PYX Resources: Achieving volume and diversification milestones. Watch the video here.
It's the nomads judgment as to whether this is new from a materiality standpoint. There will be nuances to the definition. Personally I'm far more interested in what we've been told Vs when we've been told compared to other people who will have a very slow process and are vital to the growth of the SP.
Yep, out today.
BITL, don't abuse him but asking to explain things he doesn't understand the implications of
The patient must have children that they would otherwise have never gotten to see. And maybe a parent that they are caring for.
I agree, and as an analog more people can be interested.
That's your opinion. There will be nuances to the definition of material that it is up to the nomad to understand and justify if needed.
I recently worked on some regulatory reporting, there is a definition of optional used. This was taken to mean you don't have to fill it in. What they actually mean is conditional. So the regulatory definition of words might be subtly different to the colloquial definition.
I think it's important to remember that the 3996 is an analog to velcade, so whilst it's great that it's dropping it's payload precisely, that payload will have a longer and harder approval journey than 6000 as it's not just a delivery mechanism. Unless that analog is already approved or in process of getting approved.
It'll be out and better than 50:1 tumour to blood
Any evidence for that?
What did you expect, II's running out of the room before it's finished shouting buy-buy? Even if they had of done that what would we have heard?, practically nothing as to buy in volume would take several days to work the orders through. And that precludes NDAs and agreements not to act until later.
I lost 50% in lloyds where there was practically zero upside (It was my early days I liked the divi idea), it's not a small company thing, it's a risk management thing. I went too far in on this, but I coupled that with ignoring the warning signs. The penultimate presentation (I think) he looked so f*cked, I actually thought about selling, but most of the damage had been done, my thought process was 'what's the point, I'd may as well leave it' 3-4 days later it was gone. The financial deals could I have forseen the damage they would cause, probably not.
I could run a sweepstake every day on when complaints of abuse happen.
They do fund him too.. Probably pay for the privilege and don't realise that's not how jobs work.
A level that provides a therapeutic benefit, you know like a medicine does, I would argue for it to be stated like that it should be at least as much as std dox, which with much reduced side effects and no cardiotoxicity is better than std dox.
As to the number, a ratio between blood and tumour i can see how it can be very high, but it's the effect of a level that's useful for treatment with low side effects that's actually important. What I think the number should be is irrelevant.
Neither of which would have therapeutically useful levels of dox. Both at the same time is the key.
So what's your point? I assume you can cope with managing 2 or more pieces of information at the same time.
I guess it's waaaahhh they are lying first then. Next well be, not as good as my imaginary experience said it would be.
No cardio toxicity is out performing dox, lower effects is out performing dox, whilst maintaining a therapeutically useful amount of dox where it's needed.
There are many aspects to performance all of which we have been told are at, or exceeded dox. Ie it's able to apply enough dox, with lower side effects.
Waaahhh, but what if they are lying. Like they've a track record of pushing product that didn't... oh wait no they pulled that of their own accord when the virus mutated.
OK, waaahhhh, what if it's not as good as I've decided, with my lack of medical and oncological experience, it should be. All based on no knowledge, just a thought that 15x should be not as good as 20x, but with no real idea that 10x might be perfectly sufficient to blast away the stroma and allow the dox to hit the tumour and the immune system to do it's job now it's exposed. And then you do it again as that layer regrows.
That's what we'll hear next week, 'I thought it would be..', 'they said previously it was better than this... ' (no they probably didn't' )
It'll be like the sewage filled waters of any modern river with a UK water company.
Touk, are you sure you're looking at the right avacta?
It's been said, I have no proof, that the half life of dox is about 5mins, it's rapidly absorbed or processed, for Ava it's meant to be 4.5 hours, so it's stable, it isn't absorbed except where it is cleaved. This is a good thing, it goes round and round in the bloodstream through kidneys and the liver and back out again, and every time it passes through the tumour some of it cleaves. Constantly hitting it over a sustained period. This is no bad thing.