Member Info for ratcliffewriter

It would have been nice to have had that information earlier, but at least it would seem the logjam has now been removed and the trial can get going.

Looking at it another way, if scancell's experience with the trigrid device had been a disaster you can be pretty sure AZ would have been aware as at the very least it would be in Ichor's records from the trial. Therefore it is logical to assume AZ would be aware of its successful use by Scancell too. Imo it stands to reason really.

You'll never win the school spelling competition now C7. Not with the judge being as pedantic and hawkeyed as he is.

I think I understand what you mean - I'm looking at it that LD hasn't just got a vaccine in SCIB1 that does in reality what it was technically meant to do in the lab, but she has understood and designed the entire treatment regime, identifying electroporation as the best way to administer the treatment at the time. (Cynics need only look at the swimmer chart to understand its success) The fact she is now proposing nanoparticles for SCIB2 says to me that electroporation may well be being overtaken by a more practical and more effective method of administration in which LD has had a pivotal role in building it into the project. For me, that's proof of just how much of an all-round grasp of the subject LD has, and the fact AZ are now picking up on electroporation may show that where LD leads, they follow. Good to see a pharma giant following the treatment regime of Scancell, and only 7 years late...!

Very bad form, but hardly a huge surprise. Miniature versions is such antics are attempted regularly from what I've noticed.

I find it a little sad that a poster can have all of their views listened to, debated and addressed, but who then avoids any specific question in relation to points they have raised and then finally signs off with a blanket insult to all those who have provided informed opinions and some very good links to facts well worth knowing or revisiting. It really looks as if the aim was to try to attract some personal slight to use as fodder in an 'I am a victim' campaign, which has manifestly failed, I'm pleased to say. Posters here have been accused of saying 'buy buy buy' which has never been shown to be the case, and the accusations of concerted ramping have been shown to be false. From this weekend's posts there has been shown a great degree of well-founded optimism and confidence (that is not ramping - there is a massive difference) in the progress of scancell, some of it not always at the pace expected, but all of it very much at the leading edge of related scientific developments. This can easily be seen with a bit of research into the wider general state of immunotherapy. The facts from both the scientific and the financial aspects are pretty clear, and it is from that that one makes a decision to buy sell or hold. I think that is as clear as ever, despite poor attempts from a lonely quarter to promote otherwise. Thanks to all for a very useful series of posts over the weekend.

'Ignore/insult - upto you.' Do you not prefer fact-filled dialogue like you had today? It was much more pleasant I thought. Apart from the bit where you accused GF123 and Inanaco of being the same person. That was a bit insulting. Maybe you could start by apologising for that and then you might find you are taken a little more seriously. I think we are all agreed on that anyway.

Be honest Knowlesi, you're just being deliberately obtuse to try to cause an argument.

Agreed C7, but one's approach to investing can be tainted by personal experience, for instance a previous catastrophically bad piece of judgement could affect perception of subsequent companies you look at. An objective view can be difficult to recover.

Inan - I'm guessing you'll have a long wait for any reply using scientific facts to try to counter your post.

It will (or I hope it will) be interesting to see what develops from the trades you have followed these last couple of weeks. Thanks again for the commentary C7. Much valued by me and I think quite a few others.

I have to admit I find it tragically amusing how some folk view the running of the company - When RG was in charge there was an endless stream of bleatings that he was 'the weakest link' and had to go, despite the evident networking and development he was doing. It was he who connected with Keith Flaherty after all - but when does that get any mention of credit? Anyway, then along came John Chiplin to a fanfare of wisdom from the same people, 'excellent choice, he's the man etc etc', as if JC was going to get things sorted in weeks, if not days. Then before he could be slated too much, along came Cliff Holloway, who was greeted as exactly what was needed, presumably expected to 'deliver' in days if not hours. Now the bleatings are turned on him, and another wave of 'he's got to go' is presumably being stirred up. Martin Diggle is now the next to be hailed as 'the man', but presumably if he became CEO it would only take a few weeks before the whining would start again and they'd want yet another change. Anything to cause instability it seems - but significantly with no reference to what has progressed in the last few years, and what the evolution of the management has supervised. It's like building a house and sacking the builder because your mate says the decorators should be working by now, but in actual fact the plasterer hasn't put the skim on the walls yet. I suspect the bleaters would sack the builder and then sit smugly in the pub saying how useless the decorator was because he couldn't get the wallpaper to stay on because the pasterer left before he'd done a decent bit of preparation. For sure everyone wants the trial to start (it will) and everyone wants the IND to be granted (it will) and everyone wants a mega deal and a high share price - will it come? It will imo if the groundwork is good enough, the preparation is thorough, and the science is good. Strange how none of the bleaters slate LD, and yet they could argue she is the one who should work faster - but you can't hurry precision, and it is after all the science, not slick PR that will govern whether or not this is a success.

Why not split the difference at 'reasonably soon, all being well'?

I doubt I'm alone in this C7, but while you may feel like a lone voice in the desert, it is actually very useful and interesting to read your observations and commentary through the day. Basically please keep it up!

5.33 ?!?!

I remember the first time I got a dose. That was quite a memorable occasion too.

Back to 8.20-9.00. Hey ho!

The IND has been so long delayed that I am quite pragmatic about it (no choice anyway really!) so it will come when it comes, but every day will bring it closer, and one day we will wake up to an RNS telling us it has been granted. That will be a fun day I imagine.
I take your point about the existence of a seller feeding the shares into the recent rise, but I am greatly intrigued by the fact that whatever access to shares, the buys keep putting upward pressure on the price - given the apparent shift in sentiment lately to a more realistic (imo) direction I trust we will see this readjustment continue into something that properly reflects the developments and progress made since the sp was in the mid to high teens (and everyone was thinking THAT was low!)

Chester I agree - sentiment and expectation of visible progress are much greater, and this week looks to have been a pause rather than a retrace. Those in profit from the lower single figures (me included I'm pleased to say) show no sign of cashing in I any meaningful quantities, so 10p looks more of a psychological hurdle than a substantial sp barrier imo.

I wasn't surprised to see some profit taking, and would have been very happy to finish in the 8s, so was very pleased to see the rise this afternoon and the size of the odd trade. Bodes well for next week imo. News will come when it comes!