Member Info for RorkesDrift

Thanks. I'm looking forward to the magic £1.87

Don't ask why - insert big yellow fingers crossed

Step 2 - no more FOC tests for anyone other than NHS or FT education.

From Her4 study

tection of Her4 protein biomarker in undiluted serum. The Affimer-based sensor shows slightly
better sensitivity as compared to antibody-based assays available commercially (LifeSpan
BioSciences) but with a must larger dynamic range (1-70 pM for the ELISA kit), faster response
time, ease of use and lower cost. The Affimer sensor also showed excellent selectivity when
challenged with other serum protein. The prepared electrodes showed high sensitivity of
0.049 µF/ log CHer4 in undiluted serum with a detection limit lower than 1 pM. The biosensor shows
good selective measurement of Her4 in undiluted serum in concentration range of 1pM – 100 nM,
with very low non-specific response to serum proteins.
To date only a handful of reports in the literature have described the detection of Her4 in
serum so it is as yet unknown whether serum-resident Her4 represents a useful biomarker in cancer
or other diseases. However, the Affimer sensor, with its low background and broad linear response
range, will enable progress in this field. Furthermore, the fabrication method is simple and can be
applied for the detection of other biomarkers in serum samples, paving the way to new platforms for
alternative low cost and rapid multiplexed biosensors.

https://eprints.whiterose.ac.uk/127708/1/Zhurauski%20_Tomlinson%20-%20manuscript%20revised.pdf

According to AS no probably about it

The Vegetarian Society was formed in Britain in 1847. In 1944, a faction split from the group to form The Vegan Society.[123]

A 2018 study by comparethemarket.com found that approximately 7% of British people were vegan, while 14% were vegetarian.[124] The results of this study however are questioned by the UK Vegan Society who found that the sample was based on only 2,000 people.[125] According to The Vegan Society's larger survey, the number of vegans quadrupled from 2014 to 2018; in 2018 there were approximately 600,000 vegans in the UK, equivalent to 1.16% of the British population as a whole. As well as this, 31% are eating less meat – either for health or ethical reasons, and 19% are eating fewer dairy products.

Participation in Veganuary has become increasingly popular, with the number of people signing up rising each year.

A 2018 Gallup poll estimated that 5% of U.S. adults consider themselves to be vegetarians.[133][134] Older Americans were less likely to be vegetarian with just 2% of adults aged 55 and older saying they follow a vegetarian diet.[133] Younger generations of Americans are more likely to be vegetarian with 7% of 35- to 54-year-olds and 8% of 18- to 34-year-olds following a vegetarian diet.

Cannot find figures for Spain. I cannot say any more.

No presumably about it. 3+3 study works as you suggest except cohort 1 comprises 3 patients not 1. Given AS said that only one patient had entered the study at last update then they won't have moved onto cohort 2.

In most multi centre studies, different units start at different times. Drawing conclusions about trial outcomes based on a normal recruitment process is not required. Especially given only one patient at 90% normal dose. Trial progresses has planned - if you believe no news is good news be happy. If not, then feel free to make stuff up.

I'm actually blushing.

Biosensors offer Avacta an opportunity to get ahead of Mabs. Smallervsize, consistency, simplicity. Just need to sort accuracy and then you have point of care that gives a value output rather than yes or no. Huge potential being led by the Leeds group and a little under the radar.

That's the nicest thing you have ever said to me.

You touched me, right there

You can see HL to show either live or trailing price - default is trailing

if you are part of the community that does not eat and / or use animal products be aware that all LFDs except Avacta (and possibly Aptamer group) use antibodies created by animal methods.

If the vegetarian public were aware of this they have the option of an animal friendly test brought to you via the power of phage (alright, radio W.E. F.U.N.K) - testing centres secure your supplies.

Campaign via PR fairly simple.

Oh hang on........

His Lordship missed his morning tablet.

Has predicted by the newspaper a couple of days ago (and before that a month ago) the use of LFD instead of PCR is timetabled for before half term. So the LFD market expands. However, it still requires professional use, not HUA - you still turn up to a test centre. All of this has been in public domain for longer than this week - no need to invent imaginary sources or stories about over hearing in McDs. Tuppence get out now whilst you can.

These centres will buy in bulk and look to buy tests on the basis that they are good enough, not the best. Note the scandal of lfd +ve vs pcr -ve - lots of tests hit the mark. No need to buy the best. Therefore price (and Avacta margin) is key but given the squeeze on supply (again in news but also respiratory illness is going up and a differential diagnosis is required) there is room for a good profit. Avacta have been working on TT with Abingdon for what feels like years so current production is 1-3M based on Avacta info. Not the billions promised but as I said last week the cash will underpin the Tx (next time do the decent thing and acknowledge). Rerate is required - major one next Q2 when p1 trials reported but a new level above Jupiter short isn't far away. Expect the pump and dump invented news to come and go whilst they try to trade on the inevitable volatility in SP

Reliably informed by three different newspapers. Well done

Thanks for posting - I might have on another Old Peculiar to celebrate.

Avacta have CEMark - suspect they have hit the various requirements given submitted for HUA. Plus I have reliably been informed there is a shortage of LFDs and that is before PCR switches - that volume is now in play.

Have or love the govt make an announcement and then work out the detail of the list on the actual day it goes live. Jeez. Makes for an exciting next 9 days.

I did say 10 days yesterday - based on stuff in newspaper admittedly

I liked the "power of phage"

Sounds like a late 1970s funk band - get on up, gotta wear sun glasses that's the law, take it to the mother ship....

Its because the have no kneed.

Still showing short.

Do they blink?

Taking mid point as 2M per month and therefore aimed at higher margin, non govt contract the profit would enable Avacta to cover their costs £500k per month (last annual report) and to contribute to the increasing R&D costs. At these volumes Avacta should be able to complete AVA006 and bring at least the next precision (Velcade) to phase 1/2. I aksi believe they can complete preclinical on AVA004 and another affimer bispecific.

Sales above this will widen the program, create an ability to go it alone on p3 first Ava004 and create a health cash buffer against another raise. That said I still believe they will go nasdaq and equity raise but after ava004 read out.

Again - LFD is just the fuel for the To but one that is protecting share holders from dilution at low value.

Relax, enjoy the ride

Slide says 1-2M from Abingdon?

Thanks Timster - I make it 2-3 million per month.