RE: Quick question2 Oct 2020 02:08
Yes antelope, that is exactly what they are saying, and it IS controversial. However, many academics have moved to the view that it is a justifiable risk in order to speed up the search for a vaccine, and potentially save millions of lives (1 million dead so far in 9 months, worldwide). There is obviously no antidote, otherwise the risk would not be necessary, but the antiviral drug remdevisir offers some relief in some cases. Only healthy young people would be infected, and the mortality rates in the younger age ranges are extremely low (but NOT zero). My understanding is that the study CF was offering to volunteer for was different - not for full blown COVID-19, but using a modified strain of another less harmful coronavirus to mimic the relevant elements of COVID-19: therefore essentially risk free. CF will certainly not be volunteering for the human challenge trials, and is anyway probably too old. If they get the go-ahead, the trials will probably run in parallel (timewise) with the final phase 3 tests of the leading vaccine candidates. It is only when a vaccine is actually released to the general public that it's true impact on a population can be fully assessed, which is why exhaustive testing is essential before that momentous step, and why human challenge trials can potentially speed up the process compared to testing on artificial substitutes.