Member Info for D-Geeman

According to another BB I follow the LSE has a problem and no buying or selling on AIM stocks atm.

"I refuse to join any club that would have me..."

Wolf, I think (from my own viewpoint, still having too many shares for my own comfort) that you're correct the second time and it's just 'de-riskers' outnumbering 'in-for-a-punters' as the weekend bears down.

Thanks indeed Paul, for keeping us updated.

'For further inquiries:

Tiziana Life Sciences Ltd

Paul Spencer, Business Development and Investor Relations '

Pasting a link for Ticino that I've pasted before;

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7487063/#:~:text=FAP%20is%20known%20to%20be,%2Dassociated%20fibroblasts%20(CAFs).

These are some extracts:

'FAP in Cancer

While FAP expression in normal tissues is usually low or undetectable, it is overexpressed in many cancers, including 90% of carcinomas. FAP is known to be overexpressed in breast, colorectal, pancreatic, lung, bladder, ovarian and other cancers. In these cancers, FAP is usually heavily expressed in the stroma,'..

'Breast Cancer

While most studies confirmed the existence of FAP in the stroma surrounding breast cancer cells, one study identified FAP expression in the breast cancer cell lines themselves'

'Colorectal Cancer

In human colon cancer specimens, FAP expression has been identified in both cancer cells and in adjacent stromal cells, including myofiboblasts, fibroblasts and endothelial cells'

'Pancreatic Cancer

Ninety percent of pancreatic ductal adenocarcinomas (PDAC) demonstrate FAP staining. FAP expression has been identified in both the tumor stromal compartment as well as PDAC tumor cells and pancreatic cancer cell lines'

'Gastric Cancer

Gastric cancer consists primarily of two types: intestinal-type and diffuse-type. Both types express FAP, however intestinal-type does so to a larger degree. Unlike other cancers, in gastric cancer the majority of FAP expression is localized to the gastric carcinoma cells and is only weakly expressed in stromal and endothelial cells'

'In summary, FAP expression’s impact on clinical factors such as tumor type and clinical outcomes is highly variable and depends on cancer type, histological type, tumor localization and specific cellular expression (stromal vs. malignant cells).'

Polly,

'and we start the merry go round again at Itumbula.'

– it certainly all feels like 'it's-a-tombola' already...

Let's hope the brains at HE1 have interpreted the seismic data correctly and our tickets are going to get pulled out of the drum.

Fêted?

'TPDC and Helium were represented by Managing Director Mr. Mussa Makame and Helium One was represented by its Country Director, Mr. Fidels Lekule.'

I'm guessing Lorna is back in London and has been for a few days. No need for her to be at the meeting since they have Fidels Lekule but she might have popped in if she'd been near, or been photographed with the rig restarting (unless I missed that photo) over the weekend.

Sujood is just Michael Fish’s alter ego: "Earlier on today, apparently, a woman rang the LSE and said she heard there was a RNS on the way. Well, if you're reading, don't worry, there isn't!"

'when Avacta had veterinary'

'load of bull'

'not a one trick pony’

All these allusions to animals. Be a good (easy, early, and profitable) licensing deal for AVA6K into animal oncology before they have all the approvals for people.

I used to be able to smell jam when Greggs were baking doughnuts 1/4 mile away (before that site closed).

Really, the news of the drill resuming could come from anyone in the vicinity of the site.

Was going to say I like Icecool's open minded posts, but is that virtue signalling too??

'Looks like many expecting RNS Monday so taking positions... good move IMHO'

Yep, looks like there was a duplicate part on the van AND Mars bars are highly prized delicacy amongst Tanzanian elite..

There really has to be some sort of 'insight' (shall we say) if this rise is followed by genuine news. If it were influenced by the mood of the BB the sp would be falling not rising, on this occasion anyway.

'+3.37%'

Ok, so DPD left the part at the neighbour's place, and Noble swapped it for 1000 Mars bars (which weighed the same) before handing over the box.

HE1

Helium One Global Ltd NPV (DI)

4.50p

+0.22p +5.03%

So does +5.03% mean part just arrived? Part fitted?

Cheers Yeboha, I have a few dozen more shares now than I had first thing, based on a conversation you contributed to.

Tesla ' peaked at around $370 a share'.

Unless I am mistaken* Tesla shares were split into 10 to reduce the sp / share. So I think they went from $2.00 (your figure) to the equivalent of $2550 (your figure again).

I guess it shows what can happen with an undervalued company that becomes a success.

(*don't think so this time as I nearly bought some before the split, but went for Boeing instead :-(

Wonder how many Year 5 children asked their dad "how is Avacta doing today?" as they came out of the school gate just now? I know one.

# Maine Coon cat at £30.00

Strangy, I'm intrigued. Big birthday this year? 83 / 23. Maybe AVCT will provide an appropriate pressie.

Even though Wyn annoys you Strangy83, you don't filter him. Are you a closet believer? Nothing to be embarrassed about. I'm sure you're not alone :-)

At around 10 minutes in, Eliot Forster speaking on whether he'll get involved in a project, a company..

His "key bullet learnings" (though he elaborates some more):

"I have two rules now for"..

Rule number 1; "Do like the people I have to interact with?"

Rule number 2; "Do I think the technology or the drug or the idea is going to make a real difference to patients."

"If those two things apply then I’ll get into them"..