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Wyndrum
Do you admin a telegram group by any chance ;)
Connected manipulation collusion is rife across these platforms in group attacks.
Concerted effort to try create agenda to trash SP and oust AS.
Anyone promoting this idea is either doing it to cause more damage or has no idea how stupid that idea is right now with this company on the cusp of huge negotiation period later this year.
Don’t bite the agenda these rats are spreading.
It will hurt AVACTA taking out the CEO.
CFO can be moved aS they have been silly in failing to protect us better from this nonsense.
What a pack of lies.
The level of effort is staggering.
You sold and want to buy cheaper and will continue to push negative agenda until you buy on probably a news significant day or when the trend breaks out.
Otherwise you are just as suspected a simple scamming trader playing the boards as they do to a high level.
Sad existence indeed
One simple question then!
If you are as you say not as enthusiastic as some why would you invest or stay invested if you are not that enthusiastic as PI’s we generally invest in stocks we are enthusiastic about to the extent we invest our hard earned money.
Now the the other option is you could be a trader who just buys and sells to TA or guess work but spend a lot of time trying to manipulate social media to appease yourself in doing the right thing and pathetically trying to change agenda to suit your positions.
Mmm 🤔
Let’s remember the reason for holding is that they now have better results than they ever wished for.
They are cashed up so they can negotiate strongly.
They will deliver when the data of the 2 weekly studies are complete.
That the IP for much larger potential targets are being carefully put together as we speak.
That buyers are there but they do not want to negotiate any terms until the larger picture is displayed for all to see.
That lines like 3996 in early stages are worth many multiples more!!!
That even as we speak similar deals of 2bil would be on current knowledge but as the up and coming data and IP in near term this year will potentially mean deals closer to many more multiples of 2bil become likely.
These are reasons to hold onto the shares as these potentials unfold.
It’s pointless discussing with agenda ridden posts.
The facts are Dr Tap stated any improvement to standard Dox will become the future go to for Dox.
AVA6k is not only an improvement it’s blown expectations and become a potential cancer eliminating drug not just to prolong life.
It’s massively less toxic fact.
Therefore excluding the proof of Precision which again is now 100% proven.
AVA6K will become the go to for Dox chemo therapy.
The values are huge now that precision is proven to be a warhead delivery system.
What we need is to show it in the two week dosing arm to really show potentials.
You cannot argue it’s proven as they have told you it is proven.
If you cannot understand this fact then you will not listen to the fact that any FAP targeted drug will be weaponised.
The list of these drugs on and off patent is huge.
They outweigh the proof of concept drug AVA6k (Dox) by 100’s of times in 10’s of billions in annual sales.
The company that acquired Dox can out license PreCison for particular drugs on a royalty basis.
Not only can they chose but also sell the tech on many 10’s of drugs now.
It’s a race against time to lock in as much value as you can and AVACTA are not going to do that. It will always be a major.
This game starts from here and already is happening behind the scenes but before any real figure can be placed here that BP needs to say why it’s offering that price to its shareholders and BOD.
Upon which if it’s too low then a bidding war between BP will start.
I doubt anyone will get this whole entity for less then 10 bil. It’s worth that many times over on certain drugs alone.
Absolutely
You can see all the short term traders are the ones posting the frustration and nonsense across all platforms.
Ignore and watch the team deliver an outstanding result over this coming future.
Just tiresome listening to the little impatient children.
What we can see from the dosing is that lower dosing has near on no bad effects at around cohort 3,4,5 areas.
Like any disease cells regrow so if you hit them quicker then they cannot grow back fast enough so reversing the process of cell growth.
Now a 69yr old patient has been I believe on cohort 3 since Feb 23 thereabouts on 3 wk dosing which as we know is not quick enough to get that reverse action working properly.
Therefore it is truly remarkable that it’s also working on these 3 wk dosing intervals so 2 wk dosing is going to be one hell of an improvement in action.
With a 45min half life then we know that dosing even quicker will be possible imo. Who knows weekly / every other day etc at lower dosing will obliterate tumours. We have seen precision hits selectively FAP and delivers Dox efficacy splendidly.
You are looking at the holy grail of chemo precision right now and upon the 2 wk data release I think that will be enough to get our first Major to come fwd with an offer.
With 3996 data due out also and IP protection being primary then the multi billion £ assets will come alive.
It’s a very big year ahead for Avacta and those loyal investors here.
Ignore the city paid spivs playing the spreadet CFD game. They know nothing. Their luck 🍀 is nearly up ;)
I had been warning that this is most likely outcome since 2022 but always got shot down instantly by a few here who continued to try buy themselves out.
This company showed no success in 22 and it should have at that point. US flop EU flop. Small contract wins flop even a so called NZ air deal which imo was done on a special rate to try hide facts.
TB is a flop that cost shareholders their money which he simply didn’t care. The only thing he wanted was to try get his HIS baby afloat at any cost. Now sells out to Chinese. I don’t think that’s a surprise either imo and all been played out to escape after he realised taping the UK market no longer works like he hoped. Bad advice all round here.
“ NFTs
Posted in: EISB
Posts: 458
Price: 1.025
No Opinion
You were warned25 Jan 2024 12:14
I explained that the business plan is awful and it still is until they drop prices lower than fever and grab volume. Tony’s brand is good but the direction of exclusivity is the problem. They need to drop expectations and think about surviving. Unfortunately that imo won’t happen.
“NFTs
Posted in: EISB
Posts: 386
Price: 1.225
No Opinion
Few million required3 May 2023 15:25
The issue is funding and nothing to do with any poster stating the obvious. If people are trying to average down be prepared as 2 million now will be more than 50% dilution of the SP.
I am surprised that management have sat on their backsides to raise capital so late here in this market. That’s exactly what happens to others that shut the doors. Too little too late springs to mind here. Protect what you got as managers are not looking out for you here they are looking out for their pet project which was supposed to find cash easy here over on the UK main market!!! Oooops”
It was finished in 2022! They have kept the shocking truth being said but the facts on figures and reality were there in black and white but the management were only in the UK market to try last chance saloon to extract cash to fill Burts personal dreams but he was a dreamer and too obstinate to realise his dream was just not possible in large form.
It’s terrible how a NZ company can list and hide facts to keep taking money from UK investors. It won’t be properly investigated to hold BOD to account and the Chinese will ensure Burt gets payback imo.
Shocking and anyone with considerable cash in here should form a group to go after BOD to ensure they also pay the price properly for what they have knowingly done and hidden over this last period to try escape.
For example
https://www.astellas.com/en/system/files/news/2020-02/20200220_en_1.pdf
Too many newbie’s trying to sound like they have a clue in what is going on here.
Worth checking out the below to realise how close they are to getting targeted therapy approved for certain indications.
precision conjugates can get approved quicker than new drugs. This is because precision conjugates are often based on existing drugs that have already been approved for use. This means that the safety and efficacy of the drug has already been established, and the focus of the approval process can be on the new delivery system.
In addition, precision conjugates are often designed to target specific diseases or conditions. This can make them more effective than traditional drugs, which may have a broader range of side effects. As a result, precision conjugates may be approved for use in specific patient populations, which can reduce the time it takes to get them to market.
Here are some examples of precision conjugates that have been approved quicker than new drugs:
* **Brentuximab vedotin (Adcetris)**: This precision conjugate was approved by the FDA in 2011 for the treatment of Hodgkin lymphoma and systemic anaplastic large cell lymphoma. It was approved based on a clinical trial that showed that it was more effective than the standard treatment at the time.
* **Trastuzumab emtansine (Kadcyla)**: This precision conjugate was approved by the FDA in 2013 for the treatment of HER2-positive breast cancer. It was approved based on a clinical trial that showed that it was more effective than the standard treatment at the time.
* **Enfortumab vedotin (Padcev)**: This precision conjugate was approved by the FDA in 2019 for the treatment of urothelial cancer. It was approved based on a clinical trial that showed that it was more effective than the standard treatment at the time.
Overall, precision conjugates are a promising new approach to drug delivery. They have the potential to improve the efficacy and reduce the side effects of drugs, which could lead to better outcomes for patients.
sorry for those losing money but i made my opinion very clear here for last year and a bit. they had failed to change tact to higher volume lower margins with a cheaper product outlook. this cottage style mantra of ultra premium around the world without a lot to **** in was a dreadful business plan. burt has been at this for nearly 10 years prior to coming to uk market to milk it. problem is he was 10 years too late and uk market now doesn’t play ball like it did.
you cannot say you will possible become profitable in a year or so when your whole business plan revolves around investment for growth. it will never make a profit on this current business plan and i said that ages ago.
it was doomed unfortunately to ever succeed when it started to lose mcap it couldn’t raise to carry on. i hasten to say covid shipping prices did kill it quicker but it was going to die.
fevertree cheaper and frankly nicer!
aberdeenman again finds another howler of a company lol 😂
It always been coming but it really is now a matter of waiting till that first major goes for a bid and on that bid will come the starting gun for a massive bidding war.
This cheap solid tech is the way to go for a generation or two with all the other warheads they will attach,
Anything less then 10 bil and you will be a loser ;)
you can tell it’s about to lift off as the city have their usual posters working overtime.
as absurd that that seems it’s obviously true here.
really sad people to try ear money spamming message boards with constant ****e
I’ve a few 100 thousand votes which is only a decimal of a percentage here and I’ve had a huge hit in my financial position but I absolutely strongly believe that any of this money raised now is going to deliver a huge return. Obviously I’d loved to have hindsight and sold and bought back down here to get way more shares and be laughing but I didn’t.
I’m 100% certain on outcome here and 100% certain he can deliver that for us as shareholders.
I also wished it had been placed higher but it hasn’t. I can deal with that if confidence in the company and product.
This has everything it needs but a sale to a major. That will be what comes sooner than expected.
Lucky for anyone who can load up at these levels.
No Redshoes 👞
That’s not why they have only done 10%. And yes you were saying they had plenty of funds to last.
Simply if they tried more the price would been a lot lower and the risk for those who will be dumping those shares over coming months will struggle.
Every year now this share has a large holding being dumped. When that finishes they will then raise the next tranche and so on. Sort of like Lanstead but just more conventional and easier.