Member Info for tomvisual

Brilliant work from Carl and the team!!
The speed was always in the test.
Lets hope sub 1000 virons translates to MHRA Guidelines Desired Criterion!

MHRA Guidelines
Acceptable Sens > 80%, Spec > 95%
Desired        Sens > 97%, Spec > 99%

In Carl we Trust!
Carl's test - fast (tick), sensitive (tick), specific (tick)
Test, test, test

Doze, no doubt the statistics will be analysed to determine with the Avacta LFT whether that additional PCR test is necessary!
Hopefully, the accuracy of the Avacta LFT negates this. The Avacta S&N type LFT definitely should!! Or at least that is the intention.
Don't forget Sir Al is on record (from past presentations) as stating generation of affirmers is "a few weeks" !!

Test, test, test

For me, LFTs were never meant to be a replacement for PCR. Now with S&S levels at 96.7% and 100% and possibly higher with a S and N protein LFT, LFTs will now challenge PCR.
This is a fantastic achievement by Avacta.

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Guardian reporting
Concerns grow as UK Covid testing labs scaled back before even opening
Planned multi-million Lighthouse facilities cut by up to 50%, with smaller labs decommissioned

https://www.theguardian.com/world/2021/feb/27/concerns-grow-as-uk-covid-testing-labs-scaled-back-before-even-opening

Is the focus subtle shifting from PCR to LFT technology??

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EGTP, check out https://covid.joinzoe.com/data
for your answer. Scroll down page for UK map.
Despite lockdown and vaccines the cases per 100k is stubbornly high in most areas. First lockdown was at 98 cases per 100k in Bolton. So we still have a long, long way to go.
Do we know if vaccines stop the viral load of those that vaccinated with covid19?
Mass testing to identify local hotspots is needed to encourage isolation of infectious individuals.
LFT allows this tp happen at home, so individuals dont risk spreading the disease. LFT access needs to be like online shopping. Delivered to the door.

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Is the SureScreen assay from China?
Any CE Certification info?

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CE CERTIFICATION should identify manufacturer.
Needs to be in box

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Does an increase in Ct value of 3 result in a decrease in Viral Particles / ml by a factor of 10?

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From last years presentations affirmers can be produced rapidly, "in a matter of weeks"
https://avacta.com/how-a-lateral-flow-rapid-test-works/

I recall 4 weeks was the timeframe for Cytiva.
Could the Spike protein and Neucloidcapsid (S and N protein) LFT be readied for end of March???
Or is this a consideration for a later date?
The drive is to get a Product to market.
Excellent!

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Frequent testing, at least once every few days and ideally daily, is important so that as soon as the viral load of an infected person becomes high enough to be infectious that person is identified.

Highlights UK is not using LFTs as intended.
Presently being used as a rapid equivalent test to PCR.

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50pg/ml detection of S1 spoke protein.
First time in Rns.
6 times better than 300pg/ml previously mentioned (in presentations from 2020) that must IMHO have equated to Ct=25!
This IMHO equates to the fact that there is more bunce in the tank fir our test compared with other antigen LFTs!!

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Travel-light, see my post earlier.
Deepverge may use something similar woth our exquisite affimers!

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LiveDataAccounr, No problem.
SimplyWallStreet offer a free service of shareholder listing (for 1 week trial)

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Theres a TG?
Url?

Livedataaccount, Have you a Bloomberg screen??

The use of Camelid antibodies in the French test seems strikingly similar to the use of Affimers to bind to spike proteins, except that Affimers may be somewhat easier to fine tune to new variants.

I am trying to remember whether DVRG uses a change in optical properties or a change in electrical properties when the Affimers latch onto spike proteins. Can someone help me here?

Lots of claims, but what, actually, are the S & S?

Looks like a clever test idea, but, for poorer parts of the world, or home testing, is the use of electronics the best way forward?

Some points, looking at Google Translate's translation from the eurosante article, which is linked to in the Guardian article:
* The test uses 'Nasopharyngeal biological samples from patients'.
* 'percentage of positive agreement (PPA) of 88% and a percentage 88% negative agreement (NPA) on clinical samples, compared to a conventional RT-PCR test.'

Hmm, neither of the previous two points sound too good to me.

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Government Test Strategy outlined at
https://mobile.twitter.com/OffRecord2020/status/1364218616519024643

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Innova are no doubt marketing there tests on numbers of available tests each day.
That's when ultimate sensitivity is not an issue!
Mass testing is the ultimate goal here!
Which is Better:
- A 100% sensitive PCR test
- An 80% sensitive Rapid Test
Speed and frequency I recall from Mina.
But frequency is not once a week, its about having access to daily tests for 10 days.
Listen to Prof Peto, 1:04:40 in
https://m.youtube.com/watch?v=L9Bq4sOnfQE&feature=youtu.be

Rapid test and isolation was always the goal but no one has achieved it. We need to get on with a product to market to compete with the Innova product and other tests from China that are being or will be mass produced at very low costs!
Simple.
The time for action is now. I think Sir Al has the message!!
Test, test, test

The picture just got bigger and clearer for me!!!
Perhaps the drive by Sir Al is to get a product on the market?
Innova ain't hanging around.
Research tells me they are intent on upping their game from 8M tests per day to something much higher!
We need to get on with the best test in the world and start to get sales!
However, one thing I can easily predict, we do need a bigger boat!!
This can only come with licensing deals!
We need to motor and fet the show on the road.
End of Q1 is the deadline.
Are you with me are you without me.
That's the clarion call I want to hear NOW!!

Test, test, test

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MrMarkyMark, can you advise (if possible) if time duration from vaccination to positive test was > 3 weeks and what the vaccination type was used for your friend?

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