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With Numis on board Synairgen are now playing in the big leagues. Definitely seems like we got some big news incoming.

Definitely looks like something big is about to happen. Very exciting indeed.

Sounds like he needs a little SNG001. No matter what you think of the (orange) man, the fact the even the President of the US has gotten infected will increase the the demand for therapeutics. Synairgen have gotten on the market just in time.

https://www.google.com/amp/s/amp.cnn.com/cnn/2020/10/01/politics/hope-hicks-positive-coronavirus/index.html

Moderna's vaccine not being ready until Q2 2021:

https://www.google.com/amp/s/amp.cnn.com/cnn/2020/10/01/health/moderna-coronavirus-vaccine-bancel-bn/index.html

And the FDA broading it's investigation into Astrazeneca's vaccine:

https://www.ft.com/content/2356aa1e-b862-405d-be41-e64ee14b41ba

It certainly doesn't bode well for anyone expecting a vaccine to come along and save the day.

Even if all the vaccines were ready today the distribution would require 8000(!) special medically fitted JUMBO JETS as the vaccines need to be stored between 2 and 8 degrees. I think anyone can see a big problem there. And the reason we won't be seeing a readily available vaccine anytime soon.

https://www.google.com/amp/s/www.cnbc.com/amp/2020/09/10/coronavirus-vaccine-8000-jumbo-jets-needed-to-deliver-globally-iata.html

That's why SNG001 is the best and most effective treatment to back.

And now it's on the market generating both income and critical safety data.

It's not even ramping to say that it is hard to even imagine the potential here in both saving lives and investment return.

And to think that COVID-19 is just one of many uses for this drug is staggering to say the least.

Of all the shares I have been involved with this one is to me the safest return of them all due to the many, many legs SNG001 has to stand on. When the next virus' come along, and people start scrambling to create new vaccines, SNG001 will already be ready for use. That in itself is simply insane. So glad to be a small part of this.

GLA and have a great Friday!

A lot of big buys coming through. Clearly big things building up here. Certainly excited about Friday and the following week. All go for SNG001 globally and the positive data from France and Europe will come quickly. Synairgen are making money now with plenty in the bank already. It certainly bodes well for the SP and our investments. Guess I should say it...I wouldn't want to be out of this over the weekend ;) GLA

https://m.youtube.com/watch?v=SaolVEJEjV4

260000*

Here are just a couple of new pandemic virus' potentially on the way and SNG001 is already prepared to stop them unlike anything else on the market:

New swin flu pandemic:

https://www.medscape.com/viewarticle/937422#:~:text=Pig%20farmers%20in%20China%20are,IDSA)%20news%20conference%20last%20week.

"Unfortunately, this influenza strain has all the attributes to cause a pandemic"

"It is easily taken up by human cells"

"Is more virulent and more infectious and has a worse outcome than human influenza A"

FYI the flu alone kills between 26000 and 650000 people a year.

There are also reports of a new H7N9 virus on the way with a "high mortality rate".

SNG001 is so important and needed that it is borderline rediculous.

The coming weeks, months, and even next year are looking brutal for the world.

Thankfully SNG001 is able to stop it all according to the data. Just wait until the positive data starts literally pouring in now that it is on the market. Boris will be scrambling to climb on board. Onwards and up, Synners.

Record new infections cases, deaths, growing hospital admissions, and now a sudden growth in confirmed reinfections with some considerably worse the second time.

This is just the beginning as the world enters the winter months and flu season in - rather startling - a much worse state than before the first wave of this pandemic.

https://bnonews.com/index.php/2020/08/covid-19-reinfection-tracker/

https://www.lancashiretelegraph.co.uk/news/18760690.coronavirus-long-winter-ahead-hospital-admissions-rise/

https://www.google.com/amp/s/www.nytimes.com/2020/09/15/opinion/coronavirus-precautions.amp.html

https://www.thedailybeast.com/british-scientists-warn-covid-is-spiralling-out-of-control-again-and-london-isnt-immune

This shows a few things:

1. This virus isn't weakening or going away any time soon, sadly. It will be with us next year as well regardless of vaccines.

2. Any thought of post covid 19 immunity or immunity due to vaccine is off the table. Vaccines or immunity are not going to stop this. Even the WHO say this now. So even with a vaccine SNG001 will sell like hot cakes.

3. The answer to this pandemic lies with proper safety guidelines and, most importantly, therapeutics.

4. SNG001 is the best therapeutic with the best recovery percentage (79%) and fewest side effects by far.

5. Unlike any vaccine in development or current treatment - SNG001 is ready for the next virus', flu, MS, ARDS, COPD etc with, again, fewest side effects by far in comparison to any other treatment. In other words it has an enormous market value beyond even this pandemic.

6. The growing scientific consensus is interferon beta-1a is the answer and SNG001 with it's patented nebuliser form and use with steroids is the safest of all interferon treatments.

Now it's on the market and Synairgen will not only be getting an enormous amount of data - they will also now be getting paid which means this company is now on the fast track to new highs. And I'm very pleased to be part of it.

Just remember that Rebif and Avonex - the two IV interferon beta-1a treatments - had combined sales of 5.51 billion dollars in 2013. SNG001 is more effective and has fewer side effects by far. That alone makes me very comfortable and confident with this investment.

I hate to use the term but this really is a 'hold for gold' situation, in my eyes.

Have a great day everyone!

I had to have another big top up myself at 144. The opportunity here is far too good to pass up. Especially at these prices. A lot of updates incoming including the peer review which is due any time now looking at the timeline.

I can't believe my luck to get more at this price after those RNS'. Very pleased

It has happened to every stock that got good news today. Just the day traders selling. Now it can go up again.

The day is young and now we have the stepping stones in place for a nice climb up!

I agree completely. Plenty of money in the bank and sales happening. To think there is even bigger news on the way is incredible considering how good this news is. Finncaps suggestion that the share price "will go significantly higher" is looking pretty good now.

Well said, benbenbenben. Looks like a real nice climb from here. Exciting times ahead.

Same Dumbpunter :)

Interim results as well:

Synairgen plc

('Synairgen' or the 'Company')



Interim results for the six months ended 30 June 2020





Southampton, UK - 29 September 2020: Synairgen plc (LSE: SNG), the respiratory drug discovery and development company, today announces its unaudited interim results for the six months ended 30 June 2020.



Highlights (including post period-end)



Operational



· Positive results from SG016, its double-blind placebo-controlled Phase II trial of SNG001 in hospitalised COVID-19 patients announced in July



· The Company extended the SG016 Phase II trial to include a further 120 patients with confirmed COVID-19 to be dosed in the home environment (ongoing)



· Positive results from interim analysis of SG015, its double-blind placebo-controlled Phase II trial of SNG001 in COPD patients announced in September, supporting the COVID-19 programme



· Patent applications for SNG001 in COVID-19 patients and in exacerbating COPD patients undergoing treatment with systemic corticosteroids were submitted post period-end



· Synairgen launched a Managed Access Program with Clinigen, to provide SNG001 to hospitalised COVID-19 patients - see separate announcement issued today



· The Company is currently in discussions with regulatory agencies to establish the route to approval of SNG001 as a treatment for COVID-19



· The Company is also investing in supply chain activities to ensure that drug and aerosol delivery system availability can meet potential demand, pending approval



Financial



· In March 2020, Synairgen raised £14.0 million (before expenses) in an equity issue to fund its initial COVID-19 related activities and strengthen its balance sheet



· Research and development expenditure for the six months ended 30 June 2020 was £4.47 million (30 June 2019: £1.69 million) as the Company advanced its clinical trial of SNG001 in COVID-19 patients and scale-up activities



· The loss from operations for the six months ended 30 June 2020 was £5.08 million (30 June 2019: £2.21 million loss)



· Cash balances of £10.9 million at 30 June 2020 (30 June 2019: £3.52 million)



Richard Marsden, CEO of Synairgen, said: "The first six months of this year have been the most significant in Synairgen's history. We were delighted to announce positive results from our hospital-based COVID-19 trial in July, and have been working tirelessly on the progression of SNG001 as a potential treatment for COVID-19 patients. With further positive results from our interim analysis of SNG001 in COPD announced in September 2020, we feel well-equipped to realise our strategy of progressing inhaled interferon beta for the treatment of respiratory viruses. I'd like to thank everyone involved in the Company and trials for all their hard work to date."

We finally got news and it looks great!

Synairgen and Clinigen sign Managed Access Program agreement with SNG001 for treatment of hospitalised patients with COVID-19



Southampton and Burton-on-Trent, UK - 29 September, 2020: Synairgen plc (AIM: SNG, 'Synairgen'), the respiratory drug discovery and development company and Clinigen Group plc (AIM: CLIN, 'Clinigen'), the global pharmaceutical and services company, have signed an agreement to launch a Managed Access Program for Synairgen's inhaled formulation of interferon beta
(IFN-beta), SNG001, in the UK and the EU for the treatment of hospitalised COVID-19 patients.



SNG001 is an inhaled formulation of IFN-beta for direct delivery to the lungs via nebulisation. Synairgen announced positive topline data generated from 101 patients hospitalised with COVID-19 in its phase II trial, SG016, on the 20 July 2020. The trial of SNG001 in hospitalised patients produced very encouraging findings; patients who received SNG001 were more than twice as likely to recover over the course of the treatment period compared to those receiving placebo. Synairgen is currently in discussions with regulatory agencies to progress this potential COVID-19 treatment.



Richard Marsden, Chief Executive Officer of Synairgen, commented: "We are working tirelessly to progress SNG001 through the required clinical and regulatory channels to make this potentially critical treatment widely available to COVID-19 patients around the world. In the meantime, we are delighted to partner with Clinigen, whose extensive European experience and regulatory expertise will support access to treatment with SNG001 for hospitalised patients who most urgently need it."



Shaun Chilton, Clinigen Chief Executive Officer, added: "We are working with a number of companies who have products being tested against COVID-19 and are very pleased to be working with Synairgen to make this highly promising COVID-19 treatment available internationally. The early study results demonstrate that SNG001 may have a vital role in helping hospitalised patients recover more quickly from the disease."

Morning all! Hope everyone had a good weekend. I just finished work after pretty much nonstop since Friday so before I go into a work induced coma I gotta say that news about interferon beta-1a has spread like wild fire in the health sector. A couple of months ago I could barely find a single person who knew about interferon beta-1a. This weekend, however, it seemed to be all people were talking about. I had several people approach me about it and even got a work email about it's effects. News about this is growing quickly and every bit of science is backing it up. Lots of great nuggets in here as well I see over the weekend. Exciting times ahead especially that we are now in the annual 'results week' for Synairgen. I also see that Synairgen are favourites to win the AIM awards which certainly would raise awareness further for this great company. Looks like Hold might have to abandon the yak farm and return on a sea of blue from the SP. Have a great week everyone!

Wed

Had a big top up this morning as well after many tries. Very pleased. This investment looks better every day. Thank you all for the great research. Have a great day everyone. I'm off to work. I look forward to the day I can have some SNG001 with me.