Member Info for Prion25

Faye
It will take me all weekend to read it .Dr Mary has done his homework for sure and I believe He is currently undergoing P2 trials with IFN 1b .We had discussions on BB patents and whether he will be able to commercialise his drug or he may looking to get on the EU short list for faster approval. Just speculating

Fruits
Unbelievable and shameful Politicians focussing on local elections more so those who want to break up the Uk an d cause more chaos rather than keeping an eye on the ball with SA variants and fixing the damage of the pandemic

Fruits
Unbelievable and shameful Politicians focussing on local elections more so those who want to break up the Uk an d cause more chaos rather than keeping an eye on the ball with SA variants and fixing the damage of the pandemic

SYGGF up almost 8%

Mon ami Dr Mary tweeted on the Day of the HT results gave a "Une tendance favourable " a favourable trend a much better response than some posters on this BB on that day

Les données sng001 à domicile, en communiqué de presse.
Une tendance favorable.
En phase 3, plutôt cibler les patients dyspnéique pour améliorer le NNT

That article was printed 14/02/2021 lot has changed in India now they should approve it ASAP in imo

yes they doing Horizon screening the most promising and excluding i/v interferon But not our drug ? If they exclude our drug then they will have to exclude Dr Mary drug backed by the French Gov But then you back to EU anti UK politics Where is our antiviral task force should be doing this

They have good data on us and Dr Mary will it be the French Gov influencing?

Tatty
This is one of my recent previous just in case you missed ref Polar seem happy

Not sure about this item whether it was published before the morning before HT results or was it US time Nevertheless something to ponder over

Synairgen has shown early proof-of-concept data that suggest their medicine could provide a profound benefit to patients, potentially materially better than anything we have seen to date from some of the higher-profile companies,” said David Pinniger, lead manager of the Polar Capital Biotechnology Fund, who owns the stock.

https://uk.finance.yahoo.com/news/stocks-soared-covid-treatments-coming-040000358.html

Titania
Great post they ref work by Ratko in 2014 The recent HT and hospitalised provides stronger evidence of beta interferon works from RNS for those with severe breathing difficulties due to viral induced exacerbations due to coronavirus

"Analysis of the combined data from the Hospital and Home Cohorts showed that the more breathless patients are significantly more likely (>3 fold) to recover on inhaled interferon beta (SNG001) than placebo"

Perhaps they need to update the REF in the article once its peer reviewed perhaps I will email the MD who supported the article content I read something yesterday on the NIH its the world asthma awareness week

Trump should be credited spending huge sums Stockpiling millions of doses early in the pandemic with "no risk"approach not knowing whether the vaccine would work or not .Biden is naive just looking like the good guy The vaccines effort has been spectacular why would you change it . Would he have waivered patents early in the pandemic US public there was enough antivax fears microchip infestation adverse reactions etc and could you trust the rogue nations like Iran and North Korea not using the cover of the IP as a biological weapon

OAK
I have read the The Trial by Kafka if you referring to "Beckon he will come" I do't know where that came from but it felt biblical giving us hope for the return of PMJH . Kafka 's Trial was nightmarish hope RM has better luck Lol

Beckon and he will come

J CIT
Pleased you commented on the slides and agree some people may have missing the point t The confounding low signal problem in HT will be reflected for any other novel respiratory drug investigations including Boris’s wonder pill imo . Given our low signal for our therapeutic in the early intervention nevertheless with IFN beta the biomarkers show an antiviral response in sputum samples from COPD trials therefore this does NOT rule it out the use of the treatment as a prophylaxis in my view Severe breathlessness has been shown to prevent hospitalisations and pending Activ 2 to follow will support this and with P3 hospitalised data its all looking good to me

Jayne C
I have FWIW also emailed Concillium comms

Email the company Titania

Not sure about this item whether it was published before the morning before HT results or was it US time Nevertheless something to ponder over

Synairgen has shown early proof-of-concept data that suggest their medicine could provide a profound benefit to patients, potentially materially better than anything we have seen to date from some of the higher-profile companies,” said David Pinniger, lead manager of the Polar Capital Biotechnology Fund, who owns the stock.

https://uk.finance.yahoo.com/news/stocks-soared-covid-treatments-coming-040000358.html

J CIT
slide show if helps
https://www.synairgen.com/umbraco/Surface/Download/GetFile?cid=d885dcc6-2350-4dc9-b8f0-7415aa72f511

Fantastic research TT Investor's Chronicle would like to get their hands on that

Scinv
I only mentioned patents in the context they have the IP that demonstrates effect showing IFN beta on viral load in vitro in lung cells Then why are they not producing data in the trials in vivo in humans for proof of concept . Nothing to do with all the legal stuff