Member Info for Safy

Sensitivity is in the white paper isn’t it? Abi’s own validation.

Tco,

Share buyers also have that in their article about it being 98%, however this isn’t the only validation that’s been done on the test. Abi have it in their white paper they tested to over 98%. So it’s slightly subjective. 0.4% out to make it over 98% from Ulster.

Where is a scientist when you need one.

Bigjock

The time they set themselves was approximately 6 weeks. They failed to complete in the window they gave. Hence they completed on swab.

There is nothing bad about admitting that. It’s in the RNS.

GDR worked together with a global giant in Beckman Coulter, BC are part of Danaher group. Look up Danaher SP.

It’s very very hard to crack saliva.

Merch

If Mologic crack the Elisa antigen ‘Saliva’ it’s MASSIVE. CK confirmed the aim is for Saliva NOT swab.

GDR failed to do It with Beckman Coulter jv, read the validation RNS. How many saliva covid tests exist in the UK in a live government setting? Zero to the best of my knowledge.

Spit in a cup and done. People underestimate the importance of Saliva testing.

Greg,

This is exactly what this test is designed to do according to Blair’s testing document.

Employers to give staff tests so they can be ‘relatively’ assured they will be safe on the job.

itsallagame,

give it a rest mate, they only just came out. You wanted to see us make a test, well we have, you wanted to see us sell them, YES WE ARE!!!, now you want orders already all in the space of a day?

This Qualitative rapid diagnostic test detects IgM, IgA and IgG antibodies. The manual lateral flow immunoassay is for professional use only and is not to be used for self-testing.

The cartridge contains 4 sections:

C – Control line
A – IgA
M – IgM
G – IgG
Any red line (A,G,M) or multiple red lines indicate the presence of Covid19 Antibodies.

Is this test better than RTC? it has a line for each Antibody....?

Super find!!

i think its about getting the first order through, and thereafter we can build on that.

I've been thinking a lot about this, and it seems that this is the wrong time to do mass antibody testing. Allow me to explain.

This is a moment of lockdown, not releasing restrictions. imagine giving a license to some to live normal lives right now....Once the government has a grip on daily cases, daily hospitalisations, daily deaths, they may well consider easing some restrictions and that's where antibody tests play an important part. Same way we have regional lockdowns, perhaps they would have regional releases...??

Come Feb / March 2021, possibly after wave 2, they'll need to do a lot of antibody testing to gauge what % of the population have antibodies.

Likewise, when the vaccine comes, they'll need to do a lot of testing then too about who is eligible and who isn't.

However for the consortium, this isn't kicking the can down the road, given that we can only make 200k tests a month in October, I think to produce a few million tests is definitely more than a few weeks work. The government dont like to mess around and hence dealing with small companies doesnt work well with them. Imagine signing an agreement only to be told they can have a few hundred thousand tests a week.

They want big numbers, and quite frankly we are not ready to give them big numbers....yet

I gave up after boots, anyone else see boots on abi’s follow list?

Can you pls share names of a few?

Some people are just plain stupid, I could use a lot more colourful language to describe these people but I’ll resist.

Anyone that doesn’t believe me go on twitter and search #ODX, there are idiots using news articles and tweeting they need to use antibody LFT tests to detect covid in nursing homes.

They honestly don’t know the difference between and antibody and antigen test. It’s those people who posts daily crying where the RNS is pretending they’ve got thousands invested.

@MB

Do you know specifications for our Saliva ELISA Antigen?

Access denied.

Can you summarise, good or bad?

I have emailed ODX for clarification. If it’s Saliva then that is significant news. Something that has been overlooked by the bb.

Upomega / unvrkw

Lol which one? Saliva or blood?

Mologic

Mologic currently has four serology tests available.

ELISA test for IgG only: This test is available now, and production could be scaled to 500,000 tests per week. As it stands, there is no sign of the test being validated by Public Health England (PHE), but there have been positive conversations with PHE Colindale.

Professional RDT for IgG, IgM and IgA: These diagnostic devices would identify a full range of antibodies. Forms have been submitted to the New Test Approvals Group (NTAG) but no reply has been received. The test is being provided on a not-for-profit basis with a number of international partners and there are proposals for 200 million-plus capacity units here and in Africa.

Self-test for IgG only: This home-testing kit could be used by a layperson to identify if they had IgG antibodies and therefore had some evidence of past infection. To date, the regulatory pathway has been blocked by MHRA.

Laminated test in IgG only or G, M and A: The laminate tests provide a quick result and show if a patient has had exposure to Covid-19. Plasma from a sample soaks along a laminate of what is essentially paper, encountering a zone that has known coronavirus antigens. If the plasma has antibodies to the coronavirus proteins, those will bind to the test antigens and carry them along up the strip giving a result. These tests are being developed for both professional use and self-testing. They are being distributed internationally.

What’s in the pipeline?

In the medium-term, Mologic is developing T-cell and Memory B-cell marker variants of the antibody test to confirm immune memory. These are critical to the debate around immunity.

The pre-mentioned antigen tests are subject to regulatory hold-up but could be online very quickly. The company is also looking to develop peptide antigen driven tests (for lower cross-reactivity), similar to that of the HIV rapid tests.

Antibody testing is potentially an important part of the puzzle. Further evidence is needed on the level of immunity conferred by infection, but we believe it does confer a level of protection from reinfection. In addition, we are increasingly seeing evidence of long-term health implications in patients who have had Covid-19. Without a broader understanding of who has had the virus, we will not be able to understand this issue more fully. Large-scale rapid antibody testing will help build up a picture of who has had the virus, providing important information.

Antibody testing to support PCR testing. Where employers are running larger scale antigen testing (eg, to avoid shutting down operations), some are also offering antibody testing so that they can avoid regular PCR testing for a three-month period.
Antibody testing provided as an employee benefit. Some employers, particularly in financial and legal services, are providing voluntary antibody tests to individuals to enable them to find out whether they have had coronavirus earlier in the year.
In recent months there has been increased interest in antigen testing. However, to date, we haven’t seen any evidence of mass antigen testing by employers to manage core business activities. This is primarily because only lab-based swab tests are currently available. The key game-changer in the way employers will use testing will be the commercial availability of simple self-sampling (nasal or oral swabs) and rapid turnaround of results using alternative test modalities to PCR.

Widespread availability of instant-result antibody tests (eg, the AbC lateral flow test) may also enable employers to monitor whole-workforce immunity status over time.

From the link....Isn’t that our test?