Member Info for Toukankahmoon

It possibly reveals the real reason Al had to go - he wouldn’t let go of AVA6000 to concentrate on a prodrug with better potential.

The king is dead. Long live the king.

You will find earlier in the year in my posts that I offered the possibility that all efforts were now focused towards the pipeline prodrug with the best potential. There is obviously some issue with monetising AVA6000 that we are not being told about. Hence slow progress and poor communications until Avacta has a new star prodrug to tell us about.

This is brilliant news but I now expect AVA6000 to slowly drift into the background while they sort out the issues. Meanwhile long live AVA6103.

GLA

DG

Thanks. I’ve had my rant. I’ll go back to gardening and wait patiently for the Avacta RNS😄

Vertizea

Thanks

BTW I also agree with Timmy. A view I have held for a while now. Hence my original (deleted) response. Just because you don’t agree, don’t delete the post.

CaptS

Head and shoulders?

I hope you are right

Great find

Massive RNS tomorrow. CC loves a Thursday RNS

Alderbaran

Who would have predicted . . . . .

Anyone who read the mouse data that’s who.

Ice

Development timelines that slip do not inspire confidence. You can ramp all you like but far cleverer people than you who probably have a better view of the data value this at 72p and there is no getting away from that.

Ice

The whole point is it has slipped. Just producing a new longer timeline doesn’t alter the fact. When inevitably a new timeline is published you will claim that it has reset everything and there is no slippage. Clearly you have never worked in a project environment.

Anyone remember this :;:::

“The excellent safety profile of AVA6000 should allow more frequent and/or higher dosing compared with the standard doxorubicin regimen which could in turn improve the outcome for patients. Therefore, in parallel with the completion of cohort 7, the Company intends to begin a short study to explore more frequent dosing (fortnightly) of AVA6000 as a first line treatment in patients with soft tissue sarcoma. The study is expected to begin in Q4 2023 subject to receipt of approval of a protocol amendment from the US Food & Drug Administration (FDA).

The study is designed to determine whether fortnightly or three weekly dosing should be the recommended Phase 2 dosing regimen, as well as potentially providing additional indications of activity in soft tissue sarcoma patients. The study will replace the much longer planned Phase 1b efficacy study, and is expected to allow the Company to bring forward the start of the potentially pivotal Phase 2 efficacy study into 2024.”

It’s called slippage. And when new timelines are announced it will still be slippage.

NFT

In my case I’ll be delighted (and richer) when this comes good. But that point is slipping further away into 2026 despite your blind faith in CC.

Lovable

Expansion was supposed to finish this year not just start.

You folks are just adopting the same head in sand unquestioning faith you had when Al was in charge. Meanwhile there’s been a whole world of missed investment opportunities out there where you could have doubled your money at least.

I’m probably wrong but I thought there was a time limit on ex employees taking up their options????

Cj62

Yes I know I do NYT Wordle🤣

Takes me back, but high schools in US cities can be very multiracial so more lenient and anyway Americans love Brits and especially the accent.

Also I am well aware of the US holidays. You have to be. Most folks base their annual 2 weeks holiday allowance around one or more of them. They think we are crazy to get 5 weeks and soon to only have to do a 4 day week. No wonder UK is in such a mess.

Vert

Sic does not mean misspelling.

Please don’t join the gang that love to find fault and attack people.

I lived and worked in Baltimore and both my kids went to high school there. In English my son’s work was accepted if spelled the English way or US way. Although I must say his English teacher really liked him.

So please don’t feel you have to personally attack me at every opportunity like the rest of the rampers. It is ruining this BB.

CC loves a 2H24 RNS 🤣🤣🤣

Bella

I thought CC was away until after Labor(sic) Day which is this coming Monday.

Hot off the press news from Bline59. Pray tell us more. Where did you get this information? When did it happen?