AVCT:-10 Dec 2018 08:26
Yearly high is over 70p.
Collaboration agreement with LG
Headlines
The Affimer therapeutics development collaboration with the multi-national, multibillion-dollar group, LG, represents a major endorsement of AVCT’s Affirmer technology platform. LG is a strong partner, and its wholly-owned pharmaceutical subsidiary, LG Chem, has a track record of being able to develop new biopharmaceutical drugs all the way to commercialisation. The first part of this deal would entitle AVCT to receive up to $180m in upfront payments and milestones, which falls within the normal range for access to such assets and is particularly good
for a platform that is yet to be validated in man, event expected to happen in 2020.
In return, LG receives the exclusive rights to develop and commercialise, on a
worldwide basis, multiple Affimer molecules in two therapeutic areas:
? inflammatory disorders; and
? oncology
Under the terms of the agreement, the collaboration is segregated into three stages:
? Step 1: AVCT to generate Affimers and carry out the discovery, optimisation
and protein engineering of Affimer drug candidates against a number of
undisclosed targets.
? Step 2: LG and AVCT to collaborate to progress these candidates through to
drug candidate selection.
? Step 3: LG to be responsible for the pre-clinical and clinical development, and
worldwide marketing of any resulting products.
Moreover, LG has the option to add further targets and, if the option is exercised, AVCT will be entitled to receive up to an additional $130m in fees and milestone payments. This values the whole agreement at $310m.
LG Chem Life Sciences is a business division within LG Chem, itself part of the LG Group. LG Chem was founded in 1947 and is now the leading chemical industry in Korea, with more than 29,000 employees and annual sales totalling KRW25.7 trillion ($23bn/£18bn). It is engaged in the development, manufacturing and commercialisation of pharmaceutical products globally.