RE: AACR LAST YEAR 202310 Mar 2024 14:51
CT, I understand, but it has not stopped AS remarking on the efficacy benefits in other individual patients.
So I take your point entirely re large scale extrapolation, but he could have made some qualified remark in what had been observed with these quite remarkable dosages of Dox.
Now the dust has settled I find it more likely that it was a designed strategy to get funding from ii's at a level they gain sufficient reward for the risk.
The only downside I see from this is that a potential TO may be quite a bit less then we were all dreaming of not so long ago. But that is quite a few assumptions I ma making and building on each one. But that is where my present thinking is taking me.
Its starting to make sense to me in other areas too.
(more assumptions coming.)
Maybe AS knew more funding was going to be needed to get to the end of the trial in September, so talked up pardigim shift etc, to increase the SP to help in raising max funds, but with the best of intentions, the II's were having none of it.
So he has had to eat quite a lot of humble pie in the intervening period. That would explain why as usual they get the lions share of the opportunity. The "good" news, is perhaps, now we are in a period where the hyperbole can go on the back burner and they just give accurate updates. The interview with Paul Hill, or whoever will be (for me) the first test.
Release the data without unambigious statements.
Its that or presumably.. no future for AS?