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Valirx Share Chat (VAL)



Share Price: 0.525Bid: 0.50Ask: 0.55Change: 0.00 (0.00%)No Movement on Valirx
Spread: 0.05Spread as %: 10.00%Open: 0.525High: 0.525Low: 0.525Yesterday’s Close: 0.525


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borgie
Posts: 440
Opinion:No Opinion
Price:0.525
Anybody
Today 11:12
Thought if having a meeting with our esteemed Chairman. It's a while since he had anything useful to say.
 
ValJu
Posts: 6,172
Opinion:No Opinion
Price:0.525
RE: pledge
Today 11:12
Diplomacy works both ways... in other words, we shouldnt be having to go to the BoD, they should be coming to us... ?
ValJu
Posts: 6,172
Opinion:No Opinion
Price:0.525
RE: pledge
Today 11:09
With all that is currently going on and an imminent agm due? Do you really think they would want to currently?

Knowing, that I would have to liase with 41 Pledgers and then select say two or three and again, decide on the key two or three questions, from the many and then would that put me inside and then unable to act accordingly ?

Im only suggesting what has been asked of me by other Pledge members ?
borgie
Posts: 440
Opinion:No Opinion
Price:0.525
If 201
Today 11:06
JV partners. End of rant.
borgie
Posts: 440
Opinion:No Opinion
Price:0.525
If 201
Today 11:03
bloody works now is the time to prove it. The headroom left will not raise enough cash to see Val through to the end of the year which is when we have been told to expect results. Read the last rns on 401 and the Hardman report. No cash is coming to Val until the next trials are complete. Only knowing the quality of the LV partners will give the sp a boost. You think a quiet chat with GM is going to solve that or are you going to approve more headroom at the AGM
borgie
Posts: 440
Opinion:No Opinion
Price:0.525
Uncanny
Today 10:55
If you are a lth then do you think anything is going to change George's mind after all he has said about lths in the past. You saw what happened to Align. Diplomacy did not work there. If you had a meeting tell me what you would ask.
Uncanny
Posts: 1,361
Opinion:No Opinion
Price:0.525
RE: pledge
Today 10:50
I agree Shirley, diplomacy not aggression is more constructive.
shirleyfraser
Posts: 414
Opinion:No Opinion
Price:0.525
pledge
Today 10:45
in fairness we went to the board at solo oil and that changed there minds completely an in the end ceo stood down, im only asking these questions but fully respect othere s points of view and the hard work some members here have and continue to put in
borgie
Posts: 440
Opinion:No Opinion
Price:0.525
Uncanny
Today 10:33
It may be that the directors standing at the AGM for re-election do not get elected and it may be that if more headroom is asked for at the ,AGM it may be voted down. Have a plan Uncanny. Take your point SF but all they have to do is release updated PSA levels for the cohort before the one being tested. All we have so far is the original cohort readings and hints of later tests but nothing substantial. At this late stage patient confidentiality will not cut it. A meeting would not help as all they would give would be the same as that given by Satu and that did not help the sp. All very well for the bod to say 401 negotiations being done by Valiseek but no chance of an rns from them. So a plan is required.
ValJu
Posts: 6,172
Opinion:No Opinion
Price:0.525
RE: Pledgers Easter Update
Today 10:21
Join the Pledgers group, and you will know?
shirleyfraser
Posts: 414
Opinion:No Opinion
Price:0.525
pledge
Today 10:18
valju , morning all, only my thoughts and good to have plan a,b,c etc, but do you think its not worth contacting the bod and ask for a meeting to discuss our concerns and what action we or any others would like to see taken ? before any other action by ourselves is taken?
Uncanny
Posts: 1,361
Opinion:No Opinion
Price:0.525
RE: Pledgers Easter Update
Today 10:17
War chest for what exactly?

TIA
rightback
Posts: 4,465
Premium Chat Member
Opinion:No Opinion
Price:0.525
RE: Pledgers uodate
Today 10:12
Valju
I am also ok with that figure.
borgie
Posts: 440
Opinion:No Opinion
Price:0.525
Pledgers uodate
Today 09:53
Great post Valju I'm in. Will contact you direct when set up. I suggest this is done well before the AGM to have the firepower ready.
ValJu
Posts: 6,172
Opinion:No Opinion
Price:0.525
Pledgers Easter Update
Today 09:46
It was put to me, by several pledgers during the weekend, to start the accumulation of a "war chest" ie raise the 30k at £300 per million shares held or part therof...

Can I get a general consensus of opinion, as if the figure is acceptable?

Please Email me direct, with your thoughts and please note - funds, would go directly to solicitors account, not myself! and only used, by prior agreement of all contributors...

Of course, by all means like and comment should you wish to...

As those that suggested this... say, it is best to be prepared, in advance?

Thanks VJ
Obelix
Posts: 11,870
Opinion:Buy
Price:0.525
Guys
Today 09:29
Good morning to all here,
I hope you Guys have had a good relaxing weekend.
I just hope our BoD release news about this agreement very soon (possible this week) and we all here will finish with negativity about placing and scare new investors.
We are closing to our rewards, but many of us (include myself) still not happy with BoD Management and lack of PR
Hope all this change very soon.
Have a nice day all, take care.
Obelix
Uncanny
Posts: 1,361
Opinion:No Opinion
Price:0.525
RE: From Here AIMOO
Mon 17:43
Quite right Noise.
101 early days but shareholder value in 401 commercialisation (8 figure total package for SEEK and VAL) and 201 that gets the fluids boiling, so to speak!
As you say, May could be an exciting month as investors position themselves for a repeat to December 2017.
Why would we get all the hype on 201 pre-close on CTl/ll just to disappoint!
Its funny how all the doomsayers come out of the woodworks when we get close to an epiphany for VAL in its fortunes.
LTH’s have suffered by the dilution which is enviitablel, but thats the nature of junior bios until they get to fruition point.
This why its worth waiting for news and the story to unfold:
https://www.cnbc.com/2018/08/02/why-ronald-wayne-sold-his-10-percent-stake-in-apple-for-800-dollars.html
Noise
Posts: 3,043
Opinion:No Opinion
Price:0.525
RE: From Here AIMOO
Mon 13:50
CAR-T should be available for late stage cancers within 5 years, assuming no big surprises. I'm not sure it'll be the best first-time treatment option for hormonally driven cancers, androgen blockers, surgery and potentially val201 would strike me as better options. Val101/bcl2 regulators could be interesting, but alas I have no idea wth is going on with val101, it is a complicated compound and I guess Val haven't quite had the funds to push it much recently.
nomlungu
Posts: 2,913
Opinion:No Opinion
Price:0.525
RE: From Here AIMOO
Mon 12:24
I Spy,

I do not view VAL201 as 'old hat'. Funding for further trials of the drug will have been hampered by the hype around CAR-T therapies but that hype has died down and the share prices of many immunotherapy drug discovery companies have slumped, and with that the funding that could have gone towards their trials is more likely to be available trials by companies such as Valirx.

CAR-T therapies have had limited success treating solid tumors - any drug that can slow tumour growth and reduce metastasis (which is what the VAL201 trial is attempting to prove) would be well received by the market.

My post was just a response to the post about a 20 bagger from VAL201 and wondering if there was some research that I was missing.

Despite what some may think, I would like to see progress with Valirx's compounds for both Cancer sufferers as well as the shareholders. I may well end up buying shares here again once funding is clearer.
Uncanny
Posts: 1,361
Opinion:No Opinion
Price:0.525
RE: From Here AIMOO
Mon 10:34
Noise
CAR-T is a decade away as you say.
Why do you think we suffer the daily barrage of de-ramping attackers on here and ADVFN?
Because VAL’s compounds are a serious threat to various other small bios products because VAL are so close to commercialisation and this gives them brown underpants.
LOL
Hoping for more LoI for 401and extremely excited at the next 201 update.
Noise
Posts: 3,043
Opinion:No Opinion
Price:0.525
RE: From Here AIMOO
Mon 10:09
I see CAR-T as a later stage treatment for the next 5 years or so. Autolus have some interesting trials with fast off switching that could improve industry confidence with it (historic trials with CAR-T solutions included some serious side effects).

I think nomlungu may be academically correct with the protein Vs peptide argument, but it would still have to progress through pre-clinical studies and I'm not aware of a protein version of 201, so that would take 5-10 years of playing catch up?
IsleworthSpy
Posts: 688
Opinion:No Opinion
Price:0.525
RE: From Here AIMOO
Sun 17:51
@ nomlungo.

For clarity: Are you saying that 201 is old hat? That there is no place in the market, despite the apparent developmental success, as released in recent RNS's?

Excellent links by the way. But it would seem that CAR T therapy is not a one cure for all cancers.
All IMO by the way, as a humble postie. And I do stand to be corrected.

I Spy
nomlungu
Posts: 2,913
Opinion:No Opinion
Price:0.525
RE: From Here AIMOO
Sun 16:43
Another Uncanny post...

From VAL's website:

'The Company’s business model focuses on out-licensing therapeutic candidates during the development process'

You may hope that they sell VAL201 'upfront' - a bit like your comment a few days ago about the 2 large trades; hope and reality are distant cousins.

VAL201 is a Peptide solution but current science is moving to Protein solutions.

https://www.youtube.com/watch?v=Mt5C5fhuU_0

https://www.genscript.com/protein-antigen-vs-peptide-antigen.html?src=leftbar

The first link is from the UCL Biomedical Research Centre about CAR T-Cell therapy; the second from Genscript Biotech. The animated video is worth watching.
Uncanny
Posts: 1,361
Opinion:No Opinion
Price:0.525
RE: From Here AIMOO
Sun 15:36
If they sold 201 upfront, that would be a minimum nice 20 bagger!

I hope they do tbh.
Dracula1
Posts: 654
Opinion:No Opinion
Price:0.525
Lets Hope
Sun 15:14
That It'all good and soon Noise we're due a bit of positivity on the SP front. Not certain but FWIW I THINK that times up for some of the Warrants In May.. Hardly a reason to withhold results until then though.




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