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Two key words, Bunsen...

"Posdibly'

and

"Spike"

It may not happen and if it does it will fall flat on its face in the vacuum of news.

It may also be "possibly" that there are delays and there's another fundraiser. Then that the safety limits are not reached.

Pays her money...

Far from it for me to suggest that unbridled ramping has being going on here over the last few weeks (Bunsen 😁),

But just for those newbies out there who seem to take everything in like a newborn baby...

The talk of £££s here is pretty disingenuous.

And also a word of caution on the FDA orphan drug... If you look at the statistics on this the FDA come back many times with further questions.

Not always, but if you're resting your investment on that it is a gamble.

I'm in at 9.7p , so don't.giveva monkeys but there are some naive new investors on here. Don't like to see people getting burnt.

Having said that for balance, this really should spike when the first patients are dosed. How high? No idea £30mill MC ? Possibly

I don't think anyone could accuse Cizzle of rushing the process, countingcards!

By the way, I'm guessing that the departure of our rather elusive CEO was somewhat down to chief shareholder, Edward Wardle, who probably demanded a position of governance and guidance of the company because of the large shareholding.

If past behaviour is a predictor of future events, Vinc, it won't be June, will it

Bermondsey...

Just on this specific point, yes, it's not like the launch of a new video game or something!

However, there are ways and means of approaching it with UK PR that would have maximum impact for a share price increase - that's if the company even want that, which I'm not sure about (depending on their private aspirations)

So, in the real world of impact marketing, the launch obviously should come with some fanfare..

Eg

"LAUNCH OF WORLD-FIRST STAGE 1 LUNG CANCER TEST ACROSS USA"

However, in true snoozy Syms' useless PR world it's looking increasingly likely that we're going to get something like:

"FIRST US PATIENTS TESTED WITH blah blah"

I've always maintained and still of the opinion that this will be very slow and not gain traction for the share price.

The first few patients to be tested will probably be in the dozens, hundreds, or few 1000s if really optimistic.

Still think they will be a blip upwards in the share price to circa 3 -4p ish then nothing to hold it up it up...

Unless.... They follow this up with some good news about the NHS and European roll out which could see it maintain momentum.

But I think most will probably be jaded and sceptical about the capability of the board to know how to utilise good PR.

Thalia means to flourish, bloom or blossom (in Greek)

Let's hope so.

Excellent news!

Old Nige has taken it as far as he can, but he's just out of his depth. He tried the Viagra reformulation which didn't work, and basically he's stumbled across NUVEC.

He's done ok getting it this far, but unfortunately the bloke is out of his League and a Billshutter.

Still no word of nanogenics (which has been laid to rest now in my opinion), but that just exemplified the folly of some of Nigel's decisions, and his disdain for shareholders.

Hopefully this will get really exciting now and get some traction upwards now it's got a new direction with a proper leader and team in place.

Ps...

And this may purely be semantics but did you notice Allan Syms' wording of when the test is first commercial in the USA.?

"Following CLIA accreditation, BIO will report when first commercial sales have occurred."

If that's how they intend to launch it, prepare for the damp squib of all damp squibs! Jeez!

Omni-health (a company patently lacking expertise in this area, with limited reach presently) struggling to validate. How do I know? Self explaining really. They’ve been at it months with the ‘help’ of our team, when validating shouldn’t take this long. Also the recent Linkedin post about how they’ve only just achieved ability to produce tests. Hmmm.

Allan Syms untruthful again about time frames, re: coming to market 2025.

(A video has him saying “very near term” in 2023, then RNS stating April 2025, then end year 2025, now Q2 2026…right, Alan! What a Billshuttter he is.

IgenomeX - zero explanation.

Alan - if you don’t know the time frame, don’t make it up; haven’t you learned yet? (I don;t think yoiu care actually).

You have the veracity and dynamics of S’Keir Starmer. Obviously a bloke who drives at 30mph in a 50mph zone and can’t change gear.

Ciz Bio US obviously struggling with funds to pay Ciz UK in timely manner (oh, this is Oh so predictable people!) Fundraise coming in April imo (probs between £250K and £500K imo - Green, ‘assuming’ again! About Langs. Maybe, but Assume - makes an ass of you and me.

So Q2 now? April to end June, IF you believe them.

Another RNS that informed about absolutely NOTHING. Obvious pressure from shareholders pushed them to a non-event RNS.

Took a few K off the table today to de-risk. Still got half in. Might buy more if fundraise comes in at circa 1p to 1.2p. I think price will slip anyway, but I could be wrong.

Good luck all, in the ‘never never’ company.

Ps and all that guff about extended funding to 2031!

The test and company will probably be obsolete by then folks. What a load of rot!

Unsurprising she leaving...

Wonder what she's been doing for the last couple of years? Making the tea?..

She must have been bored out of her mind!

"TM has previously been very good at neutrality"...

I'm sorry to burst your bubble lovelyboy, because like green you are a great poster...

But TM is a company man pure and simple.

Let me ask you, how do you gauge neutrality?

Good to hear from you Neil, and I'm sincerely sorry about your wife (and daughter) . At the time I read about a catastrophic Christmas accident on a motorway slip road near York.

If it was that one, it sounded truly horrific and my heartfelt sympathies go to you. But regardless of how it happened I'm sorry that you're in this situation with your family x

Regarding your post, I think you've summed up everything there. So thanks. Can't really add to that.

Thinshins...thanks . interesting.

Or several other options including someone in the know has got a sniff of bad news.or MM games or...

A multitude of other variables and possibilities.

I've had a bad feeling about Omni health since I first read about it...

Since they did not presently have any other offices open across the US. Bad smell to me...but

There's no way of knowing.. unless you're on the inside track.

The only thing I do know for sure is that when Allan Syms opens his mouth in those god-awful ass-licking "interviews" with the bloke with the worst voice in the world, I don't take anything that comes out of his mouth with any weight at all.

He's full of it, and time and time again has proved this.

I've come to the conclusion a while ago, Green, that you're one of these people who sees the good in everyone! Or you are prone to to severe confirmation bias, or you just do not see reality in the same way that I do.

You say that AS is not one for hyperbole?!?

If you mean hyperbole as stretching the truth and over exaggerating - of course is prone to hyperbole!

I would call it outright Billshut.

In 2023 he said in the very near term, they misled totally about IGenomex. You still are giving them the benefit of the doubt despite being incorrect with many guesses at when it would be launched.

For some reason you're still going down the non- evidentiary based assumption that everything is right and it's just taking longer than thought.

There is no evidence to the contrary either - but since validation is only meant to take a few weeks, and the company outrightly lies about time frames I've no idea why you continue to keep the faith.

I guess you're good natured. 😁 But incorrect more times than you're correct.

It seems that you base the assumption that they aren't having problems validating because Ciz Bio I've already dumped loads of money into this... But that is a circular argument, in that there was no guarantees that it would work at scale.

The first company obviously had problems. Now we are 3 months late for what should be validation.

Maybe problems may not be problems. If there are problems I'm guessing they are big ones. Omni health do not look exactly like a gold-star operation, but that's only an opinion based on skant internet searches. Also think there will be a fundraise in April.

We'll see soon I think. . I'm guessing the next RNS will be another "update on USA"... Which always means delays.

Hope not, but that's my prediction.

Ciz... The company that just keeps on giving!

Old UT trade trick.

Tomorrow it will show that it's up 10%

You asked what is going on here, Markoiler...

It's a very pertinent question.

My suspicion is they're struggling validating the test commercially or that Omni's apparent "expansion" isn't up to it.

Of course we could all be pleasantly surprised with a positive RNS , but the dire comms and eternal untruths from Ciz don't bode well. Imo.

For what It's worth..

On Wednesday lunchtime I had a 15-minute telephone call with N4P comms rep.

Although not much was said there were a couple of interesting things to be gleaned from it.

Firstly, the PR rep does talk to Nigel quite frequently so there is a conduit to what's going on if anyone wants to call the number.

Secondly, and more importantly, it was confirmed that Nigel definitely submitted the orphan drug FDA application mid 2024 (otherwise it would have been outrageous to be honest)

And it was also confirmed under some pressure that Nigel has been in correspondence with the FDA over this since.

Now since any formal FDA update would be price sensitive - let's say they required more information etc - Nigel is under a legal requirement to update the market on any developments.

Even though I think he's just brushed this under the carpet, I'm not going to let it drop because it reflects his complete disrespect of shareholders.

Over to you, Nigel, before some bad publicity arrives...

Ok, thanks everyone for the informative replies