Member Info for scardey_cat

Used an old abacus I bought when we first started developing our LFT...Jeez, has it been that long!

Wyndrum, that appealed to my mathematical bent.
31 Dec is looking fairly certain for an RNS, if nothing sooner.

Increasing % Chance of RNS
Date Days % Chance
Left RNS
23-Nov 27 3.70
24-Nov 26 3.85
25-Nov 25 4.00
26-Nov 24 4.17
27-Nov 23 4.35
30-Nov 22 4.55
01-Dec 21 4.76
02-Dec 20 5.00
03-Dec 19 5.26
04-Dec 18 5.56
07-Dec 17 5.88
08-Dec 16 6.25
09-Dec 15 6.67
10-Dec 14 7.14
11-Dec 13 7.69
14-Dec 12 8.33
15-Dec 11 9.09
16-Dec 10 10.00
17-Dec 9 11.11
18-Dec 8 12.50
21-Dec 7 14.29
22-Dec 6 16.67
23-Dec 5 20.00
24-Dec 4 25.00
29-Dec 3 33.33
30-Dec 2 50.00
31-Dec 1 100.00

This paragraph in the document stood out for me. It confirms the close relationship of the ABC-19 antibody test to the AZN/Oxford vaccine. Quite probably the Oxford vaccine will become the vaccine of choice here in the UK, so you have to think there will be a huge demand for the ABC-19 test and that the potential 15million tests in the government framework, will be fully called off, followed by further purchases thereafter.

"Through Oxford University’s involvement in UK-RTC, the research teams at Abingdon Health that developed the AbC-19 Rapid Test have had access to the same antigens used for developing the vaccine candidate ChAdOx1. The assay is therefore designed to look for precisely the antibodies which the vaccine encourages the body to produce. When tested for sensitivity and specificity with human blood samples, the AbC-19 Rapid TestTM performed strongly, closely rivalling well-established ELISA and CLIA based alternatives, as we outline in figure 4."

Sure feels good not to have the 'Sword of Damocles', that is vaccine news, hanging over our heads now. Gives us a nice clear run to Christmas with less fear of another catastrophe.

Yes, you can open on IG spreadbet. Increased mine this morning.

Was six figures up on this beauty not so long ago. Nice to see some of it coming back. Whatever the outcome, have to say it's been one hell of a journey/experience and will fondly remember top class posts from the likes of amatuer.invest from yesterday. Superb sense of humour!

[Doh85,funny you mention it. I was up at Sir Als new house at the weekend, 5am crawling through his bins.
Found a pile of old tea bags, tins of Yorkshire bitter.
Then, under a copy of "Country House" I found them.... swabs. lots of them.
I took them home to analyse. I felt I was into something.
Came to conclusion Sir Al had spent most of the weekend clearing wax from his ears.]

Yes, I suppose Christmas postal delays wouldn't really cut it Wyndrum :-)

May have delayed the RNS by a day out of sheer embarrassment about yesterday's (perhaps) leak inspired rise. Would look less embarrassing with that rise out of the way.

When you think about it, if the Oxford/AZN vaccine turns out to be in the 80's percentage wise, that's even better for ODX, since there will be even more demand for the ABC-19 test to see if it's worked in individuals. If it was a nailed on 99% then less need I think.

SensibleGuy: Really interesting interview that. Listened to about 15 minutes of it, but might watch the whole thing tomorrow. Thanks for sharing.

Affimers are reagents that can be used to attach to the virus spike proteins, which is how they capture the virus on the LFT, for instance.

mRNA technology is something quite different. These mRNA vaccines introduce some of the virus RNA into our cells (rather than traditional vaccines that inject us with weakened or dead whole forms of the virus). The function of RNA is to make proteins. So, the virus RNA that's introduced to our cells, starts making proteins that are specific to the virus (and needed to replicate itself) - let's call it Protein X. Our immune system learns to recognize Protein X as being alien and musters it's defenses to eliminate it. So, when the vaccinated person is infected by the actual virus itself and that virus starts making Protein X in order to replicate itself, the body quickly starts destroying this protein, subsequently preventing the virus from self replicating.

So, in short, I can't see any use for affimers in these mRNA vaccines as there's no requirement attaching these reagents to anything in the above scenario.

Think you're reading the wrong article junior. This article is actually in our favour.

An interesting article by sharebuyers which shows that BMJ has a chip on their shoulder. Not to mention dismal deeks was named too.

https://www.sharebuyers.co.uk/shares/the-bmj-continues-to-be-used-to-bash-the-uk-rtc-and-its-all-starting-to-look-very-questionable-heres-why/

bump, bump...

Bump...

...except I think the penalty is an all expenses paid vacation in Siberia

They've been doing the same thing in Russia for some time now.

I'm a massive Avacta fan...I liken it to being my Manchester City of the share world.

I just wonder sometimes if we've missed a trick due to AS being a scientist with an EGO, who inherently strives for perfection. Would we have been better placed having a hard nosed, pragmatic businessman at the helm? Would that hard nosed businessman have said a few months ago, b@llocks to perfection, let's get something out there! Had we had a similar offering to Innova rolled out at the end of summer, what would the share price be today?

I still think perfectionism has it's place and it bodes well for our eventual LFT and BAMS tests, which I still believe will do extremely well. It bodes especially well for our therapeutics arm, which has mind blowing potential.

'Dit que le mieux est l'ennemi du bien' as Voltaire once said.

That's surprising. Mr Mandela seemed like such a nice chap :)

Easy to forget here that we're all invested in a company that has the very real potential of making existing chemo treatments about 1000% (one thousand) more effective. Trials to begin approx January. Chemo is a very effective treatment for cancer, it's just that whilst attacking the tumors it causes a lot of other collateral damage to our organs, up to the point where our bodies eventually just give in. Avacta's Precision technology has been shown in animal studies to have the ability to focus 90% of the chemo directly at the tumor, thereby massively reducing this collateral damage. Also, it's not like we're inventing a new drug, these chemo drugs are already well established, we've just come up with a very clever guidance/targeting system. I would think there is much more chance of a guidance system mirroring in humans what has been seen in animals, as opposed to hoping a brand new drug will do the same in both. How much is a share worth in a company with such a transformative/disruptive technology on their books. I would suggest, a lot more than today's price.

And then there's the diagnostics. What a Brucie Bonus that is!

There’s two ways of interpreting the deafening silence. One is that we’ve all been completely mugged and the other is that there’s some massive news on the way. I just can’t believe it’s the former. It would be like the crime of the century and a real head in hands moment. Everything the company has said to date leads me to believe it has to be the latter.