Trying to do a Poirot30 Jul 2021 13:11
Inspired by learning that the Spanish for leak is Perdita, I wondered what our old Mass Spectrometry friend Perdita Barran was up to these days. I put Perdita Barran and Avacta into Google and came up with this....
https://theanalyticalscientist.com/fileadmin/tas/pdf-versions/issues/0321_TAS_Issue.pdf
Where, on page 7 we find this news in brief...
Avacta Group and Bruker Corporation have entered into an agreement to evaluate the Adeptrix coronavirus antigen test, which is based on bead-assisted MS. This represents an exciting step towards implementing this high-throughput test in typical clinical microbiology lab workflows.
Then on page 24 is a feature on Perdita Barran talking about how mass spectrometry is potentially much better than PCR for Covid testing:
What is interesting to me in this area at the moment is comparing the abundance of viral protein (as found by MS) to viral RNA (as detected by RT-PCR). It may be that the viral protein abundance is a better indication of infectivity, as there are lots of reports of RNA hanging around much longer than an individual is infectious.
The other role for targeted MS will be to determine the presence of mutations in the virus. This diagnostic capacity could be extremely helpful in surveillance testing, as we will need to know if the vaccine continues to provide immunity – especially as new strains emerge.
Not quite sure what it all means, but it still sounds as though there's still plenty of potential in the MS field.