Member Info for Mumbo_Jumbo

it’s more wait and capital tied up..... damn

Let me see if I can request their presentation.

No. It was at Festival of Genomics late Jan.

Balanced - have you got a position here?

They recently presented results at a virtual meeting/conference. Unfortunately I was registered for it but I didn’t attend. I didn’t know the company till about a day or so after anyway.

Par for the course really... commercial discovery is rare. Though who invested knew the risks, there is no hiding place. You either win big or you lose almost all.

This well has been over 10 years in the making, shame it was non commercial.

Wigwammer,

Sorry to disappoint, not going to short or buy. Did come here with a view to buy, but not anymore.

Fundamentally disagree with the approach here.

Find novel enzymes from interesting species.

Wigwammer.... No. it’s not worth the effort when there are so many opportunities out there.

And also, Markets can stay irrational for longer than I can stay solvent.

Tesla is a great example.... it’s a short if there ever was one, but why would you fight the tide of sentiment that’s propelled it to unreal levels. The mad thing is that Tesla made money from selling their carbon credits to others to show themselves to be in profit.

Do the antigen tests have to be approved by MHRA before the contracts are signed?

Scrambler- why don’t you come back with something more intellectual. It will be more worthwhile in this discussion.

Ok fine, you are a bit ****ed off that I am raining on your parade. Your reaction shows me that you have very little understanding of what you invested in. I am not here to tell you what to do with your shares. Blind investing is totally your prerogative and I have done that myself in ARB. Complete punt on BTC rising.

I came to this share late last night, as it was recommended to me earlier in the day. Much to my surprise, 4d is an area that I have some familiarity with....

Two things then came to my mind.... where is the great novelty and making good bacteria immunogenic is a terrible idea. Nature didn’t design your immune system to react to your good bacteria. Even if it’s one species, how do you make it highly selective as the some of the good bacterial species are so similar, in any case they have a symbiotic relationship with each other.

Agree Nolupus,

TB is a great money maker, you just have to be on your toes and get the timing right.

Watching both BRH and IQAI.

Lets go with your shy reply......

What is a refined bacteria? And by that reply I assume you are Ok with getting the body to produce an immune response to a good species. Extending that further, its also Ok to have a constant inflammatory response, especially in patients who are already sick.

So what will happen to that 1 species, after that person has recovered? They just resolve to ensure that they never get that species in their gut, how will they ensure that it does not?

So everyone is wrong then, not keep it topped up as you go along. Have you thought of the possibility that not all the good flora is bacteria?

Let me ask you again, is it a good idea to get the body to produce an immune response to 'good bacteria'? Which is what they want to do here.

Sangijuelas1

Seres needn't have gone through such lengths. Good food and probiotics as i mentioned in other thread can have the same effect. Its about species proportions, antibiotics alters that balance by also killing the 'good bacteria' in your gut, whereas some of the pathogens like C. difficil have a way of keeping themselves in near death state, which when the antibioitic course is over, they can recover quicker than the good bacteria. So keep eating probiotics (fermented food and drinks) whilst you are on antibiotics, supplement the gut with 'good bacteria' and you are fine.

So you admit that at the heart of the 'biotherapetuic' that is being used with MSD is getting the body to produce an immune response to good bacteria, which as we know from Seres example, is that its a very bad idea to alter your good bacteria proportions. Even leaving aside the effects of being in constant state of inflammation.

We are what we eat. Good varied diet is ultimately the best.

If you have invested here, then by default its a yes, whether you have thought about this issue or not. Explain Why.

I will start with a No and explain my reasons briefly.

A vaccine, is vector with which you get your immune system to remove a 'harmful' agent from your body. This is a good thing, its what we want and how we have almost eradicated many diseases and saved countless lives since the middle of the 20th century.

Getting your body to produce an immune response to something that is very beneficial for us is not a good thing. Altering the 'good bacteria' proportions in the gut, and having a constant inflammatory response switched on all the time, it is the quickest way to alter the quality and span of life.

When you alter the proportions in your microbiome, pathogenic species seize the opportunity and run wild, C. difficile is one such example.

All these AIM fully funded claims are like a football manager in trouble getting the dreaded vote of confidence from the board :-)

Nolupus - hope they don’t do an evgen here.

Beginning to think TB is worth backing in BRH and iqai, though be prepared to jump out and not hold for too long.

Agree Kingalf. Hope the overhang clears quick.

Mcap doubles ..... not the way most were expecting :)

Money was going to have to be raised at some point. Was hoping for it to be at much higher level.