Member Info for Prion25

Spin
https://www.southampton.ac.uk/news/2021/01/ace-covid-protein.page
short ACE form discovery does not predispose cytokine storm during interferon beta response
ATB

Thanks Matterhorn
Yes it does confirm Casanova et Bastard previous work and apparently its quite easy to test for autoantibodies in the lab. Also there may be a link to autoantibodies and long Covid which I hope Sng are investigating in trials
ATB

Thanks Brysoa
We have previously debated Extavia on this BB.I take your point about EU/French gov breaching the patent /licensing rules to save to save lives .They are the rule makers and not necessarily rule takers .

Scinv
Techically No , but in the circumstances of US with deaths far greater than 3 major wars you think the FDA would be eager to get a signal that the treatment works to save lives ?

Doc
Thanks for your opinion which I respect and value .Between everything it may be I have been more interested in the evidence for the science and not all the twists and turns in regulatory processes and various trials etc If what you say is correct it will test my patience little more ,but I am always optimistic that something good and unexpected might materialize sooner .Here's Hoping
ATB

I agree with Harchris and from my recollections a read out will be based on some threshold number, say 200 of the 610 across all global sites It is a matter of expedience that data is released so decisions can be made for approval .I stand to be corrected if anybody disagrees . Waiting another month or more seems to the antithesis of what was intended to obtain quickly a data set to trigger emergency approval

Thanks Joey
Good work
It seems the Chinese are so far ahead in many ways in Coronavirus related research .It almost makes me think it was made in China !?

Qd22
Your rant not to dissimilar to my rant a couple of days ago and is perfectly understandable The wait has been torturous and more agonizing when thinking of the lives that could have been saved Hoping that news will arrive before the Ides of March
ATB

Thanks Scinv for your analysis .Joey raises the evidence of autoantibodes in the role of severe Covid which in turn can be further investigated as possible cause of long Covid . Exciting times ahead

Scinv
Correct nothing to stop others using processes of neubulised interferon .But what is patented is Sng001 and the IP of hopefully the robust and exceptional findings throughout all the stages of covid19 Also its agnostic antiviral effects all respiratory such as COPD and hopefully the P3 will demonstrate benefits to long Covid and its neutralizing affects on all emerging coronavirus mutations .Not all our competitors will have this exceptional data

Apologies if already posted
The more contagious British variant "now accounts for about half of people infected with Covid-19 in France", Prime Minister Jean Castex said during a press conference on Thursday.

I think I remember a French lady scientist at the beginning of the pandemic working on neubulised Beta interferon 1b

Cannot believe the French PM would hail our treatment especially after the vaccine debacle and Brexit .

When AZ published uk trial results no data on the elderly because they were all compliant staying at home and not ending up in hospital Now the elderly in lock down and vaccinated before Xmas are not ending up in hospital How do they unbudlle the data between the effect of lockdowns and vaccine protection

Appears to be studies to demonstrate that Nipah and Ebola have an antagonistic effect on interferons and innate immunity just as coronavirus imo

Same article in Guardian accessible
https://www.theguardian.com/business/2021/feb/18/mps-fca-woodford-inquiry-investigation-collapse-investment-firm

Interesting article Shan
Especially highlighting interferon beta a a possible treatment for Ebola .I know Ebola is not a respiratory disease and Dr E Fish will advocate the I/V route but who knows what an agnostic nebulised anti viral can achieved against Ebola which is essentially just another interferon blocker .Sng0001 can Switch on them ISG genes .

Tremendous news .Hull was that a full recovery in less than 2 weeks ?

It good to know that somebody somewhere is getting a dose with a treatment that hopefully will save a lives and the news of this will propel us onwards

Matt Han C ...k "I hope that Covid-19 will become a treatable disease by the end of the year " BBC News tonight