Member Info for Doc83

I've just had a small top up after listening to the interview. As WhiteKite says, at around 4:10 this is still "potentially a world class asset", "recent interest" re a JV with conversations behind closed door but currently active.

Plus there's lots else going on. It's a nicely diversified business.

Prof - I can assure you, I couldn't give t055 about your trading. Mostly because I don't believe you... always posting after the event... hmm!

Professional - perhaps tell us immediately after you have bought, and then immediately after you have sold. And even better, the number of shares so we can see it on the trade reporting screen.
Because saying something will fall on a certain date doesn't mean you bought in.

Prof - incredible how you always tell us about your trades AFTER the event. And how you never lose. You must have a net worth to rival Elon Musk.

Tomorrow would not be a good day for a positive RNS to land. So that's April gone and into May. Incredible how this year is flying by. So far, just a cash raise to pay MB's wages!

Prior to Covid, and going back some years now when RM was doing the rounds presenting at various investor meets, he always suggested that the aim was to ultimately sell out...numbers like £1bn for a P2 drug, £8bn for a phase 3 etc. (link below to such a presentation, 13mins in, slide 14)

https://www.youtube.com/watch?v=BzK7lCjN6Jw

At the AGM, chatting to RM and Bruce Campbell, they said it was about not panicking and making sure investors get what SNG001 is really worth. I don't see Synairgen taking the drug all the way to the end of another P3... rather, I reckon they are trying to make sure that it has the maximum chance of success if/when it does get on a P3, that will then make it very attractive for a BP to come in and offer good money.

The SP might be down today but I see support at this level because the financials weren't bad and there is a plan in place, albeit it's going to take a while. But of course there is also the possibility that we do get on STRIVE or another PT, as mentioned by them this morning - "Synairgen has been and remains in contact with the relevant platform trial investigators and will continue to evaluate options should they arise"

My big concern had been that PI's would get shafted somehow. Today has calmed those concerns somewhat. Questions that remain:

- What is going on with Polygon, are they insiders?
- What was the Medical Affairs Director job posting all about?
- What are those expensive senior hires doing?

The AGM can't come fast enough. They know they'll still be massive pressure on them, so have they held some good news back to drop in just before then?

4 green boxes in a row from my only filtered poster on LSE. What a sad, sad individual.

Ghia - out of interest, what would you have done as CEO of Synairgen? I promise I’m not being obtuse.

Where we are right now, today, I’m not sure they could have done more. I don’t think they can raise cash from here, but even if they thought they could, it seems there is still a chance of strive. I read it that they know there’s a good chance they’ll have to go it alone and these focussed studies are designed to ensure that when that P3 comes, they damn well pass it.

“Many of the platform trials that emerged during the COVID-19 pandemic have completed or wound down in part due to lower rates of severe illness or changes in funding. *Synairgen has been and remains in contact with the relevant platform trial investigators and will continue to evaluate options should they arise;* however, in parallel, wanting to move forward at pace, we believe that implementing our own current clinical development plan as quickly as possible will provide promising opportunities to collect appropriate and meaningful data to support an eventual regulatory submission.

This says to me they are still waiting on STRIVE or similar. But, as I said yesterday, it is prudent to continue forward assuming you won’t be on it. So they’ve put a plan together. I think a good one. They know they’ve got one last chance at this and the protocols and endpoints need to be bullet proof. So they are doing some focussed trials in advance of said P3 (how it’ll be funded TBC?!) to make sure they have everything right. I read registrational trial as wanting to go for approval if a P3 passed.

So in summary:
- Happy with the financial position.
- Pleased we are still potentially in with a shout of a PT.
- Pleased we are not relying on a PT and have set our own plan on motion.
- Relieved there wasn’t some negative curve ball thrown where we were being sold out to the devil for 9p, wound up or some other nonsense that would have stiffed PI’s that we never considered.

I have no idea what the SP will do. But hopefully it’ll provide some stability for a while, even if it remains around these levels.

I wish I could read assay results better, but looks a positive RNS?!

“We strongly believe that we are now in a position to significantly advance those conversations and set a course for the large-scale exploration programme that Molopo Farms”

Any comments from those more erudite than me?

“o Identified a clinical development plan for SNG001 designed to address the unmet need in targeted, high-risk patient populations that appear to be most responsive to SNG001 in previous clinical trials, for example elderly patients and those with certain co-morbidities.

o In addition, we plan to assess SNG001 in immunocompromised patients who are particularly vulnerable to respiratory viral infections, ventilated patients with confirmed viral pneumonia, and also those who appear unable to clear virus and become long term "shedders" and mutation hosts.

o Plan will start with a series of focused, investigator-led/Synairgen-sponsored studies, using existing resources, which are intended to lead towards a Phase 3 registrational programme. Preparation is underway for these focused trials to initiate in H2 2023. “

Cash position looks OK. Anyone care to comment specifically on that last point?!

Master - equally, you don’t have proof that LP is definitely going to land in the next few weeks, or that my September prediction is definitely not possible.

99% of the discussion on this board is the same old things being regurgitated over and over again. Especially from our resident ramper extraordinaire WOS. “Header say it all” and all!

Master, I’m not sure how many times I have to answer the same question.

Something can have a 20% chance of succeeding, but if it does, potentially 1000% upside. So good risk/reward.

I don’t want 6p. I want 15p, which I think is achievable if the LP ever arrives.

Even I thought back in December following the “my mining minister mate has told me 1-3 months from October” that we’d have the LP by now. But the continuing delays are highly concerning. I won’t be selling for now, because doing so and seeing it go to 15p would hurt me more than continuing to hold and it falling back to 2p.

MisterPositive: “Came across some ridiculous comments today. Cannot believe some people can be so dumb...

MG delaying LP till oil refinery is ready ?
And comment about people vote ?”

So that last point obviously aimed at me. But the fact is, the central government could have just bypassed the locals/local government already. It hasn’t. It has asked it to have another think. Why? Because it’s potentially a vote loser.

For me, while it might be 90% done that the central overrule the local government, it’s by no means certain.

IMO.

But of course, we’re not allowed to have an opinion on here if it’s remotely negative.

“The tax free UK 401(k)’s have been loaded up by Synairgen zealots causing the share price to rise by 70% to the 12p range”

Just for those who think this statement could be true, it’s not. I think he’s referring to those filling up their ISAs but there was a very sudden surge in volume on the 13th April at around 2pm that carried over into the next day. That won’t have been a load of random investors all deciding the load up their ISAs on that one day.

My guess - an individual buying up a lot of shares. Probably as a punt. But leaks do happen.

The MG are in uncharted territory. Overruling local government on what is clearly a very sensitive issue for said locals… I don’t think it’s as clear as the central government just overruling.

But I sincerely hope I am wrong and master et al are all right. Hell, I could do with a winner for a change!

Master82 - you seem to have taken a page out of iamrich’s foul mouthed vocabulary. You’re better than that scumbag of a chav, don’t lower your standards.

Regarding the Mongols, the people vote in the government. The government clearly want them on side, so is it so hard to believe this could drag on a long time yet if the government decide they’d rather the local people be ok with it and try to mediate?

ID - correct.

I’m in another stock (POW) and they churn out an RNS every week it feels.

"If the Mongolian government doesn't give LP, they can forget attracting foreign investors."

Maybe they (the majority of Mongols) don't want to attract foreign investment and like their country just as it is.

I think it's irrelevant if our cash position is £8m, £10m or £15m. We have enough cash to get by for another year, especially so if they start offloading some of the newer and expensive recruits.

The bigger issue is finding a path forward that involves trialling SNG001 again. If we don't have something by the time the existing cash pile runs out, it's likely all over anyway.