big , profitable companies, not high risk bio techs and the like.

Russ I have already sold, so I am noot emotionally drawn as I am not sitting on a loss.

I have no idea if it will bounce from here fall tom 54p or 43p.

Every day the picture changes, and often intra day.

So i have to constantly monitor events.

Right now I can't see much reason to buy. If I am in the majority then the SP will fall further.

I don't have anything to prove to myself and as for the majority here well, they don't believe me when i do get it right, they just say i lied.

What I try to do is explain why i do the things I do, If anyone sees mmerit in the logic then maybe it is of help.

All I know, is this share just keeps giving (to me), so what do i care?

54p maybe 43p

I know it sounds fuddy but for those that stick their heads in the sand it can be quite expensive.

Forget the science for a moment, the data was poor (relatively) so no deal likel;y coming soon therefore what supports the SP? basically nothing.

So we are back to funding.

This to me was absolutely blindingly obvious. So all those(watching) that say io am preying on the weak, would have done well to listen to me don't you think?

Like I say I am not actually an idiot. I dentifiedd at 32p that it was likely to go up and sold mid seventies.

The idea is to make money NOT fall in love with a share certificate.

Although I am quite resigned to the unfortunate animosity sometimes directed at me nevertheless I do wish you all well and good health, wealth and happiness over the holidays and beyond xx

Ginge, whats the profit on the £1.5b market value? What profit margin do you think BP work on? They are not filthy rich because they are so generous with their money.

Thats why i can't calculate its worth.

I am not in fact an idiot or somebody that just posts FUD as you many here misleadingly post.

This is an investment BB and my experience has taught me to be a bit more hard headed and ask awkward questions.

This is not a zero sum game. Thee are many other growth stocks competing for the finite amount of investor funds.

Chris I have highlighted the success in SGC. I just don't what value AVCT have for that market given its relatively rare occurrence.

This (6k) was meant to go after big market value cancers and it seems to have missed its mark. Do you agree with that?

Max with all due respect i know as much as you do on the tech.

The market for SGC is relatively small. What AVCT have not proven with any data yet that its sufficiently efficacious on treatable cancers.

Whether Thorn is right or not in his reasoning, the fact is safe is ireelivant.

What I don't get is if you can keep taking much more dox than previously, why are we not being shown data huge advances in the tumour destruction?

What happened to older folk being treatable? why aren't in P1b, patients being given it every two weeks for 6 months? You would think 12 higher doses in a shorter time fram would be abit more dramatic accross the board?

Maybe i don't know enough about the science but I do know what AVCT led to me believe and it has not yet performed to expectation. (Anyone here still want to say it has exceeded expectations or are we all going to ignore that and forget all the posters who said it had and is?)

This is hugely complex and it always takes more money and time than we are told. I am still nit sure if AVCT are really onto something commercial yet.

Max, the problem is efficacy is not good enough in the current trial for cancers that are already treatable.

That whether we like it or not, throws doubt as to actually, in fact, how good will the next version/trial be? (We only have CC's word its going to be great and the market takes little notice of that.)

I think we have to factor in time delays as its the nature of the beast. So now its some sort of deal which has not happened yet on 6k so I don't see why now, all of a sudden its on the cards, other than as I say SGC but what is that worth at this stage of P1b?

It feels to me we are back to rabbits and hats time again.