RE: Minimum conversion price27 Apr 2021 19:49
Use of proceeds
The Facility will allow the Company to bring even greater focus to bear on scientific and commercial advances. The funds will enhance Hemogenyx Pharmaceuticals' control over its intellectual property assets under development and give it greater choice in determining what strategic partnerships to pursue and on what terms, enabling it to achieve maximum shareholder value.
Hemogenyx Pharmaceuticals has been successfully progressing in its development of its CDX antibody candidate ("CDX") and its HEMO-CAR-T product candidate. In addition, the Company has carried out considerable preliminary work on the development of its cell therapy platform as a novel means to allow the programming of immune cells to target both viral infections, including COVID-19, and certain types of cancer.
The Company intends to use the net proceeds of the issue of the Convertible Loan Notes to accelerate the development and marketability of its product candidates as follows:
§ Achieve clinical proof of concept for the Company's CDX bi-specific antibody product candidate if and when needed, including:
§ completing Investigative New Drug ("IND")-enabling pre-clinical studies that are needed in order to file an IND application requesting authorisation from the Food and Drug Administration ("FDA") or other applicable regulatory body to initiate clinical trials and administer the Company's CDX bi-specific antibody to humans;
§ filing an IND; and
§ completing Phase I/IIa clinical studies aimed at achieving clinical proof of concept and advancing the CDX bi-specific antibody toward later stages of clinical trials including Phase II and Phase III.
§ Achieve clinical proof of concept for the HEMO-CAR-T, including:
§ completing IND-enabling pre-clinical studies in collaboration with the University of Pennsylvania ("Penn");
§ filing an IND; and
§ completing Phase I/IIa clinical studies aimed at achieving clinical proof of concept and advancing HEMO-CAR-T towards later stages of clinical trials including Phase II and Phase III.
§ Achieve pre-clinical and clinical proof of concept for the Company's cell therapy platform (referred to by the Company as "CBR"), including:
§ completing the development and validation of CBR as a novel platform that allows the programming of immune cells to target either viral infections or certain types of cancer;
§ completing IND-enabling pre-clinical studies of an undisclosed CBR-based product candidate;
§ filing an IND; and
§ completing Phase I/IIa clinical studies aimed at achieving clinical proof of concept and advancing the undisclosed CBR-based product candidate toward later stages of clinical trials including Phase II and Phase III.
§ General working capital purposes