Member Info for Sparkle1

Scinv... did you open the links, listen to the Video (prob not as several minutes long), as that is the gov funded web site on how to get approval and help - then click on Synairgen which will take you through to RM heavily supporting it.

Scinv... posted twice already this morning...

https://www.nihr.ac.uk/partners-and-industry/industry/how-to-conduct-commercial-covid-19-research-in-the-uk.htm

https://www.nihr.ac.uk/partners-and-industry/industry/how-to-conduct-commercial-covid-19-research-in-the-uk.htm

posted earlier explains why and which hospitals were in the (Chris Whitty and Vallance approved the funding) fast track trial...
There are a few hospitals in the UK that are already in a joined up research group for pulmonary diseases per se - sorry cant recall name of what the group is called but if you are a pulmonary doc, you would know).

Did discover something when i had to get up early this morning... the serous trolls appear at 5am and are not on this board after 9pm. That means they are probably 4 to 5 hours ahead of UK time - which means Russia, Mid East etc. I mean who else is up at 5am for goodness sakes and in bed by 9 ??? unless you work on the markets as a broker or maker then you might be up at 5 i guess if you have a long commute. But it aint normal is it!

Difficult to check Parsleys past history as i cant believe the majority on this board didnt filter him a long time ago and have no intention of unfiltering anytime soon.

Vallance Whitty and Fauci have the widespread support of the NHS and medical community. Lets not get rid of the good guys just because they are experts in their field, to replace them by muppets.

after they had recommended Cineworld LOL

It really didnt need a higher risk tolerance at £2 - thats the price the serious ii's started to buy in at.

When i sold my business, we had 3 other directors. One chucked everything into Amazon and Google just cos he liked them. I stuck some into Amazon and when it got to 398 in 2013, thought I'd made a killing, couldn't see it going higher and got out. Other director still in Amazon and £35m better off. I've been in Synairgen since Woodford bout in in 2015. Some things you just have to forget about and park. If you are happy to have made a grand or lost a couple of hundred, then leave. If you need the dosh, leave. If you don't then either sell early as i did on Amazon and try not to look back at what might have been or stay in and forget about it for a bit and see what else you can do. Otherwise sure way to go completely nuts, especially now when we are all going a bit nuts anyway.

and Synairgen founder is consultant to Novartis - guess he'd better resign as they make vaccines... what a load of hogswash there is on this board. People are dying out there. We all need as many treatments and vaccines as work - this isn;t a global monopoly for one thing for goodness sakes.

and Chris Whitty approved the gov fast track status for Synairgen : does that mean they are both rogues? Who is to know if they are not also invested in Synairgen given they approved the fast track gov pathway for it? Have yet to meet a doc who doesn't rate Whitty.

https://www.nihr.ac.uk/documents/case-studies/urgent-public-health-research-synairgen/25079

There is an awful lot of drivel on these boards, especially yesterday where people were suggesting it was **** easy to just go recruit any old person in home or wherever... so it might not be a bad reminder as to how the Gov and 10 of the top hospitals were engaged and recruited to do UK Covid trials and how Synairgen and Novartis take top spots on this...

https://www.nihr.ac.uk/partners-and-industry/industry/how-to-conduct-commercial-covid-19-research-in-the-uk.htm

This is the UK Gov backed process and looks pretty efficient to me. So the suggestions yesterday we can all recruit in Bradford or whatever can probably fly out of the window - as we need to be in the mainstream process set up by UK Public Health to do this stuff and we are. Suggest everyone open the link above and then half the drivel might disappear):

https://news.sky.com/story/coronavirus-people-co-infected-with-flu-and-covid-19-have-far-greater-risk-of-death-12078402

However, it is probably the reality that the trusts will want the medics to prove it is cost effective over what they have currently apparently already bought for a second wave:

https://www.marketwatch.com/story/uk-approves-use-of-life-saving-coronavirus-drug-dexamethasone-in-biggest-breakthrough-yet-2020-06-16
So the cost benefit within nhs, will probably be done on how many days one is in hospital + increased deaths/intubation. I dont know how many days less you are in if you take dexamethasone. Also, dont know if anyone can tell me: i think they do different things so i am presuming you would take both as one is a steroid and the other an anti-viral? Is this correct? Anyone know? The chinese are giving interferon in their trials alongside another drug (posted earlier).

Im wondering if the nebuliser comment on point 3.2 below is significant... maybe they are nervous about nebulisers in hospitals given that my regional hospital (and presuming this is true of others across UK), has not been doing endoscopies - they are all suspended at the moment for this reason. So i'm wondering if the hold up is that is might be critical to have the in-home results to take the risk out of the hospital setting. In any event, they should be able to finish recruiting the in-home trial shortly given the growth in cases every week. I also asked a couple of key guys at Charing Cross what they thought of the repot and the response was that they would never action one research report alone. Hence, the surfing and found numerous tests for interferon alpha and beta on other studies relating to coronaviruses, going back to 2003, which all seem pretty positive and in same vein, coming out of China. So maybe one issue is that not enough is being presented to those in the positions of power where they can see other historic medical trials are getting not dissimilar results.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7334905/

Interesting comment on nebulisers if you page down to point 3.2

https://www.medrxiv.org/content/10.1101/2020.04.06.20042580v1.full.pdf

Seems to back up Syn position - from Wuhan. I think it would be quite good if China started to treat people with Interferon as the west wont buy from them if there is an alternate and we have no patent for China?

https://www.aljazeera.com/indepth/features/doctor-note-wearing-glasses-protect-covid-19-200921051558545.html

Written by a doctor in our NHS - on Al Jazeera main web site. Just dropped him a line on Syn for his view given he seems to have access to Al J.

if a company making Interferon gamma is likely to also be able to make interferon beta?