Member Info for RayPointer

Burble

I think they mean both.
It has the high avidity and aIso the potential to attach the killing agent to the Fc region. It's a delivery mechanism as well.

Surely Avidimab will have great potential in mABs against viral infections as well as cancer.

Violin, I hope you recovered fully from Covid19.
You've really had a rough time of it lately.
ATB and I hope this is the end of your woes.

and Mr Bean is doing well as a doctor

https://www.youtube.com/watch?v=vFDSWuffBcA

I hope CH has been working out during lockdown

The point is that Lindy may well have found the best possible cancer targets.
Time will tell.

Morning Ruck
It is interesting that Sarah Gilbert was involved in the universal flu vaccine. This produces
T Cells that target a core protein rather than producing antibodies.

https://en.m.wikipedia.org/wiki/Sarah_Gilbert

I would have thought that the best combination of T Cells plus neutralizing antibodies thrown in for good measure would stand a chance.

Ruck
Do you assign zero value to the increased IP?

IMO, it is obvious that Lindy has a number of ideas that she still hasn't progressed.
What will come after Modi1 and Modi2.

She has already stated that she is excited about the combination of Modi1 and Modi2. But once Modi2 is in development, the bulk of the research of this combo could quite easily be carried out by members of Lindy's team with Lindy just acting as supervisor.
For a given cancer, the relative levels of expression of citrullinated and homocitrullinated proteins may vary from patient to patient, so combining the 2 vaccines could cast the net wider.

Modi3 could then be next in line for the Lindy treatment.

Perhaps Nottingham Uni have demoted Lindy. Drunk in charge of an electron microscope.
Or is it Dr Dilly he is talking about?

Nom

Who is Dr D?
Are you posting on the wrong board my mistake?

I would hate Norfolk to go into lockdown due to the amount of oil on the road

Here's the abstract of the original Nature article on which the tweet is based.

https://www.nature.com/articles/s41586-020-2550-z

The final sentence

"Understanding how pre-existing NP- and ORF-1-specific T cells present in the general population impact susceptibility and pathogenesis of SARS-CoV-2 infection is of paramount importance for the management of the current COVID-19 pandemic."

Is this the one Rats?

https://twitter.com/megtirrell/status/1288102322141384705

Common N protein?

Yes, I know.
We may end up with bucks fizz.

I think the orange juice debate should be split into two.
The orange juice debate should remain as a debate about the definition of dilution. Gold miners to that debate.
The new debate "champagne" should debate how an extra 15 mill together with a new investor will help Scancell achieve their goals and to what extent.

Chester

It did seem to stun the B&B into silence.
I will try it again if and when the "orange juice" debate resumes.

Gold miners?

There may have been times when the BOD would have considered a takeover as a good option but I don't think now is one of those times.
Funding for 2+ years, distinct possibilities of deals, possibility of Covidity funding, trials to look forward to (we hope).
I would think Lindy is quite happy right now.