Ben Richardson, CEO at SulNOx, confident they can cost-effectively decarbonise commercial shipping. Watch the video here.
Isn't she just.
Casirivimab plus imdevimab - otherwise known as monoclonal antibodies, expensive to produce. Limited evidence and probably not effective against other strains. Doubt these are $100 or less per treatment. Trumps course was $300K and US is dispensing 1/4 doses at 80K.
neutralizing antibodies - yes because that looks to be working. I don't have costs/benefit to hand.
remdesivir, Discredited as no actually benefit over standard care, already answered.
dexamethasone - Late stage. Reduces death to 1 in 3 along with other existing care.
Oxygen - you excluded this in your original message.
Vaccine - not defined as a treatment. I won't get into the whole vaccine vs treatments here - its been done to death.
mask, social distancing - not treatments.
You missed tocilizumab and sarilumab.... added this week and late stage. Reduces death to 1 in 4 along with other existing care and dexi.
Anything else or is that it?
"A $3k treatment is not a first line treatment when there are at least 3 medicines already that give effective treatment at less than $100 per dose, excluding oxygen therapy."
Genuine question - what are these effective treatments?
Only no one has told the NHS, FDA, etc, as they have record numbers?
mAbs has been approved for hospital cases in US but costs a lots than $100 per dose. Remdesivir has been discredited and costs more than $100 per dose.
All treatments approved in the UK (there are 3) are later stage, i.e. when the patient is already in deep **** and reduces death to 1 in 4.
The added therapies - the 24% is relative to existing care. Cuts odds from ~37% to ~25% so 12% reduction on overall odds of dying. now 1 in 4 instead of 1 in 3. Still better to not be there in the 1st place.
Synterferon - okay who bought the .com domain???
Currently $990......
As discussed before on here they cannot Market an unlicensed medicine.
If a doctor knows (or a patient is maybe aware) it can be requested via MAP.
RM basically stated this is a mostly set up as a distribution channel, should it be needed for any EUA.
Its also incorrect - so I wouldn't post this as a response.
SNG are now doing a P3 there was a whole RNS, fundraise and RNS including FDA authorisation (only this week) on it.
Maybe its worth directing the MSP and others to this current information rather than the MSP's incorrect response.
The P3 Trial is known as SNG018.
Its a message - basically the home trial is further along than the academics are aware. The numbers they gave are not current/correct.
I'm keen to know if any hospitals in South Wales are included on the trial...
Just in case... Lol
I'm not sure that's true (hasten the EUA) as the P3 and Home trial are aimed at different stages of disease. Also, only 100K+ treatments available per month initially so will want to target at the most need (hospitalised) which is P3 results (interim or full). Adds support and will be good news though.
Obviously, desperate times and change of government in US, so all options are on the table. We wait to see what RM has been cooking up with FDA so who knows!
I'm not so sure - they have been happy to let the corpses build up so far.
Remember the whole purpose of lockdowns/Tiers is to prevent the NHS being overrun.
However with US and UK hospitals overrun you may have a point. Once the hospitals reach capacity the death rates increases and that will look even worst than now.
£100K - Its all relative to individual circumstances....
Its certainly a nice cushion and can be life changing but it's not life changing in the wider scheme of things.
As pointed out, its not an amount that you can live off the interest or a 5% investment return, its not an amount that allows for a regular income on its own over a number of years (I guess 4 years is possible as an individual depending upon Rent/Mortgage costs).
For some living on £200 or less per week - its an enormous amount but it won't last long because that person is probably up to their neck in debt or really struggling. In the same token are these people that are putting amounts into AIM holding and hoping to hit the 100K+ score.
Obviously my figures ae subject to review, and assume that our assumptions hold. If we get to Q3 next year and we have mutations and figures at 25%-50% of where we are today with a successful treatment - all bets are off. (Potential valuations are massive.) IMO.
£5 Might get my SSA shares but really that price is more like £10.
That represents about 5% of my shares. The others are probably available at £20+ - depends on the outlook at the time.
Thanks for replying EVA,
I understood all that - most of my investment is also in ISA/SIPP. I didn't appreciate the difference between multiple buying/selling on a share being CGT or Trading (outside ISA/SIPP) - so I was clarifying if Trading inside of ISA/SIPP was differentiated the same way outside the Tax wrappers.
Also, glad the topic was raised as I could have quite easily have 'Traded' in my Stock & Share Account - had I seen opportunity to do so.
Planning on Visiting Malta some day (was scheduled for Nov but cancelled) - so can you recommend a good coffee house.... :-)
Hi Sparkle,
This doesn't apply to SIPP or ISA though? Can you effectively trade (not that I do) within the SIPP/ISA as often as you want?
Thanks PJ
Doc - 40%+ of US won't take vaccines. They are not getting away from COVID anytime soon. That's 150million plus people and they are only about 7.5m of the way through. 1% is 1.5m people (we're potentially looking at 5%). That is one market (albeit probably the largest and most profitable). Its Pandora's box and its been opened.
These are people who don't believe in Masks, Covid, Social Distancing, etc.
Okay I'll play this once.
1. Status on Trials register has been set as on-going for some time (at least 1 month).
2. RM (the CEO) stated on the 18th November the P3 hasn't started, thinks will start 2-3 weeks. TW describer the start date on Monday as imminent.
3. SNG released notification of Trial Start and dosing for P2. No reason to think they wouldn't do it for Phase 3.
4. Phase 3 start is likely to be price sensitive in the current context.
Its not underway until you get a RNS that says its underway.
I may accept the word 'recruiting' as maybe its actually started however this probably follows on from said RNS.
The Trial won't be terminated it will run to full collection - there is a very important outcome of this this trial that is being assessed. LONG COVID.
The data points at 60-90 days - scientifically I suspect they provided more than just the effect on Covid (broad anti-viral effect of inhaled interferon beta).