Member Info for NFTs

It is as they hold 40 years of proven safety data on the drug and the whole point of using an approved coformer with the drug means it hasn’t changed in regulatory standards. The time dates would be significantly faster. Those dates are there to give you a kind of worst case scenario. It has massive potential and the patents hold it tight. Lets hope we get through this durability nonsense and move to human testing as before. Been a ridiculous delay these last two to three years. Get this job moving!!!

It won’t be that long imo

The importance of tolerability is significant for clearing the durability stage that was poorly performed previously as per setup on such low doses. It means that with the new formulation they are clear to use at those levels :)
That is Fantastic news for next stage. The drug is not toxic at these much higher levels. Great for disease effectiveness against IPF. This is very very good.

Durability from Anne’s choice was test at absolute minimum levels in rats. Rats don’t relate to Humans much and therefore are actually not very good for getting reliable results due to differences to Humans. All NFX need is to secure this Durability data stage to move to next stages for negotiations and secure either investment or partnerships which could either develop them into a company to move forward or sell.
So pump it in much higher get the data and boom we are moving forward. Won’t be long. Very confident indeed.

Yea I do know what is required by the way! ;)

Oh you know it’s a few months lol ?

August Durability testing starts. Won’t need to worry about much else. Peer reviewed in September to discuss and promote the huge marketing of NXP002 with orphan status and combined SOC with current products. The value of current products market was highlighted once again and NXP002 is known to enhance those products plus enhance patent protection longevity.
Won’t need to wait long imo to see a very significant rise in value. SP went from 1.85p March 2019 to 11p prior NXP001 data in May 2019. It did this before results.
I’m not staring prior performance proves future performance but basic rules apply with investor sentiment and positioning.
Current MCAP is very silly and now stability is here along with the correct history in knowledge.
Lets see!

Another
“NFTs
Posted in: NFX
Posts: 81
Price: 0.50
No Opinion
RE: Great tick up today22 Jul 2022 18:00
A dan good day for once!”. ;)

What’s you holding Blood? Or you here for our good health. So kind

A dan good day for once!

4th September they will present at the exhibition the full data package that includes the durability.
Motoring on.

Posts: 76
Price: 0.47
No Opinion
RE: Position building31 May 2022 17:23
“The global anti-inflammatory drugs market size stood at USD 93.88 billion in 2019 and is projected to reach USD 191.42 billion by 2027, exhibiting a CAGR of 9.3% during the forecast period.”

As mentioned it’s the Inflammation that is going to blow the doors off!

Really great to see this. Sends a solid support message of news will be coming on a very well tested drug. Glad to see. Well done BOD

Non executives and the knowledge of the ex CO about is enough for now and saves a packet.

So to backup against these wild weak baseless negative opinions from apparently holders. I will try place some facts on NXP002

“Further in vivo studies evaluated the pharmacodynamics of NXP002 when delivered by nebulisation. This study showed that inhaled NXP002 could dose-dependently regulate the production of inflammation and fibrosis-relevant cell mediators in response to a lipopolysaccharide ("LPS") challenge.”

Duration invivo test
“The duration of action of a drug is the length of time that particular drug is effective. Duration of action is a function of several parameters including plasma half-life, the time to equilibrate between plasma and target compartments, and the off rate of the drug from its biological target.”

So to try and put some weight behind the inconclusive CRO data I will try explain.

Tranilast is a very well known drug since invented n 1982 and owned by Kissei Pharmaceutical Japan who hold many many years of data and have had a few other companies take it on for other directions.

It’s a drug that is known to be durable and the toxicity is well known.

The cocrystal route Nuformix have taken is as most know to solve the toxicity issue by reducing the amount required to treat patients.

The previous in rodent data that NXP002 did proved that the drug is delivered via nebuliser.
That’s the main one. Can they get it to the target required. We did.

Durability as many know is what was the amount that then went into the blood and organs etc. This is where the CRO has come back with inconclusive data meaning they couldn’t get a result from the test to make any conclusions.
So something went wrong on this small test because we already know the drug is in the lungs from last invivo test and we know Tranilast is absorbed to the body from all the years of data. It’s even a topical cream for skin disorders.
So they need to test again. From Anne’s statements it was about using lowest dose possible to limit toxicity so this being done on small rodent tests could be risky as the variability of these tests is well known risk of using invivo testing methods on non human species. But it’s obviously safer than human Guinea pigs.

So perhaps it’s easy to have judged the test protocols slightly wrong. That’s then not a big issue.

Then read Riddels statement on the operational update. Looks mighty confident to me on the main line!
Just my opinion.

Wild speculation with statements like that.
Read Riddle's note!!

He wanted out and opened the door to move to his other work. He was never here for what he did and was not wanting the front of house pressure.

We will see and come back to your post soon…. We can then discuss lol

Certainly from a management side this looks a terrible investment and the management over last couple years have inflamed the situation. I certainly believe that none of the management knowingly intended to its just they had a direction but very little loyalty to the company apart from living off a salary that they could get elsewhere and pass the hard work onto someone else.
The two that have most to lose now apart from current share holders are Dan and Joanne.
My main dissatisfaction has been the lack of knowledge and voice from Joanne who hides away from pushing any management decisions onto the board. Truly mind blowing how one the most influential founders who has a large handle on the products has not stopped the new joiners taking these drastic directions when tbh these were all set back in 2018 and just needed sending down the line.
Dan has forged another income and future and had no voice in past two years until recently when they brought him in as a consultant.
Right now the appearance of no clear leadership is damaging but at this price in MCAP with cash to continue NXP002 to next data which opens up negotiations and also taking NXP004 onto discussions and patents pending especially NXP002 later this year. Positive data will flip this into a viable place to take on.
So I can understand non executives just letting the data perhaps come and do the talking. As this will lead onto firm territory.
All to easy to bash with wild statements but that’s because it looks terrible thanks to Riddel walking and leaving in such a way.
My guess he was trying to force a certain person back but he may not have the opportunity currently due to other commitments. This does not mean this is bad just there are other ways to negotiate this current hiatus in management.

So basically lots of noisy people trying there luck here in driving negativity in a market that is naturally in a downtrend. This though is so undervalued that when that dot finally drops with a positive update this will reverse some.
For now ignore hold wait ;)….. or sell go and shut up if neither then you have alternative motives.

I see Dr Dan Gooding has posted on his profile in last day of being an official consultant on Nuformix!!!

;)

I do do what I want.

I also have invested here. You don’t Mmmmmm strange????? How many posts. Is this your only non investment that you spend your time invested?
Very odd….
There is only one type that does that. Enough time waisted by me. Never feed a troll as they always win because pigs swim in ….