Member Info for RayPointer

Yes, I know.
And hopefully the recent modest daily rises are just a small taste of things to come.

Yes indeed C7. There are a confusing set of peaks around about this level in the 1 year chart.
It would be nice to clear those first.

aren't we at the resistance point we have met before?

How representative of the general population are 100 fishermen on a boat?
It's not exactly a sedentary occupation and what is the average age?
If you replaced the fishermen with people from care homes what would the results be?
Mind you, you probably wouldn't catch many fish :-)

Low cost funeral though :-)

It would be just our luck that Scancell announce their mega deal the day before the red giant absorbs us all.

" Ruck or anyone else believes it. i.e. on the equator the sun will rise every morning and set every evening until the end of time"

I am afraid not. The sun will eventually become a red giant and earth will get absorbed along with mercury and venus.
Don't worry it will only happen after about 7 or 8 billion years.

Inan is now surrounded by eminent mathematicians with calculators of deadly accuracy.
Will he be captured and tortured until he gives up the magic £8 formula?
Stay tuned for the latest developments.

Hi Bunsie

The BOD could try to slow Lindy down but I doubt they would have any success.
She reads too many articles and then has ideas.
Mind you, with Poundland Biotech, somebody else does the hard graft while Lindy supervises.

The more discoveries the better IMO.
Remember, once LD is happy with her research she hands it over to Sally's team for development.

Lindy's current pipeline of research

Covidity
Modi2
Modi3?
? (other light bulb moments)

It might also be the new tear gas for Hong Kong protesters.

Who is JP?
I meant JC

different audiences

Lindy talks to her scientific peers
Cliff talks to PIs at proactive events
Cliff and maybe JP/RG also talk to IIs separately - hence Vulpes and Redmile are investors
Cliff and again maybe JP/RG also talk to pharmas about deals

The talking will no doubt continue on all 4 fronts and hopefully a pile of cash will come our way soon.

of course there is nothing stopping Cliff from conducting a zoom meeting on his mobile whilst doing the proactive presentation :-)

https://www.scancell.co.uk/Data/Sites/1/media/docspres/presentation-to-lsx-world-congress-february-2020.pdf

Slide 17 of this recent presentation is a good summary of the 5 glycans mabs.
On top of that you have the concept of Avidimab that can be applied to any mab.

Also note that mab2811 has the potential to expand the population of TSCMs in order to attack a solid tumour of your choice as long as it recognises the particular TCR of the TSCM. This could be effected by the TSCM expansion itself or via TCR or via Car-T.

As I understand it, mab2811 has a very different concept to the other glycans mabs.
It targets TSCMs to stimulate expansion rather than attacking the tumour. Hence at the Paris conference it had its own poster.
It may be treated separately if and when it comes to a deal.
There are so many permutations for a possible deal so we could have a prolonged set of talks.

Crumbs, you mentioned the "D" word

https://www.youtube.com/watch?v=yfl6Lu3xQW0

I hope you get away with it.

Even better, the effect lasts for months.
At least the memory does.

No problem Chester.

If Pfizer buy it, it could be branded Viagramab.

Just the normal run of the mill conclusions for Mab2811

From the poster again:

Conclusions

1) SSEA-4 is a novel marker for human and mouse TSCMs.
2) 2811 mAb able to identify, isolate and expand putative TSCM in vitro and in vivo.
3) 2811+ T cells are potential candidates for genetic manipulation to express antigen specific TCRs or CARs.
4) 2811 is a potential T cell agonistic mAb

Number 3) may have been noticed by Biontech amongst others.

But be careful, Supermab may be weakened by green kyrptonite :-)