RE: Found this31 Aug 2021 09:57
Quote from article. This is exactly what 4D are doing.
"If checkpoint inhibitors release the brakes on T cell responses, Marc Ballas, a medical oncologist, is investigating a treatment approach that steps on the gas. Ballas leads research and development at GSK on agonist antibodies, which could increase the response of T cells to supercharge attacks on a cancer. In Ballas’s view, inhibitors could be combined with an agonist to great effect. “We may be able to dial in and out the impact of each drug on the cancer,” he says. “That way, maybe we could modulate the immune system for just the right degree of response.”