Member Info for Quickdraw18

J&J could do with some COVID Mice.

Good job they have a partnership with Hemogenyx and Hemo's Chairman invented J&J's best selling drug with $36b sales to date

"Johnson and Johnson (NYSE:JNJ) recently announced that its Janssen Pharmaceutical Cos. will collaborate with Emergent BioSolutions to support the manufacturing of its lead investigational COVID-19 vaccine candidate"

https://www.massdevice.com/how-johnson-johnson-is-expanding-manufacturing-for-a-potential-coronavirus-vaccine/

Can anyone recap how long D-PCR will take?

I belive 30 mins

Good RNS, pitty historic and future sales are mixed in. Tough to extrapolate and work out unit pricing. I assume that was their plan

Has a date and time been set?
Also does anyone know if their will be a conf call?

Sorry if been asked already. Am struggling making my way around all the BBs in good time

I second what JAdam said. Well done on your purchase

Company has received a massive jump start, after some time in the mechanics. Has a new, COVID chassis, with the same specific a bodies driving it forward with driving team of crash trest mice.

Hemo have many sports cars in development, COVID, AML leukemia, HIV and many autoimmunity conditions. Abolishing Chemotherapy will transform lives of many leukemia sufferes.

For investors looking to the long term I suggest you find out Dr Sanders article on the passing of his father to leukemia to understand his lifes goal. Its not riches or notoriety, its to save lives so others don't have to suffer as his father and faniky.

For me this has akways been 3+year play. I
intend maintain a large holding until commercialisation.

I would hope new investors can see beyond any near term COVID impact and look to the broader possibilities of being able to exact white blood cells from the patient to treat their own conditions.

In the world of global travel and diverse genetic makeup, using patients own white blood cells will play an ever growing role in treatment of Immunology conditions.

All else fails, maybe we can bread a generation of humanised mice who are prepared to carry the torch for humanity once we are gone lol

A quick, successful COVID program will accelerate Hemo through its broader development, increasing access to funding, resources and collaboration.

I go on about COVID time, belive there is serious value to this. Seem many companies rise to £200m caps in weeks/months.

Hemo is lucky to have Sir Feldmann and his experience in bring to market $36B product and the security of the founding owners Vlad and his wife owning 50% of business (from recall)

mornington-oz I would be cautious investing in Hemogenyx, they are very speculative stock. I've 3% of holding with them. Enough for me to retire for many lives should they unicorn. Im also prepared to write off 70% of my investment.

Hope some people ignored my recommendation NOT to buy my stock dog Hemogenyx. Is up 120% since.

You know your on a roll when your dogs start looking like unicorns :-)

Handyman10 are you from the OLED board?

Well done everyone who held. Mindless selling hottest stock in the world. And don't forget this was just an appetizer. Sales RNS to come on tue or wed.

Don't be short, think of your children!!!

Shunkan, you missed the part of RNS where Hemo specifically say they are looking to commercialise as test :

"Concurrently, Hemogenyx has initiated a pilot study to understand why some individuals who are infected with SARS-CoV-2 are asymptomatic, some exhibit mild symptoms and some become very sick. Such understanding could prove essential for both the development of new treatments for COVID-19 and managing the current risk of infection. Should the study prove to be successful, Hemogenyx will aim to develop and commercialize a test that could identify people with potentially high/low risk of severe illness caused by the virus"

Sneaky and Tiptree don't shoot the messenger. I didn't create the data. I shared my source of "CLOSED CASES" survival rates.

The UK and a few other countries don't provide the % or number of recovered patients. One week ago we had 133 recoveries and about 16k cases.

Closed cases outcome % is worked out as % of Recovered to Discharged.

Obviously amount of testing outside of hospital setting will reduce %, however i have not found any data to explain why the UK's rate is so, so much worse than any other country

Have others noticed and been alarmed by the UK closed cases?

UK hospitals would seem to be a 8 week death trap and no one in our media is asking questions!!!!! 96%+ fatality rate

https://www.worldometers.info/coronavirus/

I've suggested to a couple of Fools I'm in contact with, they weren't interested as not long plays. There loss, im is up 258% since i tipped then. Oh well lol

Agree the DM hard-line could be there fore dostraction. Is going to take a heck of a lot to distract from what i fear is to come.

Based on UK data from Worldometers it looks like UK is course for approx 120k deaths within 8 weeks. Worldometers have stopped recording UKs recovered cases and outcomes. Last time I checked entry to a UK hospital with COVID resulted in 96% chance of death.

This leaves me to belive that the majority of existing cases (130k) will sadly result in death.

Criminal this isn't being covered by press. The only other country I can find with a comparable rate is Sweden at 69%, Germany is at 6%

VanV as you have RP's ear it would be great if you could enquire why our case outcomes are so far below all other countries and why this data is not presented to public.

Case outcomes / hospital death rate
Germany - 5%
Spain - 16%
Italy 29% -
Iran - 8%
S Korea - 2.7%
China - 6%
Ireland - 10.5%

https://www.worldometers.info/coronavirus/

PS for the month im spouting a Hitler mustache as a not so subtle sign of the genocide occurring in our care homes. I won't be forgetting those who who sat on their hands for 2 months and willfully killed our old and in need. I hope large lessons are learnt by those gaslit to no long belive in society, hate on migrants and devalue many who are now trying to hold our country apart.

We need to all come together, rich and poor, we fall as one, be it this or climate change.

Rant over sorry, back to money and greed

When COVID and the COVID bubble is over

Hi Mkumar, it's likely the CEO Dr Sandler will respond to you. His email is vladislav.sandler@hemogenyx.com

One thing to note the cells are not harvested from mice. The mice were developed to test the antibodies which are currently sourced via donors or placenta, but in the future could be extracted from the patient themselves which would be a game changer.

The COVID Mice will have a humanised immune system, this will allow companies to infect mice and test treatments or inoculate with vaccine.

Not recommending anything lol. Please do your own research. 95% of bullet board posts are BS.

A little help for newbies, check companies annual and quarterly reports, conf calls, development announcements, patents etc. For UK listed companies you can check prior RNS's on London stock exchange.

https://www.londonstockexchange.com/exchange/prices-and-markets/stocks/exchange-insight/company-news.html?fourWayKey=GB00BYX3WZ24GBGBXSSQ3

For small cap companies it is important to check out management teams track record. Obviously many failures is a red flag. This is Bio the odd failure can be ok depending on circumstances.

Be mindful we are in a hyper bubble like never before. We have no idea how long this will last. Some companies will gain massively in the short term, some will continue to prosper. Many will be a flash in the pan (many USA made anybody tests i belive)

Don't get greedy on a stock, don't get attached to a stock its not your baby it is OK to sell it, depending on size of holding its sensible to spread you risk.

Also don't get sucked into the false lure of trading. Trading fees £24, if you are trading £1,000 you are loosing 2.4% each trade, more importantly there is a 11% spread on Hemogenyx. 13.5% just to break even.

Been served so well by finding great ideas and transformational companies and holding. What are our future needs and who can meet them.

Should I'm not recommended chembio or omega they are wild dog bets of mine. Ocado is probably pricey right now as well.

Thanks all for kind word folks :-) much appreciated.

Big up Dr Sandler and Sir Feldmann what they have achieved so far is pretty impressive, under a tiny budget.

Hemo raised £650k in 30/01, lilely to give head room to avoid getting squeezed during CDX conditioning negotiations with the unnamed global pharma as they have been dragging. The lower Hemogenyx's cash balance the better negotiating position for Pharma.

Hemo cash poor, if they are to enter COVID space they need money fast. Share price is too low to raise meaningful money. However they've had months to develop COVID mice, a mice deal will likely send shares up x3 min and validate AML in vivo tests. Can then raise money and sign development deal for their targeted antibodies.
If there is a need for their test this will also have to be outsourced. Hemogenyx's workforce is tinny, collaboration will be key.

For AML agreeing a deal has been a 2+ year process. In COVID time this needs and could happen within 2 months.

I suggest a big couple of months for Hemo and us ground floor investors. If they don't progress in COVID i have concerns for AML as trails for non COVID are mostly on ice. COVID success could turn Hemogenyx into something else

I'll be buying a mill+ shares soon, am waiting on Novacyt sales update before buying in.

Been on a great COVID run. Sold most stocks in feb and then bought:
Avacta 60%
Chembio Diagnostics 45%
Novacyt 280%
Omega Diagnostics 35%
And my first COVIF stock Ocado 39%

Held Hemo for 2 years, recently down 60% but as they have shown they have great pedigree. Up 13%. Investing half finding the right company and 50% patience and holding your nerve.
Good health all

Vanv, seems quiet on the OptiGene front. The Basingstoke crew are doing all the work. I expect like us they are waiting on PHE. All the signs are their for a Basingstoke, Optigene, PrimerDesign team up....

https://www.linkedin.com/posts/activity-6658365563355697152-O3x-

I have been invested for 2 years at 2.06. The stock had been on the decline for a year while company negotiates a deal with a global bio for one of its leukaemia treatments. Has taken off as their technologies have broad application.

They have deals with J&J, Oxford University, rockefeller university, cornell University (where CEO discovered Hu-PHEC cells), plus a development agreement with a global pharmaceutical company, which is in the final manufacture ability stage.

The pivot to COVID is not out of the box. The company have been aiming to use their humanised mice in the bio defence industry for a year.
Normal lab mice are not suitable for COVID testing as thier immune systems are too different.

Hemos mice can enable companies to rapidly trail covid vaccine's and treatments quicker, cheaper and lower risk.

Hemogenyx mice were developed to test their leukaemia treatments. They have a small amount of supply deals for their mice. Should they be a able to secure meaningful mice deals this will validate their internal vivo leukaemia treatments.

All said the mice are a means to an end. Their primary focus is the treatment of immunity conditions. Currently Leukaemia (AML)

Back story
Cornell University CEO Dr Sandler discovered way to extract white blood cells from adult patients. These blood cells are grown and transfused back into patient. Therfore removing need for blood donors and the issues with finding a match and body rejecting the blood. This treatment is probably 5 years away. The applications are many such as HIV and now maybe COVID

Their second candidate treatment, being developed first, for which they have a development deal and are in discussion with global bio company over deal is a CDX bi-specific antibody. The treatment conditions patients blood prior to bone marrow transplant. The Conditioning is currently done via chemo which 60% of leukaemia suffers can not under go chemo with deviating results. The antibody has recently been shown to also treat leukemia.
In recent times the company has discovered treatment with the CDX bi-specific antibodies can lower the toxicity of some failed treatments by 100/x200 (please check RNS's for details). This could reopen the door to many failed medical treatments.

Now on to COVID. As discussed the mice could speed up drug trails and enable a broader range of trails. To note I belive mice take 12 weeks to grow before testing maturity. Dr Sandler has been in the know since mid Jan judging from Twitter.

Their last RNS also spoke of how their bispecific antibodies could also be used to target COVID and how they had developed a mild/sever COVID test.

I suggest the COVID test and treatment need funding and global pharma. I had a 3 >4yr £3b valuation prior to COVID

From my geneticist friend (staff lol) :

"Coronavirus isnt that mutagenic. Not as high rate as flu viruses. The number of changes are low and would be unlikely to affect primer and probe annealing. Pce can cope with some differencea...but also massive sequencing efforts at gsaid...soi think theyve got it covered

I am not in the least worried about test stopping working. Especially as theyre monitoring changes. They will be targeting essential part of sequence too which will not tolerate large changes"