David Talbot spoke at the London South East-Red Cloud Securities Global Mining Special. Watch the full video here.
Looks like Hemogenyx have begun using their clean room in the new lab, presumably they still have to have it certified so I am not sure we can call it finished or ready to go but fantastic to see actual progress none the less. Such a difference in facilities compared to earlier videos.
You keep posting irrelevant links omitting that they are nothing to do with Hemogenyx? This is for Chronic myeloid leukaemia, its not a cure and still has side effects, zero relevance on this board? Perhaps if it was targeting AML which CAR-T and CDX are the primary targets it would be remotely relevant.
The chart shows a trending upwards channel with sweet FA volume, on twitter I see the chartists are starting to promote Hemo also so fully expect people to buy just on that alone. I dont care what the charts say, I have bought and hold because the science is good, there is no toxic debt and they are funded into clinical trials. In this market not being diluted is everything. Dr A and Swazers are in a pretty influential trading group and if they are saying the charts look positive that will have an impact so for those who only care about the SP in all likely hood you will be rewarded soon enough.
Starts 6 minutes in.
Maybe take a chill pill and join the zoom next week and ask your own questions and lay off the annoying digs at Vlad and the company, is it really that hard to wait ONE week? Your last few digs have been completely unjustified /downright wrong, and this is for a company your invested in.
The tweet is public, you chose to read the wrong way into it which is impressive, its very clear Vlad was highlighting how he is different to many CEOs who just bleed the company dry.
My comment about the lab is in the last interview you just have to actually listen to it *(Face palm emoticon)......
There is a difference between being built and being certified. Vlad explained this already, the labs are not completed until they have been signed off by a 3rd party, its not JUST about the actual room/filtration/equipment etc. It includes the processes and handling procedures, the staff and the training and successful runs of clinical grade product. He was hiring multiple staff members this year, a manufacturing associate and an independent quality controller.
Vlad is not building a McDonalds which you can throw up pre-fab in 48 hours (YES, I have seen one put up in 48 hours!), IMO its the staff/training/documentation and arranging 3rd party certification which has been taking time, all outside the scope of Janus.
Worth highlighting that once this certification is complete the company stated that in future this could be a possible source of revenue producing cells for third parties who lack manufacturing facilities.
Or perhaps he wants to highlight that most public post-IPO small caps are lifestyle companies where the CEO floats to pay an inflated salary. Vlad however floated to raise capital to enable the salary and as far as I know his salary is nowhere near the 500k, IE he is pointing out that he is different, he is frugal and he wants to deliver the science on the money he has. Instead of having a dig maybe consider that this man is running the company your invested in and he is more inclined to care about shareholders like you if you dont treat him like ****?
HemoKnowledge is it fair to say there are no known other competitors actively working on a CAR-T treatment for FLT3+ R/R AML that you know off? So even if there are a number of other approved CAR-T treatments they are for completely different diseases and there for not competition merely validation of the approach?
Worth remembering as MrIndia points out, these are events that vlad has CHOSEN to do, he wants to involve shareholders and provide more information. He is doing it because he loves the science and is excited, some will join looking only for a snippet of information on which they can trade. A line to justify them dumping or buying. Its sad its like that,but I hope that Vlad bears that in mind and does not say too much in terms of exact timelines, I want him to neither give the impression of news imminent or long in the distance.
Big news should catch us all by surprise and give no advantage to traders who wish to trade/buy at the last minute and dump on update. That said, its fair to assume there will be updates soon, his interview did allude that the Master cell line work with selenix was almost finished and it was several months ago the un-named partner started working with Hemo to validate CBR in the level 3 facility.
Always the optimists post the most :-)
Quit focusing on the SP every 5 minutes and look at the bigger picture.
If people think Hemogenyx will have an mCap of 13mil today and that we will just motor along for the next 6 months and jump to a more realistic mCap on IND RNS then they are mistaken, nothing moves in a straight line. Remember your fellow posters are on here dedicating THEIR time just as much as you are following this stock.
Just like you THEY want to jump back in before the SP rises. Do people think that the SP will sit here for 6 months and everyone can jump back in the day before an RNS at or below the price they sold?
The traders who have sold will compete against each other, its a game of chicken for those who are out, not a game I care to play but feel free. Only the lucky few ever catch the bottom and in this market irrespective of what hemo are doing when the tide turns and the market knows the bear market is over we will recover like all the rest. This share will re-rate and along the way we will have other news, other updates and all those who want to troll are just gambling they dont miss the next rise. All games, good luck to those who want to play!
And yes MrIndia, have a good weekend :-)
Go watch Devils on sky :P Very good and shows you what some of the people behind the scenes are like. Credit goes to Lunus1 who recommended it to me :-) I am on season 2, but be warned its only available to download for another few weeks.
Yes PTB I get the frustration also hence not swearing at people, I get where people are coming from, even HT and MrIndia and the like, but so much of the posts are emotional reactions based on their perception. Very few people who post actually take a holistic view of Hemogenyx and try and look at the bigger picture. IF you erased CAR-T would hemogenyx suddenly be worth £0? No it would not, so what is a fair value for the company considering they do have cash in bank to get to clinical trials? Moral of the story is, there will be days like today that are over reactions, I unfortunately did not have cash set aside to take advantage, my mistake, I will add when I can but it wont be this week.
HT, I have said worse to him over the years, yet he was still friendly when we spoke on zoom, everyone is entitled to lose their head once in a while and then be man enough to get over it and move on. I am sure we have fallen out in the past? I cant really remember :P Anyway, like I said before CBR is much bigger for me, what will move the SP? I dont know, but then again none of us mere posters are going to know about significant news or deals until its RNS'ed at which point you missed the boat. Companies like this make people rich when they get in early and hold, not for a RNS on a given day, thats what oil stocks are for.
Anyway, IMO todays reaction WAYYYYY over the top, hopefully the discounted price lasts until my next top up though. Have a nice evening all :-)
PTB welcome, you picked a good day, lots of unhappy campers but great investment. The single issue today is lots of people clearly planned to sell on the IND application RNS and that is unlikely before December so those who were set on that single RNS have decided to sell now at a loss so they can get burnt elsewhere. CAR-T is a big part of Hemogenyx, its the lead candidate but its not the only one and in terms of target market potential its one of the smallest. Dec 2022-Jan 2023 for Ind is likely and yes it will be a major inflection point going from pre- to clinical but there will be other updates along the way that will make it clear 13mil is not a realistic mCap.
Micky, its never been said end of may for IND, it was the PIND meeting pushed back until end of may. The company never set a date for IND because it depended on the PIND and what the FDA required. Personally I didnt think it would take anywhere near as long to get a clean room signed off but apparently it does take a few months. So be it. Boring process has to be done, saves company millions in costs so yea....
HT, instead of wasting your time complaining here just join the next zoom and actually engage with the man, he wont bite.
Micky, I was not targeting you with that comment, I was just asking you about the meeting as I actually thought you were in it, if not no worries, please join the next one.
I respect your and everyone else's opinion but I am also entitled to my opinion and in my opinion this repeated pattern of people obsessing over one single RNS with which they have decided to trade on is toxic, it happened with CDX and now with IND date. To the exclusion of all else, like nothing else in the company has any value when IMO CBR is much more valuable than CAR-T by a country mile.
I get this mentality in mining or oil stocks where its all or nothing on a spud and its a binary play, but it would be nice if investors here spent a little bit of time actually looking at the multiple pipelines hemo has.
HT, please feel free to ask anyone who attended a zoom meeting if they expected IND before December, and yes there were many of us.
Micky, were you not on the zoom call with Vlad? I thought you joined? The timetable was crystal clear for IND application with the steps required so no there was nothing in todays interview out of the blue.
People need to grow up and stop sounding like children, pharma takes time, its been explained whats happening and why and along side that CDX and CBR are progressing nicely, so if people want to throw toys out of pram and have a hissy fit and sell, well work right away :-)
Barbershop if your available for hugs maybe you can nip over to see HT?
There is nothing new here(With regards to CAR-T), we knew it would likely be end of year for actual IND, he explained why in the last zoom meeting and it was very reasonable. But again this single obsession with nothing else existing except for this one single IND application RNS, its so toxic, its what happened with CDX those years ago, nothing else mattered, any updates that came out it was "...And what about CDX?"
Seriously, feel free to feel frustrated that CAR-T clinical trials are not happening this year if you wish but god sake, change the channel. If the only thing people care about is the CAR-T IND RNS then please sell and go away until December. Everyone else who has more than 2 brain cells and can see that CBR and CDX are moving along nicely and will update long before then, look forward to the Zoom call next week!
People really need to wake up to the fact that Hemogenyx is NOT a one trick pony!
He gave a fantastic interview where he made it clear that ALL 3 of the main pipelines are progressing and people focus on only CAR-T IND which says to me those posting are purely RNS chasers who are completely blinkered to everything but that one single RNS and will sell as soon as it lands? If it takes 6 months to file the IND because they decided to manufacture the CAR themselves in house then so be it, in the long run it saves them millions.
Lets completely ignore the fact they are in talks with other parties for CDX and a third party is evaluating CBR :P
The mCap is ~14mil and there will be no placing to knock it down before clinical trials start. Trials may be 2023 and if people ONLY care about CAR-T then sell, go away and come back in December. But I and many others will still be here because Hemogenyx is not going to just sit around for 6 months with no updates.
Might I suggest that actual investors, people who can open their minds wider than obsessing on one single RNS they are waiting on, join the zoom call and actually listen to and engage with Vlad and try and grasp the potential. Comments like below are just embarrassing:
"sounds like company were ill prepared" - No they submitted 70% of the completed IND and the delays are around manufacturing IN HOUSE CAR, something that was not initially planned 18 months ago.
vlad is a gambler - Are you serious? He is the most risk adverse and frugal CEO I have ever seen!
Pumpkin - Just a troll that adds nothing, I will see my valuation at some point.
jester16 - well the name says it all ;-)
Nothing is delayed, PIND happened as expected, IND was always AFTER they got the clean room signed off.
People are developing VERY selective hearing and taking what the want and so far its just trolls taking "no IND until December" which we assumed anyway but clearly a few just wanted an excuse to have a go.
Very good and positive interview, making it clear that he is laser focused on getting to CAR-T trials on the funds they already have and not incurring other costs that may derail that. IE unlike other shares that are being battered we are not going to be diluted to nothing (Cue Pumpkin with her broken record pointing out we were diluted last year.)
In terms of CAR-T, progress SOUNDS slow but they already submitted over 70% of the IND application as part of the PIND and the response was positive with some suggestions. Vlad makes it pretty clear that he intends to get it right first time and knows exactly what he has to do to keep the FDA happy so whilst I would love the IND to be filed tomorrow we all want it to sail though the review without a clinical hold from the FDA. Confirmation also that the first patients will be treated at Penn by Dr Gill is also great to hear as that . Basically CAR-T is moving well and pharma investors will be very happy with the level of detail provided in this interview, but it wont please traders who are solely focused on a CAR-T IND RNS.
CDX - Great to see the outlining of the master cell process, sounds like a key point in the CDX pipeline and from the sounds of it we should see an update on it soon. Also states speaking to multiple potential partners about progressing CDX into clinical trials. We only need one, but multiple is good
CBR - Previously was made to sound like Vlad had approached someone to test CBR on a live infectious virus in a level 3 facility. NOW it sounds like Vlad is allowing a company to produce and test CBR in their own facility "With their own hands" from scratch running in vivo and in vitro tests, so basically its someone who wants to licence CBR and are doing their due diligence first and not just someone testing on behalf of Hemo.
The number of partners Hemogenyx has continues to grow and this interview makes it clear that number will only grow. No clinical trials in 2022 unless something changes but likewise no fund raising, no dilution and multiple potential significant updates with regards to CDX and CBR. From an investor view point I appreciate the transparency and hope it continues. There is a risk of being so transparent with CAR-T as people will latch solely on that and say no updates for 6 months and ignore all else, but its the right thing to do. We are seeing a bigger more professional company developing that will demand a higher SP as it attracts investors who respect the progress made. We need to see this continue and with it, yes HemoTruth we need that website updated :P
I look forward to the Zoom meeting, the last one was extremely informative and I hope to see many of you there!
Thats 3% of the share issue.... And its not just giving away shares, its awarding share options or appreciation rights on a vesting schedule. MOST companies I have worked for do this for employees and the biggest beneficiary is the company:
It costs the company nothing, its like awarding a bonus or pay rise without handing over money
The shares or options vest in blocks over a period usually of 1-2 years so employees are much more likely to stay with the company improving staff retention
The company will get the strike price as revenue when the options are finally sold
The bottom line is though, the Employee Incentive Scheme is NOT a share giveaway, staff get OPTIONS to buy at the going market price which means the exact same price you or I could buy at today. Its the same as you or I buying a call option but its free and without risk.
As for asking questions, your free to ask whatever questions you want whenever you want to whomever you want, but with regards to the AGM they said questions with regards to the business at hand so dont get upset if your questions are not answered there. There will likely be more investor zoom calls in the near future, as HFH says, use one of those to ask your questions. Vlad does not bite and is polite, friendly and from what I have seen wants to answer any questions that he is allowed too.
Micky, its just proforma junk, you will be able to vote somewhere if you log into your broker and check like secure mail or corporate actions. Its always boring stuff like re-appoint Sir Marc or adopting the final results, it will guaranteed pass though, noting controversial this time.