RE: Further proof8 Mar 2021 09:14
FinnCap, 310 or 796, 3 x looking easy! Lol!
Lateral flow test can detect Kent variant of SARS-CoV-2
Confirmation that Avacta’s AffiDX® SARS Co-V-2 rapid antigen lateral flow test can detect the dominant mutated variants of the SARS CoV-2 virus is clearly a positive message for investors as it does not undermine the current test format, for which we await final clinical validation and CE marking around the end of the month. It is not unsurprising, given the Affimers in the tests do not bind in the region of the spike protein where the dominant mutations appear, but nevertheless, is reassuring. The ability to use the current test format to ‘plug and play’ new Affimer reagents for new variants, if necessary, as well as for any future pandemic virus, provides a lateral flow test format of long-term value. We reiterate our SOTP target price of 310p.
?Newsflow. AffiDX® SARS-CoV-2 rapid antigen lateral flow test has been shown to detect the dominant new variants of the coronavirus. This includes (i) the B117 or Kent variant, which is the dominant form in the UK, present in over 50 countries and expected to become the next dominant strain globally, (ii) the D614G variant (commonly referred to as the G variant), which became the dominant global strain in 2020, as well as (iii) the original Wuhan strain.
?Implications. The fact that Avacta’s test can detect these dominant mutating strains of SARS-CoV-2 is clearly relevant as it suggests that (i) the test is less likely to be obsoleted as additional variants are identified and (ii) the test performance as determined by the current ongoing clinical evaluation is also unlikely to be affected. Equally, the lateral flow test architecture and strip format that has been developed by Avacta and its partners is sufficiently robust to ‘plug and play’ new Affimer reagents for new variants, if necessary, as well as for any future pandemic virus.
?Near-term outlook. We await full clinical validation and CE marking of the lateral flow antigen test around the end of Q1 2021, having already seen positive initial data from anterior nasal swab samples (30 positive samples with an infectious viral load and 26 negative samples), which demonstrated a sensitivity of 96.7% and a specificity of 100%.
?Valuation. No changes to forecasts and we reiterate our SOTP target price of 310p, with a high/low valuation of 796p and 211p, respectively, which reflects different assumptions for its SARS-CoV-2 antigen tests.
Trek