Member Info for Radium1

HelloSanDiego. re your...It's basically a summary of the results in advance of the detailed, peer review paper.

Not in my view.

gunto2020 re your...Simply not true. Early 2022. Huge difference.

Not so. Yesterdays presentation highlighted that 'top of the line' results could be available early in 2022. That means first in first out results. Those alone will not be enough to be statictically significant and certainly nowhere near enough to seek approvals from the various regulators. Full P3 results will probably take as long as the P3 requitment period and in my view unlikely to be available before mid 2022. Approvals even longer, assumming positive results, and that is a gamble in itself.

And, what if Active2 turns out to be inconclusive, or worse...a dud?

gunto2020 re your...Simply not true. Early 2022. Huge difference.

Not so. Yesterdays presentation highlighted that 'top of the line' results could be available early in 2022. That means first in first out results. Those alone will not be enough to be statictically significant and certainly nowhere near enough to seek approvals from the various regulators. Full P3 results will probably take as long as the P3 requitment period and in my view unlikely to be available before mid 2022. Approvals even longer, assumming positive results, and that is a gamble in itself.

Extracts and bullet points…

Mercks’ Laboratory studies have shown that molnupiravir is effective against all strains of the coronavirus, including the dominant Delta variant.

Merck is currently conducting two Phase III trials of the antiviral it is developing with Ridgeback Biotherapeutics — one to treat Covid-19 and another to prevent it….and the drug should be equally effective as the virus continues to evolve.

Merck said earlier this year that a small, mid-stage trial found that after five days of molnupiravir treatment, none of the patients taking various doses of the drug tested positive for the virus.

Carl Dieffenbach, director of the Division of AIDS at the National Institute of Allergy and Infectious Diseases, said that at least three “promising” antivirals for Covid-19 were currently being tested, and the results of these are expected in the winter.

In the light of the above and with Synairgen still in the process of recruiting for P3 trials, and meaningful results not expected much before mid 2022, together with the unpredictability of those outcomes, the above leaves Synairgen way behind the curve and not without substantial risks to boot. With the above major players well advanced in their antiviral research and about to bring a variety of high efficacy, general purpose antiviral treatments to the market soon, where is the investment case for Synairgen?

By mid next year it will be way too late for Synairgen. Events elsewhere will overtake them, see below....

https://www.msn.com/en-gb/health/medical/covid-pill-works-against-all-variants-including-delta-manufacturer-says/ar-AAP09RY?ocid=msedgdhp&pc=U531

MassiveRay, re your....It would be irresponsible of him to say 'definitely' so hopefully cuts the mustard im afraid...

Like I said earlier, 'hope' is not a sound basis for an investment. It's no better than the word 'luck'.... both of which are entirely evident here.

Kevinl1977, re your ....Risky to sell and miss potential jump if A2-3 success?

It was made clear in the presentation that the A2-2 outcome, in itself, will not be enough.

re your...It either has a therapeutic effect or it doesn’t - and the odds are it does.

Sorry to dissapoint. The fact is, untill proven otherwise, equally, the odds are that it doesn't. That being the case, the outcome here is entirely binary. Meanwhile, an investment here is not alot better than the potential outcome from the the flip of a coin....and a long nervy wait.

MassiveRay, re your...'Hopefully' is the appropriate word!

'Hope' alone, has never been a strong investment argument, even less so when it is coupled with long timelines and the use of the word 'luck'.

Shpunken....nevertheless, the outcome is far from certain. That is why investors and Synairgen need a lot of luck and hence their pervacious use of the word...hopefully.

Even if some initial top line data is available early next year and that remains a big ’if’, it will come out on a first in first out basis, and that won’t be enough for EUA, BLA and MAA approval applications. Reality is, mid next year for that and a lot of luck is required between now and then. For me, there was too much use of the word ‘hopefully’ in today’s presentation and so, with this uncertainty and the extended timelines, I’m out.

Since I couldn't have said this any better, I decided to bring the following over from the advfm bb, courtesy of gowlane....

Well you meet all kinds on an investor forum but the new poster on the LSE board who claimed that growth was weak from Q1 to Q2 had me puzzled, so I looked it up again. Revenue up by 15% in only three months, profit before tax up 43% and net profit up by 87% and someone pops up out of nowhere who thinks that growth was weak! Lol! You cannot read anything into short term fluctuations in the share price Since we joined the Nasdaq, daily swings of 5% seem to be quite common, but they mean nothing. It is hard enough to find a really good share, might as well stay on board when you do. This one must be good for another 100%, in my opinion anyway. But it might need to get a good set or results for 2021 under its belt, the trading statement in early January should answer any lingering doubts in the market. As Jesse Livermore wrote a century ago it was by sitting still and doing nothing that he made most of his money.

It's the first day of the quite period. No further news now until results day. They sure know when to apply the full downward preasure. Hold tight or take advantage.

Incidentally I see nothing of the ‘doubt’ suggested by our resident No.4
I very much embrace YeildFanatic's view on a possible acquisition by Tremor…We can keep speculating here, he says, as to which acquisition targets would make sense but the fact is that there are MANY potential targets out there, but not many with the adequate scale. $300m cash + the ability to issue a decent chunk of stock -> bringing the ability to bet big…..We could even see a potential $1B deal here - which would be dilutionary to existing shareholders, but which could represent the next step of the transformation of $TRMR into a potential behemoth….I guess what I am saying here is, don't be surprised if you see a big dilutionary issue. Personally, I WOULD WELCOME IT...so long as the deal is transformative. And I believe $TRMR management team have shown their ability to source good transformative deals and execute well.

I also, would welcome such a transformative acquisition, indeed I’m hoping for it and expecting just that.

Qwertyii…latest…(i)Some doubt starting to creep into yield fantastic latest post?
(ii) I see John09 and dagsteeth have now capitulated and sold out their holdings. Terrible. No doubt more will follow.
(iii) Anyway I will be OK if we can hold but the wider market is not looking good….

Qwertyii…18 Jun 2021 21:53…Well that was anticlimactic, so they sell a huge volume of shares at a 20% discount which ends dropping the share price and probably won't even sell the excess shares now while paying huge fees to stifle. Joke
Anyone could have told them that this was going to happen when you see how far as tech companies have fallen in the US.

Qwertyii…23 Jun 2021 21:08…Who would you want to buy anything in this market, unless they need the cash. Awful move to list on Nasdaq.Qwertyii.

24 Jun 2021 17:11…I glanced at advfn and there is a mention of a closed period holding the share back. Can someone explain this as I think its just another excuse to add to this failed IPO.

Qwertyii…07 Jul 2021 21:11…I was going to sell here at 800 and should have known that these stocks never keep going up forever. I see another SSP is going to list now ticker - tead- ….it does make me think that this has been a rushed IPO. I suppose when you look at the us peers these type of stocks are crazy volatile anyway so who knows where this goes. Highrisk.

Qwertyii…14 Jul 2021 13:17…Some in here were saying we had turned a corner. The downward spiral continues?

Qwertyii…15 Jul 2021 22:45…Well if q2 results are sh*t then who knows where this stock goes.

Qwertyii…16 Jul 2021 20:35…Busted IPO. I Think this will drop below £5next week. The discount IPO price was the tell.

Qwertyii…19 Jul 2021 11:05… I just saw the possibly of the price dropping and I wanted to see what other people's views were.

Qwertyii…22 Jul 2021 11:43…I don't think we're going to get a Tu next week, probably nothing until results in august. Low volume and just seems to be moving round with the wider market…

Following all of the above downbeat grist from Qwertyii then expects this board to believe that he bought another circa £80,000 worth of Tremor shares in the span of one month? See dated posts below…

Qwertyii…21 Jun 2021 14:56…I own 3,300 shares, I see it's about to go green on the Nasdaq.

(My calculation at £6.56 on the above date = worth circa £21,650).

Four weeks later, Qwertyii…22 Jul 2021 12:26…I have over 100k here now….

This guy blows hot and cold. He is the arch typical Phoebuss No. 4….The concerned holder who sways from being positive about the share to win trust before then losing faith and encouraging others to do the same. He works in tandem with our resident Phoebuss No. 1… Canute.

Qweritii…re your, ‘I see John09 and dagsteeth have now capitulated and sold out their holdings. Terrible….

Dagsteeth made it clear as to why he sold, didn’t he? He was diagnosed with terminal cancer in April and died earlier this week. Dags was a big player and just about everyone who followed hm on advfm was delighted to learn that he made a £1 million profit on his Tremor investment, before having to sell up.
How low are you prepared to stoop?

As for john09…. He took a £250,000 in profit with him, did he not?

I think all readers on this board have you very well sized up by now. You and canute... spawned from the same dung heap.

SNN. Re... It will take Q3 and Q4 results to get properly noticed and the SP to react to accordingly.

The above is absolutely the 'take home' statement within your post. Anyone unable to see ahead of Q3 and Q4 results, right now, will find their investment case in Tremor a retrospective one. Anyone waiting to invest in Tremor should get in ahead of the obvious, while they still can.

brubru24, re your C and P....''people will post any lie hoping to fool the gullible"

What a utter charlatan. Canute has been posting lies on the Tremor bulletin boards with the sole intention of fooling the gullible for a decade now. All long-termers here know it and can vouch for the accuracy of my posts in regard to his past history.
Once again. The guy is a basket case. Ignore him.

Millenium, I've brought this over here from today's Tremor lse and ADVFM Bulletin Boards....

brubru24, re your copy and paste of our resident Canute remarks....''I think it's best to trade and not get caught out again".

At long last, an admission therein that he was 'caught out'.

Yes, he lost his shirt in Blinkx (now Tremor) 5 years ago when he sold his shares at 50p, that’s around £5 in today’s money, if you leave out the 10:1 merger dilution etc for now. Those were shares that he had previously purchased at prices all the way up to £2.20 (£22.2 today). In those days, he posted about his purchases in Blinkx on the ADVFM board and I posted a dated and timed record of those events here. Back then he was posting that Blinkx shares were going to £3, (c. £30 in today’s money). The truth is, 5 years ago, while claiming to be clever, Mr Canute consolidated heavy losses on his Blinkx (Tremor) investment, from which he has never recovered. To add pain to his injury, Canute reinvested those lossy proceeds into Totally Plc. Totally’s share price was around 60/70p at that time. However, he had earlier bought into Totally Plc at higher prices than this, around 90p+.
Canute said about his investment in Totally Plc. On the 2 Mar '14 - 16:40 - 2231 of 3524. I've put my money where my mouth is. I've a huge amount invested and all in my ISA.
Seven years later and Totally’s share price is just 36.6p. Is it any wonder he worries about getting caught again. He has been up to his hucksters in losses for nearly a decade past.

This guy has zero history of successful investing. He is an absolute basket case. Ignore him.