RE: Science Day27 Nov 2022 11:02
The committee advise and they’re extremely likely to follow the advice. Yes, I think they *should* give an full explanation if they go beyond 4 as it’s a change in previous advice. I’m not convinced they *will*. I’d be delighted if they did, but I’m also setting my expectations according to how awful they’ve been in the past. Their explanation could be as succinct as them saying, again, that they’re delighted with the excellent progress. They don’t need to release any data at this stage. They’ve already said they might not find a MTD. I completely agree with you BITL, but I’m more than prepared to join the disappointed ranks. Who knows, they might move to 1b and keep 1a going - I hope so.