Member Info for Doc83

Yes, quite happy with the rise in recent days. Perhaps a hint of excitement ahead of Q2 and “a nice rich period”…

DocDaneeka - see notes below from the AGM on EUA. I've also included anther question regarding Platform trials.

QUESTION: What are the chances of getting onto a large Platform Trial and what are the timescales?
ANSWER: The chances are very high. Pursuing this as fast as possible and engaging with numerous teams around the world. Pretty much the whole Synairgen team is engaged in this activity as a matter of urgency. Can’t really give timescales at this point.

QUESTION: Is an EUA a pathway the company would consider or not?
ANSWER: SS (Simon Shaw) said this is extremely unlikely, with the focus on building as robust a case as possible for SNG001. It was, however, stated that if there was another variant which caused huge numbers of deaths then yes, an EUA could theoretically become more likely. But he reiterated an EUA was unlikely.

"Conclusions: SNG001 merits further investigation for treatment of COVID-19 in the home and/or hospital settings."

jonnygaddar - it's very likely some naughty broker switching a clients shares (or their own!) into an ISA at a cheap price, meaning more shares get inside the ISA.

Thornogson - Russia and China are allies and in cahoots with each other. My point being, Mongolia have to play ball with both and will almost certainly to some degree or other be controlled by these two nations.

As for me "appear(ing) determined to deflect talk and attention from the hopefully imminent issuing of Petro Matad's Land Permit for Heron", all we do is talk about the LP and what our SP estimates are! Good and refreshing to have something slightly different to respectfully debate, no?

"More importantly both Russia and China need Mongolia for the massive upcoming Russian gas pipeline connecting Siberia to China via Mongolia."

This is a good case in point. Imagine if relations soured and Mongolia said no gas can come through them... Russia would almost certainly invade them! So Mongolia have to play ball.

Thornogson - Matad will hopefully be competing against Petro China so I think it is important. But yes, right now it’s about the LP. Let’s hope there is no skullduggery going on and that it is as straightforward as cabinet signing it off. If it doesn’t, it could only be because of corruption now.

Thornogson - what planet are you on… Russia and China are each other’s closest allies?!

Not just that, but a population for Mongolia of 3.3m versus 1.7bn of their corrupt neighbours! I’m sure I’ll get shot down, but you have to be realistic and China/Russia will no doubt hold considerable sway of the Mongolia government.

TraderNick - SP is down 200p over last year or so and up 1p today! If it starts moving back to 20-30p, I’ll consider that a move up!

Shagged - I’ve said many times that my biggest concern is the fact Mongolia is a third world country land locked between two of the most powerfully corrupt countries on the planet. They will surely have agents there making sure their interests are being served.

“I recommend to keep supporting (and not filtering) WOS - even though some of his info is repetitive I consider it to be useful for the newbies and the forgettables (like myself).”

Staggered. Truly. WOS is PhilipTan and Magnus49. A known disruptor and ramper. Despicable historical behaviour.
Useful to newbies? You mean to get sucked in to believing this is a guaranteed, 100% dead cert with little or no risk?

Guys, it's basically still just on the spread. It did something similar the other day where it finished at 8.99p on the offer (bid was 7.5p or the like) and it flicked to a round 9p close.

Certainly nothing to get excited about.

Some unhappy comments on that Twitter post!

TipTop09 - you'll have to enlighten me. I can't see anything going on!

Here was for reasons for! Reading them, most are still applicable… I think someone did correct me on the 80% P3 success. I think that was for P3’s focused on respiratory viruses. The overall was a bit less if I recall, but still more often than not P3 trials succeed.

Reasons To Invest In Synairgen:

- Previous trial results, including advancement to phase 3 in ACTIV US trial, are supportive of a positive outcome.
- 80% of phase 3 trials succeed.
- Excellent management team who have worked on this for many years.
- Recent recruitment drive to senior positions.
- Science supports the case for IFNb.
- Ingredient is a naturally occurring protein.
- Broad-spectrum antiviral, already proven (in vitro) to work on multiple variants of Covid-19.
- Different to current crop of therapeutics (inhalation).
- Could provide basis for other treatments, Asthma/COPD etc.
- Brokers positive. Numis price target of £9.90, Dr Paul Cuddon experienced in covering such stocks. Finncap also positive.
- Omicron, an even more urgent need than ever before for a variety of therapeutics.
- Vaccine hesitancy, more people becoming disillusioned with vaccines. May need to rely more on therapeutics.
- Represents a good risk/reward bet.
- Polygon/Polar taking significant stakes in Synairgen.
- Finncap upgrade.
- Commercialisation agreement signed with Ashfield, owned by UDG Healthcare (former FTSE250 member before being bought out in 2021).
- Several senior job roles advertised focusing on the US.
- Synairgen Incorporated set up in the US post P3 data being received.
- Video from Synairgen on 17/01/22 saying “we’re ready”.

Badprophet, your screen must just be a sea of green boxes?!

This list?!

Reasons Not To Invest In Synairgen:

- Company is small and does not have the power/influence of large pharma.
- Chance of being the 20% that typically fail in P3.
- IFNb never been used in this way before. Could be some unknowns.
- Politics.
- Cost, with vaccines and pills cheaper.
- I own it.

Sadly, some of those turned out true.

Size82 - my best guess is that they have applied for strive and have been given a vague nod and wink. Hopefully busy writing up all the protocols and end points. The job advert for medical affairs director… boy, has that one got me stumped. Had that advert not been placed, I’d have been a bit more nervous. I really do hope they look after us PI’s, especially considering many stumped up for the P3 raise.

Yes, the only realistic way to avoid dilution is a free platform trial.

ParodyParrot - "nice to have a blue day for a change"

is that some dark humour?!