Member Info for MysticMike

Thanks CauldStream7, luckily for me the NHS and my Oncology team have worked really fast from the start until now I cannot praise them enough. I just wish Imm were as good. I agree health is more important than money but I don't like being taken for a ride, I just wish Tim McC actually did care about shareholders and patients waiting for an alternative treatment for Lupus. Does anyone know what happened to Sol the sun cream lotion which was going to take the market by storm?

CS and Wildbunch, l totally ageee with your comments it’s just my battle with cancer is my priority at the moment and on bad days I need to release frustration with Tim McC. He may be the one being used by Avion here and the stating the truth would not help the share price if he said H1 or Q1 of 2024. I just need to forget and hope I’m around to see and appreciate the benefits of my investment.

Come Tim wakey wakey you only have 4 weeks left of H2 nothing will be announced from the 24th Dec until Early in Jan24 (H1). Why do keep letting us down, my only thought is you either enjoy letting us down or you are just have the ability to deliver nothing but broken promises.

Wakey wakey Tim McC you need to come out of your hibernation and make some more u realistic promiseswell extremely vague ones like you are very good at. I hope H2is not going to be like HS2 and scrapped! Im trying to think what you can promise us that would help shareholders an early retirement due to the large savings you have been able to make due to your large salary over the years would be nice and welcomed.

Great discussion and points made i like most long term shareholders who are frustrated and had hoped to take some profit out by now, especially after taking early retirement and investing a part of my tax free pension in Immupharma. The big spanner in my plans has been a sudden health issue that could cut short my retirement and i now need to replan what to do next, so that is my frustration I believe Lupuzor will be successful but if takes any longer the market share will be a lot smaller as there others who putting out other Lupus drugs and alternative remedies.

Wildbunch

I believe they have lied and mislead us they are concerned about thedrug and this is why they keep going backand forth to the FDAfor guidance, they agreed this deal on the 28th November 2019 and I know we have had covid in the middle of it but they have been very economical with the truth and are reluctant to give us regular updates eg the planned timelines and the proposed plan of roll out.

Just another crumb given to shareholders, the BoD and Avion must be getting tired of lying and spinning so many yarns.

Come on Avion pull your finger out we cannot rely on Imm anymore.

As you can all see so much has happened in 12 months or as Tim likes to now say H1 & H2 of 2023

11 Nov 2022 07:31

RNS Number : 1192G

Immupharma PLC

11 November 2022

11 November 2022

ImmuPharma PLC

("ImmuPharma" or the "Company")

Avion confirms its continued support to the Lupuzor™ clinical program in Lupus

whilst exploring broader collaboration opportunities

ImmuPharma PLC (LSE:IMM), the specialist drug discovery and development company, is pleased to update the market on a recent meeting in Atlanta, USA with our US partner, Avion Pharmaceuticals, LLC ("Avion") for strategic discussions around ImmuPharma's Lupuzor™ clinical program.

This included Avion continuing its support to the clinical program of Lupuzor™ for Lupus, as well as a wider discussion on how the two companies could potentially further collaborate.

Key highlights:

· Lupuzor™ for Lupus clinical program to be redesigned on key protocols following written response from FDA, in order to enhance the probability of success.

· Potential of product sales revenues for ImmuPharma by introducing certain Avion drugs into the European market.

Lupuzor™ for Lupus

At the recent meeting in Atlanta, Avion confirmed its support for the Lupuzor™ clinical program in Lupus. This follows on from the receipt in September of the written response from the Food and Drug Administration ("FDA") to the Type C meeting.

In its written response, the FDA provided significant and extremely valuable guidance on the study protocol, that could be amended, to improve the regulatory outcome. This primarily focussed on a recommendation to explore higher dosing levels (given the robust safety profile of Lupuzor™) than have been used in the clinical program to date, to enhance the probability of meeting the primary endpoint of statistically significant efficacy. The ImmuPharma/Avion team, together with external advisors, are preparing a proposed updated clinical programme. This is considering either a Phase 2 dose ranging study to identify the optimum dose level, followed by a Phase 3 study with that optimum dose; or alternatively a Phase 2/3 adaptive study which would encompass the same dose ranging, albeit within one continuous study. The chosen route will be agreed with the FDA. Further details on the study design and progress of the program will be communicated to the market once the FDA has been consulted and their response has been provided.

Potential Distribution Agreement

We have agreed to explore the opportunity of a mutually beneficial route to allow ImmuPharma to introduce certain Avion products into the European market. If this is successful, this would generate top-line product sales revenue for the first time in ImmuPharma's history and contribute net positive cash flow to the Company.

We in turn, have identified an established European partner who could provide the infrastruct

Pokerchips,

I believe both Imm and Avion have blatantly lied and deceived all shareholders and H2 was so vague, if they get any slower

Planning and communicating we will be in 2025 as I've said pre iuosly their last proper RNS was June 2022 and we are now Nov 2023 and all we know is the CRO has been chosen no plan communicated.

Lambo222 I would contact Tim until the end of the month as he's still in hibernation and won't awake until he can start to open his advent calender. I wonder what excuses he will come up with for the delay and the lack of comms in H2 which should have been a ery busy time for Immupharma. They have hidden behind the FDA for too long now and should be delivering value to shareholders Tim must go if there is a delay again.

This was my post on the 15 Dec 2022, and we are nearly a month away from the anniversary of it and we are still in the dark over whether Lupazor will ever get to market or even through a trial with Imm involved. If this is what Tim keeps promising about more frequent comms then as shareholders we don't stand a chance of seeing our investments returning any profit.

Don't Tim and Art want to help Lupus sufferers or are they not truly convinced about the drug anymore?

Question are these comments by Tim and Art back in June the most misleading and worst comments they have made this year? If you think yes click on the recommend below.

RNS: RELEASE 27 JUNE 2022

Commenting on the announcement, Tim McCarthy, Chief Executive Officer, said: "This final step by Avion is a pivotal moment for the Company and for the progress of Lupuzor™ towards becoming a groundbreaking new treatment for Lupus patients. Lupuzor's™ unique mechanism of action and robust safety profile will, we believe, position Lupuzor™ as a first line therapy to many Lupus sufferers globally."

Art Deas, Chief Executive Officer of Avion further commented: "Having met all the FDA's requirements, we are delighted to be seeking the FDA's final guidance on moving Lupuzor™ forward into the new international Phase 3 trial. We anticipate Lupuzor™ becoming the leading product in our portfolio and that it will be instrumental in bringing an innovative treatment to Lupus patients, which is not currently available on the market today."

Lambo

You should know by now that Tim either exaggerates on dates or keeps things from us regarding the FDA. We should all know by now that we can only trust Tim as far as we can throw him. He's a wheeler dealer and has never delivered on anything apart from reducing the share price and losing money for long term shareholders, we just have to hope the medicine delivers what the scientists promise.

Tim does not come out of his hibernation until the second or third week of November, so we just need to wait until then as we all know H2 last until the 31st of December so he could wait until just before Xmas thinking he’s given us all a Xmas present with an announcement that it’s started but patients won’t be selected until Q1 of 2024 and trial starting Q2.

Blue apple it should be 100 times more value but Immupharma and Tim McC always over promise and never deIiver. In 2018 we were told by Tim that signing up with Avion was going to push us on over the next 2 years it did not happen, the SP back then was almost 14 times what it is now. In Tim's book long term is 10 years of a large salary and pension pot for him.

He never give informative target dates its H2 rather than Q4 and now his latest promise is I quote "the next period" is that 3, 6, 9 or 12 months or years or decades. Basically he does not know and he does not know how to deliver anything positive.

This must be the weirdest, odd or bizarre acquisition ever by Mr C. I don't know if he was in Vegas going a few parties and while tanked up he offered to buy the company from someone or its all to do with them having licences in the US. Can someone else shed so light?

Robbie I agree with most of what you say but is it a great buying opportunity as the SP has dropped considerably year on year. That is why my 4 year investment is down overall 58% and I feel like a long term hostage rather than a shareholder.

Ocelot, George said the same in last years half year report but the truth is from last year the SP is down over 36% so he's not really looking after shareholders and his progress is extremely slow and worrying. He knows that shareholders are tied in because selling up now would mean large loses for most long term shareholders, I'm down 58% on my long term investment so I cannot just sell up and get out. I wish he could be honest with us for once and not keep over promising and under delivering.

Good RNS update apart from the last sentence of Tim's comment - "We also continue to concentrate on further commercial and partnering opportunities and with these new Board appointments believe this may be accelerated over the next period."

When does the "next period" start and finish? Come on Tim read back your comment before you put it out and say to yourself would I be happy with such wishy washy timeline.

And the good news from Tim Mc is he's worth every penny of his salary and he's doing a great job for us shareholders. I would like to live in his world, he's obviously thick skinned and happy with mediocre.

If anyone close to Tim Mc monitors this board can you please ask Tim Mc to pull his finger out and give us an update on planning or when we can expect trials to start. I don't think he fully appreciates how much value on our investments if we are long term shareholders that we have, mine is down 75% and now I'm retired I don't have a work income that I can invest more and reduce my average. He keeps telling us he cares and will communicate more but neither are being evidenced.

Even if once a month the update says we are 50% through our planning phase or we are looking to start in September or October telling us he wants to start as quickly as possible is rubbish, Tim please give us something concrete if you don't my 75% will soon become 80% and depress me even more, I'm not in a position to get out and dont want this to be my children's inheritance i would like it to be my enjoyable retirement.