Member Info for tomvisual

Can we move on from politics ....
Test, test, test

Guardian reporting England’s poorest areas hit by Covid ‘perfect storm’ – leaked report
A “perfect storm” of low wages, cramped housing and failures of the £22bn test-and-trace scheme has led to “stubbornly high” coronavirus rates in England’s most deprived communities, an unpublished government report has found.

A classified analysis by the Joint Biosecurity Centre (JBC), produced last month, concluded that “unmet financial needs” meant people in poorer areas were less likely to be able to self-isolate because they could not afford to lose income.
https://www.theguardian.com/world/2021/feb/17/englands-poorest-areas-hit-by-covid-perfect-storm-leaked-report

Test,test,test

Guardian reporting Covid infections in England fall by two-thirds but spreading fastest among young
https://www.theguardian.com/world/2021/feb/18/covid-infections-in-england-fall-by-two-thirds-but-spreading-fastest-among-young

Test, test, test

On news bulletin, schools will test once.
Then testing at home. Frequency? Time period?

Test, test, test

Excellent question
Jon your on a plane who would you be more comfortable sitting next to ?
A... Someone who was vaccinated 3 months ago
B... Someone who was LFT tested one hour ago with a negative result

"We are not safe until everyone is safe!"
What's the no brainer answer???

Test, test, test

830x is fairly ramptastic!
£1000 investment turned to £830k! Transformational!!!
We all live and hope!
LTH for me!!

Test, test, test

If Innova, then is BJ just using up stockpile supplies?
Admittedly, would catch the most infectious pupils at that time.
But tests need to be on a more regular basis.
Article implies testing once at the start of Term.
Universities need better test rigour!
Perhaps this is just the start. Once into the psyche that its a simple test to do then it becomes easier to ask other parts of the population. Especially those not keen on taking up the vaccine!
Crawling before walking before running?

Test, test, test

Test, test, test

Looking at the Excalibur test, I note the following:
As noted previously, Excalibur is Nasopharyngeal. Prof Sir Chris Evans' media blitz paid off - and /or he has friends in high places to have got this through.
Prof Sir Chris knowingly makes this incorrect claim, "This test can be used with complete confidence in a wide range of everyday settings and will help organisations and businesses operate with the knowledge that their personnel are not infectious at the time of testing."
Sounds dodgy to me!!
No, no, no, no - and this is one more 'no' than Mrs Thatcher in her Bruges speech: if Sensitivity is 96%, 100% confidence can't be claimed.

The other, possibly, dodgy thing about the Excalibur test, amongst many, probably, is:
How is it possible to achieve 96% Sensitivity with a Nasopharyngeal test?
Thoughts:
* 96% Sensitivity with Nasopharyngeal tests, even with PCR processing, seems extraordinary.
* The Korean hospital must be exceptionally - improbably (?) - good at taking Nasopharyngeal tests.
* More details, in the form of a peer reviewed paper, are needed.
* I thought the UK government was saying they won't now accept Nasopharyngeal tests? Although, SureScreen and Excalibur both appear to be Nasopharyngeal tests, as is the Innova test!!

Test, Test, Test

SAGE came out with Ct of 25 as a practical value for LFTs. From the webinar link posted earlier, Prof Deeks is unimpressed with this.
SAGE's reporting process is far too opaque. It would be good to see SAGE peer reviewed.

For me Prof Deeks gives Avacta a qualified nod of approval, providing they behave themselves with the peer reviews.
Crikey.

Test, test, test

Listen to Q&A about 63/4 minutes in at
https://m.youtube.com/watch?v=L9Bq4sOnfQE&feature=youtu.be

Q2. 66 minutes in
Innova LFT was chosen because it was the FIRST company that provided LFT for DHSC to look at !!
That's what Prof Peto claimed!!
OMG!!!
Sir Al where were we!!

Test, test, test

Listen to Q&A about 63/4 minutes in at
https://m.youtube.com/watch?v=L9Bq4sOnfQE&feature=youtu.be

An accurate LFT allows for more testing on a daily basis! That's why we need massive manufacturing!
Hopefully, my assumption is correct!!

Test, test, test

Listen to Professor Peto after Prof Deeks presentation.
Peto also questions efficacy of PCR!!!
https://m.youtube.com/watch?t=2610&v=L9Bq4sOnfQE&feature=youtu.be

53 minutes in.
Full webinar at
https://m.youtube.com/watch?v=L9Bq4sOnfQE&feature=youtu.be

Seems to me S-gene and N-gene LFT may be the way to go as Sir Al suggested!

Test, Test, Test

Has Sir Al sidestepped Bojo and put the focus on Europe?

Test, test, test

Daily Mail reporting on Ready, test, go!
New Government slogan unveiled as PM plans to send testing kits to millions of homes and businesses with the hope of ending lockdown when cases are forced below 1,000-a-day

https://www.dailymail.co.uk/news/article-9268077/Ready-test-New-Government-slogan-unveiled-PM-plans-send-testing-kits-millions.html

Test, test, test

The, 'Heterogeneity of Innova LFT real-world accuracy' slide gives the detail about viral load and the Sensitivity for the Innova test: 'rubbish' may well not be a harsh description, certainly in comparison with what should be available shortly from Avacta!!
Shame the UK bought so many Nasopharyngeal tests from Innova.

Came across this pdf
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/943187/S0925_Innova_Lateral_Flow_SARS-CoV-2_Antigen_test_accuracy.pdf

Looks like with Ct 20-25 the Innova test gave 69% sensitivity!!
No comparison with the Avacta lft!
Viva Affimers!

Test, test, test

Did everyone open up the pdf in the rns??

Did you open pdf in rns??
https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/950695/s0958-liverpool-covid-smart-evaluation.pdf

WoW look at the innova lft performance!
Slide: Assumption that Ct<25 picks up most infectious:
Innova in Liverpool testing only picked up 40% of cases with Ct from 21-28 (PD)!

Test, test, test

How long did it take for Avacta to produce the affimer test assay for the Cytiva Lft?
3-4 weeks?
What timeframe is envisaged for the affirmer development for a Avacta/Mologic lft?
Similar?

Test, test, test

Correct!

Test, test, test

Exquisite!

Well done LTH!

Test, test, test

Lets hope we get S&S by end of Feb 2020!
Seems to me that I have been waiting over 6 months for this data!!!

Test, test, test