Iovance boosting Proleukin1 Jun 2020 22:24
Clinigen Group PLC (LON:CLIN) shares climbed higher as investors and analysts saw positive read-across from trial data published overnight by Iovance Biotherapeutics Inc (NASDAQ:IOVA).
The US biotech reported interim data from 'cohort 4' of its pivotal phase-two study, where tests of its lifileucel treatment in melanoma met high expectations.
Lifileucel, a tumour infiltrating lymphocyte (TIL) therapy, delivered a 32% overall response rate, effectively matching the response shown in an earlier study.
Every full course of lifileucel requires about six doses of metastatic melanoma drug Proleukin, where Clinigen owns global rights.
Analysts at broker Liberum said the expectations for the pivotal P2 study were high and due to the implications for Clinigen's Proleukin, they have further upped their forecasts and share price target.
“This data looks considerably better than the current approved therapies and while there is still some more data to come, gives us confidence that the product will gain US approval in 2021.”