Proteome Regulatory News (PRM)

1 Apr 2008 15:20

TR-1: NOTIFICATION OF MAJOR INTERESTS IN SHARES 1. Identity of the issuer or the underlying Proteome Securities Plc issuer of existing shares to which voting

rights are attached:

2. Reason for the notification (please tick the appropriate box or

boxes) An acquisition or disposal of voting rights

Yes

An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are

attached

An event changing the breakdown of voting rights 3. Full name of person(s) subject to the Cubana Investments Limited

notification obligation:

4. Full name of shareholder(s) (if different

from 3.):

5. Date of the transaction (and date on which 01 April 2008 the threshold is crossed or reached if

different):

6. Date on which issuer notified: 01 April 2008 7. Threshold(s) that is/are crossed or reached: >8%

8. Notified details:

A: Voting rights attached to shares

Class/type Situation previous Resulting situation after the triggering of shares to the Triggering transaction transaction if possible using the ISIN CODE Number of Number of Number of Number of voting % of voting Shares Voting shares rights rights Rights Direct Indirect Direct Indirect

GB0003104196 10,374,272 10,374,272 10,531,272 10,531,272 10,531,272

8.01% B: Financial Instruments

Resulting situation after the triggering transaction

Type of Expiration Exercise/ Number of voting % of voting financial date Conversion Period/ rights that may be rights instrument Date acquired if the instrument is exercised/ converted N/A N/A N/A N/A N/A Total (A+B) Number of voting rights % of voting rights 10,531,272 8.01

9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable:

N/A Proxy Voting: 10. Name of the proxy holder: N/A

11. Number of voting rights proxy holder will N/A

cease to hold:

12. Date on which proxy holder will cease to hold N/A

voting rights: 13. Additional Information Contact name: James Malthouse Contact Telephone number: +44 1932 865065

Note: Annex should only be submitted to the FSA not the issuer

Annex: Notification Of Major Interests In Shares

A: Identity of the person or legal entity subject to the notification

obligation

Full name (including legal form for legal Cubana Investments Limited

entities) Contact address (registered office for PO Box 957, Offshore Incorporationslegal entities) Centre, Road Town, Tortola, British Virgin Islands

Other useful information (at least legal representative for legal persons) B: Identity of the notifier, if applicable

Full name Mirza Rahman Contact address 2 Battery Road, #26-01 Maybank Tower, Singapore 049907 Phone number +65 65381998 : msrahman@artradis.com

Other useful information (e.g. functional Compliance Officer relationship with the person or legal entity subject to the notification

obligation) C: Additional information