Member Info for JustHereForHemo

Prevail very likely will invest more, they won't fund all (I think) but as milestones are reached they can invest more, check out their website. But if when trials start vlad wants to raise more via placings? Fine, as I have said before I expect the sp to be significantly higher at that point. Really wouldn't worry about CAR-T. Its not like vlad is taking over a hospital wing and a staff of 50 to run a mass trial.... ONE patient at a time... one. Manufacturing the CAR-T in house....

10s or 100s of millions for CBR is what's needed. Serious cash, IMO that's what he is thinking about, but who knows, hopefully there will be a livestream or some sort of update.

What difference does IND make to the JPM Conference?

IND applies to CAR-T and he is perfectly free to say that Hemogenyx are preparing to start clinical trials, have brought onboard Prevail, a clinical hold was applied by the FDA and they have completed the necessary changes as agreed with the FDA. In terms of the JPM audience with regards to HEMO-CAR-T thats enough, there may be interest in an early stage partnership or licencing for HEMO-CAR-T, but its very unlikely thats what Vlad is going for. CAR-T is the known entity here, he is set up for trials and any offer he gets next week would be 20-30x better after results (According to Vlads interview).

Its going to be the same as the last few conferences, its about CBR. It is a platform that can treat Viruses, Cancer, think he even said some bacteria at one point. He needs investors to invest in CBR and he needs partner Pharma willing to take on development and testing of CBR for specific targets. Already we know they have tested on Measles, Ebola, Covid, Non-Hodgkin Lymphoma etc. Every one of those is going to need a team, its going to require in vivo and in vitro testing if not already done, its going to need pre-IND enabling studies, toxology, IND preparation etc.

I honestly dont think half the people reading this recognise even a fraction of the opportunity they are sitting on here. Just remember we only need ONE. One licencing deal for anything is going to be multiples of the Hemogenyx current mCap and we have CAR-T, CDX in talks and vlad off next week seeing investors for CBR.... Just one.....

Good to see a bit of blue, interesting that the MMs moved it up and immediately bought 135k at 2.31, this is higher than the buy price for last few days so only reason for that is a larger premium buy, expect a delayed buy to popup for around 10:30 paying something like 2.35. Anyway, onwards and upwards hard to be patient when we know how close we likely are to clinical status!

Mornington, the saving grace here is that triple is possible, Its true we have over 1bn shares now in issue compared with like 400m when it was 14p but the potential now and underlying value is many times greater. The dilution is not that bad when you look at many of the other small caps we all would be familiar with back a few years ago, the likes of Vast or Copl. Over the same time period if you look at the dilution there, vs cash raised and losses sustained by shareholders there is no comparison. The number of small caps that have to do 10,000% just for many shareholders to break even is scary, I give Vlad a hard time for some of his decisions but Hemogenyx HAVE survived an incredibly hard multi year winter. They are on the cusp of clinical status and whilst we have seen 300% dilution it has added value, made progress and had only limited damage to the potential.

My bad...

"This aint rocket science. End to end, taking a sample from a patient to having a CAR-T treatment ready for injection is" 10 days from memory and Vlad said before a FULL run including testing was about one calendar month. Ergo we are balls deep into that window. I know Vlad likes to take his time and be thorough but its one test to satisfy the FDA.....

How on earth could I confirm if the IND has been submitted or not? I can confirm I remain 100% confident in Hemogenyx and I can confirm that I believe they will be clinical in the very near future.

If the brokers knew much either way there would be alot more buying or selling, knowing the IND had not been submitted when they last spoke to Vlad is irrelevant, you cant trade unless you know WHEN.

WHY would IND not already being submitted be a kick in the**?

There is every chance the IND has not been submitted, does that mean it wont be submitted tomorrow? Or Monday? Nope. Where on earth does February come from?

"As agreed with the FDA, before the resubmission of the IND, the Company will perform an additional process qualification run of the end-to-end process for the manufacture of HEMO-CAR-T cells using the new LVV and we will now put this process into effect."

"We are pleased that we have a clear path to the lifting of the clinical hold. We are now working hard to complete the schedule of work set out in the plan presented and agreed to by the FDA and to re-submit the IND as expeditiously as possible to move forward with clinical trials of HEMO-CAR-T."

This aint rocket science. End to end, taking a sample from a patient to having a CAR-T treatment ready for injection is

Https://www.biospace.com/article/biopharma-closes-2023-with-flurry-of-m-and-a-activity-from-astrazeneca-bms-roche/

CAR-T is looking toasty hot

Kvetch... curmudgeon.....

If IND was sent they would not have waited until today for RNS.

Today is the return to work after the holiday when work is done, if the remaining work in submission wad only a few hours then I'm sure Vlad would have just done it before Christmas.

Looking for an excuse to moan and be negative as we just start 2024 is just sad. I'm expecting a very positive few weeks, chill out and try not being a wet blanket. Unless you just really enjoy being so negative.

Happy new year!

From what I am reading 2024 is the year of the Bull.

If predictions and overall sentiment is to believed its going to be hard to lose this year. Big and small the bears are looking to exit shorts and go long. Very recently there has been alot of M&A activity in the pharma small cap sector.

Lots of big pharma heading towards patent cliffs.

Inflation down and predictions of rate cuts for March.

2024 really could be fantastic and not just for Hemo but all the small caps which have survived the past few years so good luck to us all!

Of course... if hemo files IND and moves clinical in the coming days or weeks?.......

Socalist the more the merrier lol!

Blastoid I had a look at SAR, looks like overhang from their funding, it's nowhere near as bad as the CLN we had here but still an anchor. Looked at lead candidate and its targeting a 20bn psychosis market where one of the leading bio treatments was licensed for 100m up front an like 800m in milestone payments.

It's not Hemo, the pipeline is smaller targeting a smaller market with lower commercial price tags and more competion HOWEVER....

It like all small pharma has had a horrible year or two.

The potential for a licencing deal is huge once they are in phase 2.

The warrants are at a premium and not a concern.

Honestly, if 2024 is the year of the bull, if money returns and interest rate cut etc SAR should do well. At some point I will top slice hemo, when I do it would be a pleasure to join you there :-)

Goes without saying I agree 100% socialist, been ridiculed for years for saying £1.80 remains a very realistic target. But yet I keep saying it and I'm still here. I understand for many 10,000% gain even over a few years sounds impossible or like a fairytale. Maybe. But pharma is expensive, there are many big pharma heading towards a patent cliff, they are well funded and when Vlad has clinical proof this works they will have to pay the price.

IND is close, Hemo will be clinical, the current mCap is irrelevant, it's a price set by a bunch of traders, market makers and early investors. When hemo are clinical, when they cross the 50m threshold, when trials start we will see what the market thinks.

Get clinical results for CAR-T, sell it, use the funds to pay for years of CBR development never needing to go back to the market for placing until ready for CBR trials is the ideal scenario here.

600m for HEMO-CAR-T fine, great price, fair and plenty of examples higher and lower.

600m for HEMO-CAR-T and CDX and HuPHEC AND CBR THE CURE FOR ALL KNOWN VIRUSES???? NOT A FUDGING CHANCE! I would take my millions at 51p and fly to New York and shake vlad screaming "you fool! What have you done!" I would then fly on to Vegas and play poker for a week....

i am 100% transparent about why i am here and happy to stand by that conviction. i have accumulated millions of shares in hemogenyx and i believe moving clinical and beyond will cause the sp to re-rate making me alot of money. i am not happy its taken so long and i strongly disagree with many managerial decisions vlad has made over the years, but my belief in the science and potential upside has not changed. i dont see any contradiction there? but you in your posts clearly lack any belief that hemo will go clinical/rerate in the near future? i just dont get it. i have been in shares before where i believed in them, thought they would deliver, saw warning signs, took a loss and sold.

hemo is different, i have seen lots of errors in judgement, stupid mistakes like just **** poorly worded rns's, bad funding decisions, using the same brokers with same traders time and again for placings, failures to update website despite assurances, taking far to long to do fundamental steps such as ind due to complete refusal to delegate. p1$$ poor investor relations, failure to treat the company as a public company with fiduciary duties to shareholders when making decisions, failure to respond and react quicky to mint when they demonstrated bad faith, refusal to accept oversight in favour of grants etc. it would be foolish to think i am some blind sycophant who kisses vlads backside and thinks he is god, could not be further from the truth.

i have done the research, i know what car-t is worth, i know what licencing deals have been done in recent years and at what stages. i have seen what happens to pre-clinical oncology pharma when they go clinical. i have looked for comparable companies at this stage or phase 1 and know what hemo is worth inspite of what its currently valued at. i know the risk discounted value of cbr if it meets even a fraction of its potential. i have read the rns's from a year ago, seen the interviews and know that a single pq run of car-t will easily be finished by now. i know bad news would have been rns'ed by now so i fully expect a positive rns in the very near future.

i am here because i am invested in hemo, i have very good reasons to believe the sp is wrong and it will re-rate. this mcap is not sustainable. vlad has his faults, he has made mistakes, he is not perfect. but... he is a brilliant scientist, he has kept hemogenyx debt free, he has some powerful backers and he is determined to prove everyone who doubts him wrong. as for £1.80 being unrealistic? whats that 2bn? go tell the avct fans that it will never hit 2bn see what reaction you get, and they basically have something like cdx, at 350m 2bn much closer and more realistic for them. when hemo is 100, 200, 300m... suddenly 2bn wont be so unrealistic. will it take time? sure, but i am not going anywhere, 5 years and counting.

Stu is still around, but bought in and that account is for deramping.

Please Google difference between goal and commitment....

Still fail to understand how someone so negative and bitter would hang around for so long if they don't believe in the company.

It's not just me right? Other forum readers find this contradiction annoying and pathetic aswell right?

Whoopee doo.. tuan placed 2 crossing limit trades with 10k shares, then comes to post about it a few minutes later. Value of the trade 200quid the actual cost? If tuan is a PI then a few quid, otherwise zero.

I don't even bother reading or engaging with tuan posts any more. It's an automatic report every single time and encourage everyone to do the same. There are traders like pumpkin, fine. There are bitter annoying posters like HT, again fine, I don't ever report. But tuan? It's a multi account poster, actively attempting to manipulate the market often with blatant lies. But always with fud and disruption. Just report their posts and ignore, eventually they will dissappear and the stupid attacks will stop. Also despite the fake -7% because of the UT the sp didn't really move and it opens blue tomorrow so don't sweat it.

Of course this price is not realistic or sustainable, none of us would be here if we thought this was even remotely like a fair SP. We are all here to win big, taking Vlad ALOT longer than expected but doesn't change the facts. Unless you lack the fortitude to wait and let your emotions control you this SP will rerate soon enough. Not sure why your still here HT, if I didn't believe in Hemo I would have cut and run ages ago. Sticking around if you don't believe in the company is bonkers, anyway Happy new year in advance, I have the kids.

There is ALWAYS a retrace, on IND it will spike and fall back a little. If you have a time machine or believe you can call the top then you can absolutely take advantage. Otherwise its like catching a falling knife when sp is falling.

If you can live with the potential of the sp continuing to rise and getting locked out if the retrace never goes low enough to let you back in then trade away and good luck.

This is not a trade for me, for me the pain of missing out on potentially life changing rises is too great to risk for 10,20,40 even 100%.

Everyone must do what is right for themselves.

The market is heating up.

https://www.cnbc.com/2023/12/26/bristol-myers-to-buy-rayzebio-for-about-4point1-billion.html

As frustrated as we all are waiting, its not unlike a child waiting for Christmas, pretty confident of what Santa is going to bring but still hating the wait. I HATE the wait, but the RNS's are there that have been crystal clear, IND is near and the chances of success are extremely high. Its not just Vlad who thinks so the FDA have already reviewed the full IND and found one issue. Prevail are experts and THEY are happy to come on board. Frustration at waiting is fine, but writing is on the wall, its coming and soon. Tuan is here because they have a job to do, but they are an anonymous troll. They can say whatever they want, they can cr@p on your face and call it chocolate or pee on your head and call it rain, it does not make it true. RNS's are there, there can be ZERO new placings until Feb (Per Main Market rules). So trust the RNSs and common sense. We have waited this long and its about to be over. Every likely hood clinical status is going to slip into 2024 at this point but its bloody close, dont let a few weeks slippage detract from the fact its a huge transformational step. Anyway, have a very merry Christmas / Happy Holidays to those signing off today.

Same here, I am 99% convinced they have done the PQ run and whatever testing or preparatory work is required for the IND. It was always going to be tight but I expected them to squeeze it in before Xmas to clear the deck so to speak before going off for the holiday. So I am disappointed we have not had an update before today. This is my last day at work and kids are off school now so computer access during trading hours for next 2 weeks will be very limited and I assume that is the case for most. If good news does drop in the next week or so the audience will be greatly reduced so probably prefer Vlad to wait now until new year. BUT.... Its Vlad, timing an RNS has never been a strong skill for him so will continue to check daily for RNS if I can. As for Tuan..... Seriously? We still have anyone questioning this? That user is EITHER a full time trader/troll who has lots of accounts and prefers to make their money shorting OR they are part of a team with shared accounts. One person or many, dont really care, same "pool" of accounts as 121,131, BB, snooker, etc and more I am suspicious of. They have their rules about how the accounts should behave and post, new line after x words, signatures they should use, grasp of english etc. But all too often they slip. Given this board is owned by Jarvis who handle lots of the placings for these small caps its not a stretch to assume half of these trolls are paid and there is some connection. At some point will reach out to the FCA about Tuan, it worked for 121/131/bb etc which have been removed. I think these accounts forget that Market Manipulation is an actual crime, even if LSE board are more than happy to allow it.