RE: Just posted on LinkedIn "What makes our Moditope® immunotherapies unique? "10 Jul 2025 21:17
This v. positive info , the Initial Data pasted below from RNS just over a few weeks ago !! (Cohort 4, 26th June 25) , although very positive, it is old data, the initial data.
However, the fact they have purposely used this positive data again, a few weeks ago is interesting, especially in the light of what info, the BODs had access to when they wrote and published this RNS.
Have the BODs had access to new data since the older initial data? if so they were happy to continue using the excellent older data, as if it had not materially change OR were they blind to any further new data and so repeated the initial data - as its would be the only data they have available.
I know we are expecting a release of new data, anytime soonish, and that will be the official update -so i understand that there is a time an place to update the public on new data - but its all about what they were aware of in June, when they wrote the RNS . They surely would not repeat the data, knowing full well there has been a negative aberration, would they?
"SCOPE (NCT04079166) is a Phase 2, multi-centre open-label study, investigating SCIB1/iSCIB1+, with checkpoint inhibitors (CPIs) in late-stage melanoma and will enroll 140+ patients across four cohorts. Initial data from 25 patients in Cohort 1, receiving first-generation SCIB1 ImmunoBody® in combination with checkpoint inhibitors, ipilimumab and nivolumab, showed 84% disease control rate, 80% progression free survival (PFS), with a 20% complete response (CR) rate, and 72% ORR, demonstrating a significant improvement over standard of care treatment."
Sorry to bang on about this but how much is reasonable for the BODS of a company to know about the progression of the trials ( assuming the trial is not a blind trial, so info is much more available such as this trial) GL all Vas