Member Info for Wildforce

I imagine it’s not simple satisfying the fda !! Especially as Ichor Medical Systems don’t physically make the units .. they are manufactured by Flex (formally Flextronics) so there will be plenty of meetings involved for sure !

Also .. one staff members opinion does not reflect accurately on a company in my opinion .. We (my other half and I) have employed many folk over the years and I’m sure I could quickly find 2 individuals with differing views on how we run our company ..

Whilst listening to feedback is very important .. you can’t keep everyone happy all of the time !

It’s interesting how scancell add to the ‘posters’ section of their webpages .. very quietly !

Take care all ...

As the actual electroporation part of the administration has a duration of a matter of seconds and lasting side effects (if any) usually resolved within a few days … I think the janssen trial would have seen trial stopping incidents by now if there were any issues soley due to the electroporation part of their study.

""Actual Study Start Date ? : April 18, 2018 ""

Take care all (only my opinion as ever)..

Well, whatever the issue is, I'd rather it be sorted now than come across it after a trial had commenced …

Take care all ..

We know now that if there were major issues with the trigrid V2 device then Janssen would have come across them by now … They have expanded their recruitment to 13 sites now in Germany, Belgium and the UK … All gold standard authorities.. No reports of anything untoward?

https://clinicaltrials.gov/ct2/show/NCT03463369

Take care all..

New proactive? Says posted less than an hour ago?

https://www.proactiveinvestors.co.uk/companies/news/214474/scancell-in-vanguard-of-immuno-oncology-advances-with-two-technologies-that-show-early-promise-214474.html

Take care all..

That’s a good informative video.. thanks,

It seems the industries understanding of the mechanisms involved in tackling cancer is certainly deepening .. but still it’s going to be finding the right targets and combinations of targets that will bring it all to fruition and using these mechanisms to benefit individual patients.

Aside from scib1 and 2 .. scancell still at the ‘landgrab’ stage?

Take care ..

Very similar approach ? Could you explain how? Scancell is not a TCR or car-t company and have never manipulated directly any t-cells themselves? This is a long way from what scancell are doing ... Which is Identifying and patenting targets to be used in their own platforms and others' technologies...

Interested to hear your explanation of the 'very similar' approach?

Take care, and thanks.

Seems a lot was learned from the Prostvac trials ..

Take care ..

Re the discussion about T cell avidity and numbers of specific T cells..

The following write up is superb ! And mostly in plain English too ! There are some sections related to the above..

https://journals.sagepub.com/doi/full/10.1177/2515135518768769

Take care ..

That’ll be ‘ultra high avidity’ ! Lol..

Take care ..

I just received an e-mail ...

NXC (despite my reservations) is Mr. Evans!

Thought I'd share that as I was one of the doubters.

Take care all...

I’ve e mailed the golf company .. some nice pieces of art ... if you like golf that is ..

Take care ..

Having met mr Evans at a couple of AGM’s I find it very hard to believe he’s posting on any B.B.

He’s pretty much retired now by the looks of it so I guess he would have some time on his hands??

https://suite.endole.co.uk/insight/people/8294697-mr-david-eric-evans?page=companies

Take care all ..

One of Scancells patients was featured on BBC south in a story about the new Center for immunotherapy in Southampton ..

I just looked mr Worthen up and it looks like he’s still going strong .. (sorry Tom, hope you don’t mind) .. a great summary of his admirable career but it misses out .. ‘survived late stage melanoma’ !!

https://www.pallantchambers.co.uk/our-people/barristers/thomas-worthen/

Take care all ...

Lol... Great memories of the Tuxedo Princess !! Revolving dance floor !! What's that all about .. Tricky getting on and off after a skin full of 80 Bob !! Lol ..

Take care .. (Sorry for the off topic all) !

Morning ! Got to love the Northeast eh .. being from Hartlepool and pretty sure my geography is ok, but I make 15 miles northeast of Newcastle in the North Sea !?

Spent many a great night out in the Bigg Market and down on the Quayside (The cooperage and Red House) !

Student days eh ! Great fun !! Never lost a coat cos never took one out lol !!

Take care ..

I guess inanacos point was .. if there was better treatments for cancer, less people would be dying from it !?

Just a valid thought perhaps ??

Take care all..

It’s an expanding picture indeed .. a spiders web of opportunity.. valued by traders who are driven by a quick return I guess .. no prospect of a quick return , no value on aim ?

With most shares ‘held’ scancell is valued on the ‘liquid’ shares ...

I think we might see more interest on the OKing of the trigrid 2 device or deal with BioNtech but meanwhile the share price will drift and indeed some may look at this as ‘opportunity’ whilst others ‘doom’..

I wouldn’t mind getting to a million shares and of course, a low price with such a perspective is not a bad thing!

Only the future holds the answers !

Keep watching all .. whatever your opinion!

Take care...

I can’t imagine Merck not being interested in a platform technology that increases pd-l1 expression on tumour cells .. or for that matter anybody else !!

Take care ..

I know a few of you are keeping your eye on the success of keytruda ..

Here’s an interesting short article .. note the comment towards the end re Pd-L1 patients ..

https://www.biopharmadive.com/news/does-merck-need-more-than-keytruda/547419/

Take care all ..