Member Info for JustHereForHemo

MrsI you are 100% correct, and any patient that "leaks" probably would put the company in a difficult position, but its understandable we are all frustrated waiting.

What matters is the science as you say and whilst We the public dont get to see the test results, BP *(Who Vlad has confirmed in interivew) DOES get to see those results under NDA.

So for those reasons Vlad has my total and utter support, he has done right by shareholders and I back his decisions, but yes I too would appreciate more PR.

Alde, Slow your roll. I am not now or ever going to agree with you out of principal.

I have never said the PR is good enough here, I have always called for more DIRECTLY to the company, I just dont spend half my time attacking Hemo or making wild accusations about people dying or things going badly just because Vlad is notoriusly bad at communicating with shareholders. SOME of the silence I agree with, that has ALWAYS been my position. Personally I am confident all 3 patients are alive and well, I am confident P4 will be very soon and hopefully we will hear news about our first paediatric patient also. HOWEVER realistically how much will MDA or Hemo reveal about them? Historically not alot, but just imagine the boost to all of us and the company if we started to see some actual faces attached to these trials? Imagine the first adolesent is an avid streamer or tictoker and decides to tell the world about his miracle treatment when he thought he had no options. At some point one of the patients is likely to go public, With P1-3 I believe they were likely at the older end of the scale, less likely to divulge all on social media. Younger generations?

I HOPE PR ramps up, both internally and externally, I HOPE that its done organically, though Cellin being very loud to recruit when they finish the roll out to active patietns in the US trial just talking about their experience. But tht is not the same as attacking/shorting/trading a company working to save the lives of children, its not even close.

To your other point: "Dose them then initiate tech transfer while the safety and efficacy data on these patients matures."

You and Pumpkin STILL keep obsessing over this, Pumpkin is an idiot, you I believe know the answer but dont like it.

P3 was manufactured months before the treatment, as Vlad has made clear in interviews P3 did not meet protocol, they had to go to the FDA for amendment.

There could be no more patients selected without BDSM board approval, that could not happen without P3 passing the 14/28 day markers, that was blocked by an IND amendment which also probably had a 30 day wait. What you and Pumpkin are suggesting is that Vlad/Hemo had maintained the GMP certified lab an additional 3-4+ months with rent/maintance, an addional 10? Members of staff for those months on full pay but not running the trial? At a time when a small cohort of us has managed to raise enough money only for 1-2 months only to be decimated by a 40% discount II investment that decimated the mCap and wiped out headroom?

LETS BE CLEAR. NO. VLAD COULD NOT HAVE JUST DONE P4 and C1 THEN DONE THE TECH TRANSFER. The money that came in AFTER he started the Tech transfer from weathly shareholders WAS NOT ON THE TABLE UNLESS HE DID SO.

And I know there was a collection of sharks out there offering him £3m at £1 a share or less and that would have covered those 2 injections... MAYBE. But while it may have pleased you it would have decimated sharehoders and required an EGM.

At some point one of these patients hopefully will go public. A human face to the trial would be fantastic for PR.

Oh pumpkin.... oh you will not have to gate crash, lots and lots of people have expressed a great interest in meeting you. You will absolutely be invited.

Jezza you are new here so maybe you dont know the rules, talk like MRD negative is forbidden, optimistic posts banned. You will have 121, pumpkin, alde or not posting on your case, beware..... Unless you are one of the optimism police who decided to buy in....? God I hope not, I actually like your posts.

Perhaps vlad was sick of 121 trying to teach him how to suck eggs and decided to reply. Basically, back in your box, stick to power washing the abattoir and leave the science to the scientists 121. Vlad knows what he is doing.

No no no! 121 posted lots of convincing words, like lots of words about how it was better and Hemo was on the "old tech". I am going to listen to 121 and his unbias "keeping it real" I might even sell all my hemo and go all in on this AZ trial, i am sure it will bounce, 121 said so!

I reply to you to keep this fresh, I dont post for today, or yesterday, and I post now because you are here and engaging and I know you hear me. And Yep I know it will annoy others me replying to you so I will make this my last reply. I want you to know and believe that I am holding here and holding firm, I want you to know that I/we know your not.

I want you to absorb this to your core and keep it fresh:

When Hemo takes off, which it will, and soon, I will be sitting with a significant holding, MrIndia will be sitting with a massive holding, Haywain, HFH, the rest will be sitting with massive holdings knowing at that point that we won and you lost. We will probably all meet up and I can absolutely guarantee you we will be having a good laugh at your expense, at the hours, days, weeks you have spent trolling this share, this site. All for nothing.

So yea right now I am replying and "in your business" thats fair, but just remember this, when this takes off and none of us ever look back at LSE? You will still have a place in our heart, we will still be laughing at the sad pathetic 121 who blew his load on some dog share and is sitting at home stewing stinking of animal render as he prepares for another day of 9-5.

On that, to everyone else, have an absolutely fantastic weekend, I am feeling as amped and positive as ever, roll on next week! I have a good feeling the trials will be kicking into gear and news will start to flow soon :-) <3

I love it when you open your mouth 121 just re-enforces that your holding here is either zero or insignificant.

The unfortunate thing about the stock market is that its open to all, anyone can invest, but like sharing a public transport bus sometimes its full of trolls who dont shower and blast their music on speakers way too loud. Thankfully you make it obvious every day your just standing trolling at the bus stop and have not yet gotten onboard.

Before you go giving me abuse about attacking you etc, 100% from the bottom of my heart I am not attacking you, it is with the greatest of love and sincerity I say that I am extremely greatful to see you posting and confirming your position. Thank you!

121 every post from you reads like you dedicated your life to trying to spin Hemogenyx and everything they do as negativity as possible. You will be one of the few praying for the death of the first child i am sure but I would hope you have the decency to atleast keep it to yourself.

Your latest argument that HG-CT-1 might cost 100s of thousands to cure a patient? You completely and utterly deliberately miss the point that new treatments are always expensive, they get cheaper with time and its better an expensive treatment vs death. That being said, 200k is the likely price to start and that is a hell of a lot cheaper and safer and more effective than salvage therapy, than intensive chemo + bone marrow transplant whixg is the only thing that even comes remotely close for these patients. So yea.

We get it, you hate hemo, you hate vlad, you hate us, you wish the company would fail that patients would die that the company would go bust and we would lose everything. WE GET IT. Grow up and go away.

I 100% agree, his posts are demonstratably false and should be reported for misinformation, which is very frustrating as it wastes everyones time. The frustrating thing about it is he is not even posting anything that would encourage people to sell. The idea of a follow up dose etc might seem like a good idea to people, it may even seem logical that a half dose has limited durability etc. All this nonsense is not inherently bad or negative.

THE ISSUE IS ITS UTTER BS.

There is no "Half dose" the dose Cohohort 1 got is half of what the company believed would be the optimum dose but there is no follow up to "get the second half". CAR-T replicates in the body and in a target rich environment that lower dose for cohort 1 will have replicated and spread much faster than a full dose treatment. The starting dose just helps to get there faster, it does not in any way limit the ability of a lower dose to cure or help a patient.

This is not for dispute, this is settled fact, P1, P2 and P3 WILL NOT RECIEVE A FOLLOW ON DOSE OF HG-CT-1.

Now if anyone genuinely believes that 121 is really returdded enough to not grasp this then I have a bridge for sale, but I suspect he is posting this nose as rage bait. Some will say I have bit? Perhaps.

The reality is it does not matter.

121 clearly wants to distract and disrupt the board and put people off and rage bait IMO is a smart way of doing so and that is why I believe he is posting like this because in the past he has written coherent sentances.

Why???

Because he is not an idiot. He and others know that the Made transfer means that MDA and Made will stop prancing around like the new hire not knowing what to do, they will get on with the trial without the farceing about. Progress on HG-CT-1 will accelerate rapidly, and along side that Vlad is very likely to imminently update on Estonia, CDX and CBR. Traders like 121 will return, I guarantee it, twats like him dont post unless they have a reason and you only troll when you want to buy.

Tick tock - But now? there are many clocks ticking and not all are being wound by Vlad any more....

121, I have no idea what the hell has happened to you lately but your sounding like some strange mix of trump and putin in some fantisy distopian reality of your imagination.

You were telling us yesterday about how P1-3 were going for another dose, lets pause on that, because atleast you accept P1-3 are likely all alive and well which I can assure you means a MASSIVE green tick on efficacy and certainly for P1 meets and exceeds FDA longevity for this condition, add this to the fact that P3 had no detectable cancer left and we are looking at curative potential here which is mammoth. But setting that aside, NO, there is no follow up dose. Now your saying Made are still testing............ No Made are not still testing anything, THEY are contract manufacturers, they will take samples from a patient, they will process and produce CAR-T in sufficent quantity that MDA can administer whatever dose they wish. Made did their testing, they did their comparability studies and all was passed which is why we had an RNS saying tech transfer complete. Made have finished testing, they are now the CMDO for HG-CT-1 supplying MD Anderson for their clinical trial and any additional hospitals that may come online.

Your posts truly are worth calling out as more and more unhinged and whilst at one point you were illegible but had a foot in reality? Now I cant even say that :P

Think the key part of the Made transfer is the fact that it takes Hemogenyx out of the loop, I think even the most fanatic cult members here will accept that the Hemo timelines are as accurate and satisfying as a 2 year old drawing a sandwich on a 50 year old piece of newspaper. Vlad is an exceptional scientist and lately outstanding CEO but he has for years over commited and with the small team he has deadlines have been impossible for the company to meet.

FWIW I am very confident progress has been made in CBR and CDX and indeed in HG-CT-1 and estonia, but his team now is tiny and they have to focus, up until recently that focus was on Tech transfer, before that? The focus was on the trial and at that time focus on the trial for THIS team was incredibly inefficent and wasteful as you need the same size team for one dose vs someone like made who could be doing 100s of runs in parallel with multiple customers.

So where do we stand?

Hemogenyx are no longer the manufactuers of HG-CT-1, most of the staff and overheads associated with that are gone meaning the company have a fraction of the cash burn from 12 months ago. When MDA Select a patient that sample goes to Made who manufacture, test and return, Hemogenyx just pay per patient but are not involved in the manufacturing, they are no longer time constrained. That means speed should massively increase, reliability and parallel manufacturing for child and Cohort 2 are possible. Its going to be cheaper, faster and more professional and attractive to everyone including BP. Literally everything about this tech transfer is positive, the lackluster market reaction is irrelevant to the positive impact it has on the trial itself.

The big question then is what is Vlad doing right now? Tech transfer/FDA approval was never a blocker to CDX or Estonia, but likely Vlads time was. So what now? You can forget about the HG-CT-1 trial, that will now move forward at pace with a regular cadance with update etc unconstrained by Vlads limited capacity. But now in parallel Hemogenyx have a new found freedom, a time to catch up on everything that has slipped, we have a fairly good idea about what those things are and many of us are surprised there has been no update or progress yet, but now Vlad has the time perhaps we will see a more general acceleration of progress across the board.

My bed and Isa completed this morning so I am happy for news at any point now!

Im still waiting... feel free to sell Mr 1k seller >.<

Lol, np all good in the hood :-)

My god micky... no, you have been here for years and you should know what a bed and isa is. They sell 20k worth from your trading account and buy 20k worth in your isa, there is ZERO impact on the market and THAT is a fact.

Lol, moor, dw its bed and isa season, zero impact on share price, expect to see alot of 20k trades the coming weeks.

The excitement will come with p4..... or c1, either could be first and literally at any point.

Im shocked will aswell, but has to be done, but im with AJ Bell, although I placed my order today so should be near the front of the queue it could still take a few days, they say upto 10 working days but God I hope not.

£20k exactly:p