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I've been in here since early April. Astonished and utterly dismayed at the long, long, shameful wait to get governments to pay attention to what was a no-brainer even then.
Now finally it's urgent in both UK & US. Phase III trials started in UK 13th Jan.... WHEN WILL WE GET NEWS? ie When will they start to save lives on the larger scale? It was to be spread over "approximately 20 countries" and involve 610 patients, and it's now nearly 2 months on. Supposed to be urgent, now it's 48 days in, over 20 countries (what were they thinking of?).... that's less than 1 patient per country per day. 0.635 to be precise. What has been the blockage all along? They were to be hospitalised Covid patients requiring oxygen. Surely not too hard to find in a global pandemic!!
The 13th Jan RNS re the UK et al phase III trial also stated "Synairgen is also running an ongoing Phase II trial of inhaled interferon beta in non-hospitalised 'at risk' patients, (SG016), that is progressing rapidly. For more information and to take part, visit www.covidtrialathome.com." Recruitment completed - the last patient recruited - on 20th Jan with much fanfare, but "Results from the trial are expected in Q2 2021." OK, maybe there is much, much that I don't understand that has to continue, including ongoing monitoring, but these are at home non-hospitalised patients, surely within a couple of weeks you are already seeing results, or not. All along the lack of urgency has been terrifying.
As Prof Francis from Southampton Uni stated "Following the promising results from the SG016 Hospital Study, we are excited to see whether we can detect important benefits from early use of inhaled interferon beta (SNG001) for COVID-19 in the home environment, in terms of resolution of symptoms, preventing hospitalisation, and reducing the burden of Long-COVID." Only the last of these takes time, and can be ongoing...for years...so why hold up the other sides when lives are at stake?
The US trial - redoing Phase II because no one else can do anything competently - started 15th Feb. HOWEVER "If an investigational agent shows promise by demonstrating safety and reducing COVD-19 symptoms through 28 days following administration, the ACTIV-2 trial is designed to expand seamlessly from a Phase II to a Phase III study to gather additional critical data from a larger pool of volunteers without delay."
Which means that in a couple of weeks it's possible we might get news that the trial has been expanded direct to Phase III, which will be an enormous fillip. More likely later, due to recruitment, as always.
Rant over. For now! But the delays on this have been simply incredible to me.
As a shareholder I'm encouraged that according to Stockopedia the last time a major shareholder sold down was last July, while since October Polar Capital, Axa Framlington, Chelverton, Jupiter and Southampton (?) have all bought in or increased their stakes.
Qd22
" All along the lack of urgency has been terrifying.".
You've done no research, that much is clear. Alternate agenda.
Bore off.
Qd22
Your rant not to dissimilar to my rant a couple of days ago and is perfectly understandable The wait has been torturous and more agonizing when thinking of the lives that could have been saved Hoping that news will arrive before the Ides of March
ATB
Sweden heading into 3rd wave of lockdown.
Sweden? You sure, I thought they didn't adopt lockdown startegy through the pandemic?
Q22,
I believe big pharma are behind delays / Authorisation. This should already be in use, 15 years data against untested vaccines, FFS!
How many loves could have been saved.
Fortunately I believe RM to be ticking every box to make synairgen 100% watertite.
Thin. Check the news.
https://twitter.com/J18691375/status/1366804758464503813?s=20
just have, this shows we are far from the end of the pandy, a country that up untill now didnt lockdown is now locking down. speaks volumes
I really don't and won't blame the company here on this.
Let me state my position here for people who will think I'm a deramper. I have 25% of my total wealth invested here. For a long time I have been convinced this has been suppressed. I just cannot believe in the current **** show this isn't being administered as the go to drug.
The link below is a video in which a journalist, Dr. And a group supporting it discuss a drug that is extremely safe and has proven results. His paper which was peer reviewed numerous times has been pulled with no explanation.
People will dismiss this as conspiratorial etc. I dont think it is and it is certainly worth a watch when we are all waiting patiently on results and news.
https://youtu.be/qP36UgVjMPk
If this stuff is going, unfortunately I don't think anything is as nailed on as I previously thought even though it should be.
Czech Republic taking a beating as well Doc. The Russians are supplying their Spucknik vaccine.
Also snippets of ground news coming out of Israel, but cannot clarify yet. Word is, vaccine is not as good as planned. As mentioned trying too find out more.
Atb
Migmcl86,
I share your sentiment, the agenda is pump untested vaccines at all costs.
Reminds me of David Noakes and Gcmaf.
Not into conspiracy theories Doc. What I am interested in, is scientific data.
Talking of conspiracy 60% of Russians are refusing the Sputnik vaccine. A great majority of Russians believe coronavirus a biological weapon. Source US News.
interesting
Doc, Israel doesn’t count, they were under lock down and aren’t exposed to any other strain... let them open everything and let foreigners in and then we will see where these numbers will be..
It's tough working out the media news streams. For example, the media were saying over the weekend Germany was preparing for 3rd lockdown. Reuters have just announced Germany planning to reduce lockdown measures.
Israel still have a lot of people in hospital suffering from coronavirus.
My only conspiracy thought is vaccines aren't the silver bullet that we are told to believe.
Good evening all
Good luck with your investment Dumbpunter.
I believe Germany have extended the national Lockdown to March 28th but have announced plans to ease the lockdown in areas where there is a lower prevalence of the virus.
Yeah I listened to it myself today and thought it woukd be if interest to people. Although it's not the drug we are invested in it gave quite good detail for the layman so to speak.
It just made me less optimistic for the speed that we might see SNG in use.
What really spiked my interest was the piece on the Bill and Melinda Gates foundation work regarding ivermectin. Leaves me more cynical on it all!
Migs. No disrespect, I see you like crypto currency. How people can invest in nothing more than a gamble, with no true foundations or fundermentals is ridiculous. The lastest crypto currency boom is incredious. It will end in tears.
Atb
Woodstock i fear that IF central banks go with negative interest rates, then anyone with any little amount of saved cash, will either put it under their mattress - as in years passed, or buy crypto. I sincerely hope that the seeming insanity of negative interest rates never comes home to roost in the UK
I dont like crypto currency at all. I havent invested in any of it. Just because I think digital currency might come doesn't mean I like it for a second. I see it ending in disaster myself.
great read its all coming together
Woodstock - Crypto is just as baseless as FIAT currency. It’s all a matter of perspective gold only has value because it’s finite and people like it.
If people didn’t like or want gold it would have zero value regardless of how scarce it is.
The power of crypto has yet to be realised by the masses.
Currently if I want to buy a house I need a bank and a solicitor to act as intermediaries to ensure both sides of the party hold up the deal.
In the world of crypto you don’t need a bank or a solicitor since the network verifies the transaction.
Crypto will make so many processes more efficient and safe but it will displace the need for lawyers, solicitors and the banking system so sadly it might take a while.
Bitcoin whilst the first crypto currency is not the future. Services built around the etherium token are the future.
CDC director says the United States covid battle is likely to be hindered by The new varients. Source People.Com.