Member Info for ratcliffewriter

The the I was pondering was what would I favour if I was Redmile/Vulpes? I suppose a lot would depend on the size if any buyout offer - fun to ponder, but that data has to come in and be very good first!

Talking of data, they hoped for 70% orr to put it significantly ahead of the current standard - the fact (thus far anyway) it is very significantly higher has to be a massive bonus. While the sp hasn't done great things, I imagine those who are watching will have raised at least one eyebrow and continue to watch. Just being mildly optimistic, as I think we are allowed to be!

SA article which makes familiar but interesting reading, and a rumbling problem facing a number of significant revenue generating drugs. Now IF scib/iscib produce data of the quality hoped for (83% orr is not to be sniffed at) where does this leave scancell? Get bought out by the expiring drugmaker, or fend off any approaches (RM and vulpes own enough shares to do this) and then in couple of years become one of the new leaders using scib plus a generic combination drug?

Just food for thought.

https://seekingalpha.com/article/4653853-bristol-myers-squibb-the-patent-expiry-challenge

Any way up, Clatterbridge is getting good results, Clatterbridge is a major immunotherapy centre, Scancell have trials ongoing there, and the. SCIB1 trial is exceeding its target percentage by a considerable margin and kicking the current multi billion standard of care into the weeds. Small numbers, but growing numbers, and data from a very very realistic, down to earth and credible boss. I'm pretty relaxed thus far, basically.

Maybe 'Twerp, Whya.' Can't think why, but the initials look better in that order.

A sheriff has power and influence, the question is whether that is used for the benefit of the townspeople or for personal advancement of the sheriff and his hangers-on. That's why the Clint Eastwood westerns were such a hit.

Unfortunately the discount on the haircut is offset by the search fee levied on the more folically challenged.

To be honest, I've followed sclp for so long and watched their science evolve in an intriguingly good way over the years that a few administrative or PR gaps really don't bother me, and the chances of a massive rise or expensive buyout seem far more likely than a crash to bankruptcy or even a dire bumbling along from placing to placing, so I am quite happy to just sit by the sidelines and see what comes up. Imo it looks increasingly useful, but time will tell, as ever.

Baffling isn't it?

PI8 - If as you say 'I think we had a non-binding agreement, but that has recently changed into a contract' can you think of any reason why this would not have been immediately publicised via RNS, and would the company not also be required to release an RNS if this had actually happened?

A lot of very understandable frustration, and while I'd rather have information from the bod as well as scientific facts from trials etc, if I had to be in the dark regarding one or the other, I'd pick bod silence over absence of trial advancement any day. It's how it's always been here, so while frustrated I think most lth are pretty much reconciled to it.

Are you allowed to mention that Porky? We shall see.

Jockvest - high probability your post is removed within an hour or less.

Strange goings-on when a post is removed (on a Sunday evening too) saying that the unsubstantiated positives here almost makes them want P9's prediction to come true, yet a poster with an opposite standpoint suggesting that P9's wife might wish she had a cyanide pill is left in place. Something is rotten here, surely?

Never known dissenting posts removed so quickly- no effort to rebut or discuss at all! And all weekend too - that's quite exceptional even for LSE.

The same perfectly reasonable question for discussion on clinical updates on 201 301 and 401 keep getting removed, and suspiciously quickly too. Very disappointing, and makes you wonder what is really afoot. Remember the very strange meeting between Tom Winnifrith and Satu, after which TW promised notntonsay anything negative about Val? Is history repeating itself in some way? We shall see...

As an alternative consider this - if chatgpt had said 'Scancell is a bankrupt lifestyle company with no useful science and will be heading down the pan any day now', we'd have had at least fifty posts today from our resident and closet 'balanced' team telling us about the accuracy and precision of chatgpt. Bear that one in mind - you know it's true!

I ran the same question through LozGPT and NOW every few words it CHANGES to capitals at RANDOM, and it just kept blathering on about LAWN cutting, squirrels and firewood.

So basically the latest cutting edge artificial intelligence says 'DYOR.'

'highly impressive' and 'meaningful improvement' are good to read.

What party?