Member Info for wyndrum

Well for all those posters recs, can I ask how their investment has gone?

I have done well with this one as it turns out. (trades pretty reliably).

I just wonder for all the positivity how they square it with the actual results of the company.

I will ask again for posters to comment on when CC said a deal in the not too distant future, how long did you think she meant?

Its important because it goes to the veracity of the utterances of the BoD. I am deluged here with quotes from AVCt but where is the ND listing? Again, did you think it would be here by now given its over a year, I think since it was intimated as a way forward?

Does this follow a pattern with AVCT? ie has it happened on more than one occasion ion the past?

Perhaps all your recs pedo, could be more attuned to actually discussing the likely way forward rather than trying to shut down ideas that might actually help wealth creation as opposed wealth destruction.

Well ok but there are lots of posters here that post "positive " info which, speaking for myself I disagree with on the logic they use to come to their conclusions.

(Also the vast majority of posts are actually insults and deliberate misrepresentation. Perhaps if they gave it a rest the whole board would benefit but I and others have constantly asked for this to see how it would pan out but the disrupters will not do it. That should tell you all you need to know where to direct your frustration, but I do note, you never do.)

Chris its no more being a c... to when in this case there is likely not to be positive news for some time to post it "regularly", as is posting just as regularly that everything is going great guns and ignoring the lack of SP-moving news.

I think too it is more likely to fall than rise going forward until new news is released. There is also a chance (50/50?) there could be a raise first before news.

Is it not fair/wise/prudent for any new members to this BB to be aware of these potential outcomes prior to perhaps buying?

I get that Thompi, but what about the " we are all one poster" classic? Or the "We will not answer any awkward question so we will call it FUD" classic, of the novella of just insults.

The feeling seems to be that it is the posters who see potential pitfalls that are the problem of disrupting the board whereas the posters, watching sheppy Timster, cindecone pedro, mostly BV CJ and many others get a complete free pass for actually causing the disruption.

Its a strange BB where the disrupters are encouraged and the posters who's caution has proved broadly if not completely correct for years, are constantly abused and hounded.

Thorn:

"Lord of the Flies is about a group of British schoolboys stranded on a deserted island who descend into savagery as they fail to govern themselves, exploring themes of human nature, civilization vs. chaos, and the inherent capacity for evil within humanity"

(it was written in the 30's and is a classic that used to be taught in schools.)

So, if its noit the science then what can it be?

I guess that only leaves the funding.

NTF will assure you all that the minimum amount they HAD to raise showed they had "smashed" funding. Hmm, I am not so sure.

The fact is is the SP is 10-15% below the last raise which I think somewhat refutes NFT's logic and reasoning, but then almost everything he has posted recently has not materialised, so I don't think his grip on finance, the market or indeed the science is that firm, suggests to me as it I said some weeks ago, we are back to funding restraining the SP appreciation.

If i am wrong then its the science and the funding.

There is insufficient funds to take the next trial to completion. So it seems a cash injection of some sort is irriftible.

Therefore its either a deal of some sort of a RI (shareholder dilution).

Given the SP fell on the latest remarks of CC then it does not look likely it will be a deal and if it isn't, then how do you square her, "in the nor to distant future" remark?

If as is most likely because there has been no outside cash injection for years and years, it is to be a RI how much do you think will be needed?

Then of course the SP becomes very relevant, as the lower the RI is done so the higher dilution to shareholders.

So for all those that bang on about they have all the time in the world and time does not matter, and the SP does not matter, are with NFT not understanding either finance or the market. (Oh, hold on yes they do because they believe the market is as thick as mince, don't you Tim and the rest)

This post will likely be deleted as that has resurfaced as the best way to silence my opinion. I will be surprised, if it remains, as to how many will actually engage and answer my questions as opposed to simply lying, insults, and simply misquoting me.

If it was all a lot less personal and al ot more collegiate, we would all I think be financially better off on this particular stock.

Imagine a world without the “fudsters” obviously you would lose sheppy and watching too but think of all the constant reinforcement of the positivity you all put so much stock in. I would be amazed if it didn’t lead to more buys here and over commitment.

Still financial ruin is a small price to pay for us moving on

Have I missed anything? NFT’s rns? sp rise? Deal announced? Funding resolved? Any clarification on half life? Rampers proved right? Anything at all from this much heralded meeting to support the Sp?

I ask because there was much discussion and hype about this pivotal meeting of the great and the good.

Seems that you lot may have been wrong (again).

I expect therefore the insults to continue rather than actually discuss this in a more adult way.

I sold at 77.and if it’s not obvious by now I do think that this could still generate good returns.

I tend to keep a certain amount and sold mor at 57 to lock in good profit from the 32p purchase.

I don’t care if I buy back in at 60p or 80p all I focus on is profiting from that new trade.

This works for me. Clearly you want to see a mega one off buy and sell. Well it’s been 5 years. How’s it working out for you?

Intraday moves are relevant to day traders. To extrapolate longer trends you need to look at daily closes.

Right now all I am seeing is that a support is being tested. It remains to be seen who will win. It is impossible to see who is buying and who is selling.

Also volume is not that reliable an indicator.

This could be a bear trap for all we know or it might bounce away from here but a chartist will want more proof that the downtrend has finished so the smart money in the absence of news would wait until maybe 60p has been achieved.

Hi D, just seen your in!

Fingers crossed

(I like Wosg over the next 12 months too)

Well elliot is a real black art, god knows what waves are ever current. :0))

I have never made it work for me. (Whereas the RSI.......)

Each to his own. atb

People are people Ray, And pretty predictable at that, it turns out....

Great break out but further retracement seems likely as the RS indicator is still in over bought territory, probably to around 10.5 to test the support that has now been formed.

If bullish it won't hang around long at 10.5p so for those wanting to get in or top up it might be prudent to keep watch.

Anyway just my opinion, dyor etc etc

Well (fwiw) I think you are going to have a good year in the "safe" stocks Touk.

It looks like there will be over production of oil leading to lower energy prices, lowering inflation, both encouraging investment.

I had taken profit from RR last year but bought back in today and even with the costs am just in profit already.

Luxury goods as well as defence and ironically BP should do well too. Banks might be mixed as interest rates come down but they have already performed well.

Always a chance of market meltdown so I am wary of the high the tech section but who cares, as long as you can clear 15% per annum and compound away it gets very easy.

And of course thats the big risk to an unbalanced portfolio. One TRX can set back the whole portfolio years to recover and for all you kids out there one day, one day, it will dawn on you that the single most valuable commodity is time and it simply can't be wasted on hanging on to poor performing stocks.

AVCT is in sticky territory now (for the record because some care, i sold at 57.83 this morning).

Its right on a minor support having gone through 60p and is just below 57p. given the dramatic fall over the last few weeks it looks more like further falls than bouncing off, but we shall see.

The danger for holders is the big support (which I think will be tested), at 50p. Hopefully it holds otherwise 25p hoves into view. (imo dyor etc etc)

I'll leave it after this but just to clarify:

I am not looking at this as though it was a bed mattress maker. (for gods sake). Its a different company in a different market. There is no evidence whatsoever to support your claim that the market is overlaying this sale to Merke you keep referring to. (The SP has fallen 10% just this morning).

I never said that Tempus was a holder in AVCT, YOU DID!

and not for nothing your poor understanding of words is what is causing these posts:

"No, collaboration isn't the same as being a partner; collaboration is broader and can be informal, focusing on shared goals for a project, while a partnership implies a more formal, structured, often legally bound relationship with shared ownership, risks, and rewards. Collaboration is about working together to create something greater, with looser ties, whereas partnership suggests deeper commitment, shared resources, and potential hierarchy or joint financial responsibility, often detailed in contracts. "

The "platform" may be de-risked inasmuch as it keeps DOX away from the bloodstream. I am not convinced that by doing so it has not also inhibited some of Dox's therapeutic attributes at the same time. (If that is so, if mind, then the "platform" is greatly reduced in value. The next trial aims to combat that possibility.

I would remind you the latest borrowing/funding (but not the last I fear) was only for a further 6 months on what was available in their cash runway and was part of a guarantee that heights demanded for suspending repayment and would not lose out.

So to say they "smashed" it I think is up to you to use that word but given its very much a temporary bridge I don't see it in such a positive light.

My feeling at the time was that it bought time for AVCT to show the efficacy of P1b and to do this "not-too-distant- future deal. Since that data release the shares have collapsed (again) and it looks to me that it puts funding back in the spotlight as there will not likely be too much new data for the market given the next trial does not even start for another couple of months let alone be able to show prelim. results.

"Tempus AI, Inc. is not a known stockholder in Avacta Group Plc. The companies are independent entities that entered into a strategic collaboration in October 2024 to advance AI-driven cancer drug development. Collaboration, not ownership: Avacta (AIM: AVCT) and Tempus (NASDAQ: TEM) formed a strategic partnership. Avacta gains access to Tempus' extensive datasets of tumor samples and clinical data to support its pre|CISION® technology development, but this does not involve Tempus taking an equity stake in Avacta.

Purpose: The collaboration is designed to use artificial intelligence and large datasets to help Avacta identify broader patient populations for its clinical programs and optimize its drug development process."

Quoting accurately and not misrepresenting me, is NOT playing word games. Whereas you, ARE playing free and loose with words and assuming that because several companies have been bought out for high amounts (albeit in some cases much further along than AVCT), that it is inevitable that that value should be transposed to AVCT although you don't know intimately the details of either AVCT's tech and results or indeed the companies that have been bought.

My position has been that the tech is promising and if it works should deliver exceptional gains to the investor. However I see failure more likely than success because not only of the high rate of these companies failing but the difficulty in raising funds when the data is not available to be conclusive.

To date an unbiased look at the history of AVCT would confirm that it is find success elusive.

Ok, here we go again:

Disease Control Rate (DCR) is a clinical trial metric, primarily in oncology, that measures the percentage of patients whose cancer either shrinks (Partial Response - PR), disappears (Complete Response - CR), or stops growing/stays the same size (Stable Disease - SD) after treatment, calculated as CR + PR + SD / Total Patients. It's useful for evaluating drugs that primarily slow cancer (tumoristatic) rather than kill it, but can sometimes exaggerate a therapy's true benefit, as it includes stable disease which might not always mean significant clinical improvement.

While the heart is being protected there are still (much reduced) side effects which is why I queried the "zero" claim you made.

You then go on to actually quote what I posted which is nothing like what you initially "said" I said. Surely even you can read it back and see where you have been grossly misleading.

". The "Why 3 Extra Cohorts?" Question

• The Answer: Because no MTD (Maximum Tolerated Dose) was reached.

And has an MTD been found yet? so why was the P1a halted and not continued? At the very begining of the trial AS said he did not expect an MTD to be found, so why did they insist it carrying on? By best guess is that it was not delivering enough expected harm to the tumour itself and hoped that by increasing it further it would at some stage overwhelm the cancerous cells, but this does not seem to have been the case.

As has been said previously, its a moot point for it to be safe if it is not as effective as standard Dox. There is so much we don't know.

And by the way, why didnt the other 3 (10%) of the patients have any response at all? It suggests (to me) this is all a bit more complex than you seem to give it credit for.

"The Jan 20th "cliff" he predicted is already a memory. The Q1 2026 breakout is the reality."

How can the future be a reality? (Stupid remark) The actuality of 2026 is flat after falling 25% in the previous 30 days when all the latest info was available. (Explain that!)

And again what quote regarding a "cliff" are you referring to? Please show me the context of that supposed quote you have implied I made

Your definition of commercial is utterly ridiculous and you continue to display your inability to either defend your assertions (that you imply are facts but are nothing of the sort), and your deliberate attempt to evade the FACT that in 20 years and £200m ish of attempts not only has every strand of AVCT tech failed to make the company cash positive but that have also sold every assett they can to stay in business.

They do not have many TR1 holders or big investors. On just about every metric AVCT screams "High risk.

Now, some of you may say, yeah I know, but thats not the argument being put forward by NFT. He is saying its a done deal with the new trial although it has not started yet. P1 has been a complete success and that funding is not an issue because of the positional financial strength of the company.

I don't see it that way.