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S 25 °C or 37 °C and the cited document 1 is 5 °C). Since these results cannot be said to be clearly different from each other, the allegation that the two are different from each other is groundless. Moreover, a concrete ground for supporting the applicant's allegation (experimental results, etc.) is not presented. Therefore, the aforementioned allegation of the applicant is unacceptable.
At present, no reasons for refusal are found with respect to the inventions according
to Claims ( 1-10,13-21 ) at present at this point.
1.JP 2006-306765A
------------------------------------------------------------------------
The applicant who is dissatisfied with the examiner's decision, may file a request
for a trial against examiner's decision of refusal to the Commissioner of the Japan
Patent Office within three months (where overseas resident, within four months) from
the date when the copy of the examiner's decision has been served (refer
As I mentioned this has no value if this gets refused again! A lot hangs on them getting this. Looks like bad blood in Japan from Kissie pulling them up to protect their drug.
“Notice of Transfer of a Case for Reconsideration by Examiners before Appeal
Proceedings
Reiwa 5(2023) September 14
Commissioner of the Patent Office
Number of the request/demand for appeal/trial: Appeal 2023 - 12306
(Application number) : (Japanese Patent Application No. 2020-555115)
Demandant: **** mix Technologies Limited
Representative patent attorney: ASAMURA PATENT OFFICE
Since there was correction about a Description, a scope of the claim, or Drawings
simultaneously with the request/demand for appeal/trial, and an examiner is made to
examine in accordance with the provisions of Article 162 of the Patent Act
(reconsideration by examiners before appeal proceedings), we announce you this the
case of appeal against the examiner's decision of refusal.
Specialist for Formality Examination ODA, Naomi T664”
“Decision of Refusal
Application number: Japanese Patent Application No. 2020-555115
Date of Drafting: Reiwa 5(2023) March 9
Patent examiner: TSUCHIHASHI, Keisuke 3839 4H00
Title of the invention:Tranilast salts and pharmaceutical use thereof
Applicant: **** mix Technologies Limited
Representative: ASAMURA PATENT OFFICE
This application should be refused for the reason 1,2 mentioned in the Notice of
Reasons for Refusal dated 10/28/Reiwa 4. Although the written opinion and the written
amendment have been examined, no basis sufficient to overthrow the previously given
reason(s) for refusal has been found.
Remarks
Regarding Reasons 1 and 2 (Article 29 (1) (I) and Article 36 (2) (I) of the Patent
Act) 3
- Claim 11,12
- Cited Document, etc. 1
- Remarks
Reasons 1 and 2 on the basis of the cited document 1 are as pointed out in the
previous notification of reasons for refusal. In the written opinion, "A 1:1
Tranilast potassium hydrate salt of the inventions according to Claims 11 and 12 of
the present application" While high water solubility and high solubility stability
are exhibited (Examples 13 and 14), the crystals of Comparative Example 1 described
in Table 7 of Cited Document 5 and the crystals of Comparative Examples 14 and 15
described in Table 9 are precipitated as sparingly soluble salts (crystals) in an
aqueous solution. Therefore, the characteristics of the two are different from each
other, and it is reasonable to understand that the salt described as a comparative
example in Cited Document 1 is characterized by the specific powder X-ray diffraction
pattern, and that it is not a 1:1 Tranilast potassium monohydrate salt. ". However,
working Examples 13 and 14 in the description of the present application and Tables 7
and 9 in Cited Document 1 differ in terms of the dissolving conditions, and in particular, in the case of Cited document 1, the temperature of the aqueous solution is considerably lower (the present
AstraZeneca have been in the background for well over a year. They need this. The problem is as one goes forward they need to deliver a bid that actually values the asset correctly immaterial to what silly MCAP we currently are.
What they need though is to prove to their shareholders why they have to stump up 20 billion etc. This is the crux they face. We know the platform is going to continue to move down the line and grow. AS and his team want to do that but the Majors will have their own IP and returns to protect along with the never ending requirement to feed their continued growth and dividends to investors, so they seek out the next future drugs.
AVACTA threatens many Majors assets and the preCison platform is overwhelmingly showing the world its abilities to enhance proven valuable drugs. Taking them from those companies.
With things now speeding up significantly with basically Phase 2 now in progress to start next year we are in the firing line for aggressive approaches.
The main point though is they need to gauge their bid right!! As others will come in also causing a bidding war. It’s almost like the Majors want to keep their heads stuck in the sand because they cannot face messing up the approach to a business that if not squired could wipe out many billions of their current assets and revenues.
Game on
This was one of the desperate last chances they had. Pennies is what they got!
Cannot even afford pennies to maintain the patent. As mentioned not even close to any deal. NXP004 not worth the paper it’s written on and cannot even flog the patent.
NXP002 requires more tests and they haven’t any money.
One more placing and then it’s lights out. Desperately trying to claw something back. Remember Dans consulting firm he sold!! Hence NXP001 money got sold away without the company getting the money in underhanded way imo.
The smoke and mirrors continues that they cannot even call this payment significant and the last NXP001 payment which was significant of 50k lol. When they have no money even 5k would be significant here now lol lol lol lol lol. S H * T sandwich classic DG style.
Plenty here trapped licking wounds desperate to try claw a little loss back.
“ The time it takes for a revised patent to be processed can vary depending on several factors, such as the complexity of the revisions and the workload of the patent office handling the application. On average, it can take anywhere from several months to a few years for a revised patent to be processed. It is best to consult with a patent attorney or the patent office itself for more accurate information regarding your specific situation.”
It’s going to be sometime still waiting here. Money is only going out and there is only one way to secure the future for another year!!!
Bills salaries and accountancy broker meetings travel costs.
Ready for insertion as explained
How many times have we heard this about how CLN’s initially sound like a great possibility but the truth is it was the only option of debt raising it will end in the usual mess.
I’ll tell you why. They are three years away minimum to getting into possible break even here.
What will happen is initial LTH will try buy in to reduce their average. Once that happens and new investors see the CLN’s there and the fact the accounts show terrible profit to loss margins and the fact it’s just going slower than predicted to gain a sustainable business. They realise in 1 year another raise is required as the loan notes get to point of conversion the SP will collapse. This cloud will hang over causing issues. Watch and see.
Looks like Lanstead are really struggling to off load them and I really do wander if it was a nominee account for Lanstead that took this last placing shares.
One thing with this company is that they have always hidden the truth and try to hide things.
No hiding that a big placing is coming at the AGM. They need to vote to get any cash here as the MCAP is so pitiful and it’s going to get a lot worse.
Oh look there is one those lovely A trades that Lanstead get specially just under the buy price as I was talking about the other day.
Wait till that selling support goes. When I mean supportIneanthe fact that they get special conditions to maximise profit and NFX don’t mind as they have milked investors too for the few extra pennies.
Watch that 0.2 support disappear when no deal comes and AGM approaches in what 7 so weeks time!!!
Not at all.
I’ll be smiling at that soon!!
Keep buying fill your boots. AGM fast approaching and they cannot raise without a vote otherwise you get just a few grand like last time.
If you think £70,000 was raised just as a little top up then think about it a little harder.
Looks like a few bought in and got trapped on the hype.
Especially those that bashed it for what it is.
Fomo here is definitely not something to be concerned about as there is simply nothing to fear of missing out.
A cheap quick test of drop on some lung tissue, some failed durability data costing millions and ummm some slightly less white powder on NXP004 and NXP001 sold off for 50k
Only fear here is the next dilution on raise incoming Sept
See the A trade there for 300,000 shares.
Those are the MM’s under the agreements with Lanstead to flog at just shy of the buy price. Nobody else ever gets such treatment and it’s been this since Dec 21 that has propped up the SP from dropping to 0.1p.
Those trades will disappear this month and that will turn off the extended manipulation and support to try drag out as much cash as possible. The upsides were NFX management also benefited from this but now that’s coming to the end. First Tranche of the 20 month agreement started in Dec 21 as per the RNS!
The only time anyone else gets close to these market trade values and spread is when you bed your ISA and the Brokers will get the MM’s to sell and buy the stock near the bottom of the spread within £25 to £100 for the costs.
So if you need proof that’s your proof of manipulation that’s possible.
This is exactly what Lanstead have done and now that is about to turn off.
Watch as the SP now crashes later part of this month as the offloading support disappears.
Of course some will say it’s great but believe me nobody wants to add here until funding is sorted. Of course BOD inform you they have loads of cash and at no point need to raise soon lol!!!! But they don’t tell you the £100,000’s spent on those latest test. The more expensive tests! Fill your boots ready.
If you hadn’t realised I’m talking about the last test they did after the failed rat testing on durability duration of action etc
They dumped stand-alone NXP002 and dragged out SOC NXP002 to do human lung testing like they did previously before the bafoons took control after wimpy walked out in a huff causing it all to go to rats!!!
That latest test was done after March after those accounts and the human lung tissue!!!!! Which is what I am talking about and for LTH you should understand this basics, they spent £100,000’s of their last pennies to get something otherwise shut the door game over.!!!
Jeezzz
Soup
It costs much more than rats and since they wasted 1.5mil on rat dat that failed they had only a tiny amount to try a quick sliver of human lung tissue at Newcastle to gain some basic pre clinical data. That testing was done after those accounts and the very basic cost will have been over 300,000 hence the desperate £70,000 placing to get them to AGM in Sept.
The BOD are not going to openly tell the market they need cash now are they. Anyone thinking they are being honest and strait faced is deserving of the next slap by the market.
Won’t be long.
Guess next month we will get another webinar with the sales team and Dan yapping and spewing out more regurgitated info. How wonderful all is and so much interest etc etc.
Fact is nobody has come fwd with any approach in monetary terms and this preclinical news so far is not groundbreaking or new just reinforces what was know in 2020. Yet all of a sudden pharmaceuticals are coming surging in to give this company 80 mil deal or 20 mil upfront lol 10 x what’s is worth!
Rather than buying a position of interest and TO of its so wonderful. Yet nothing and AGM is approaching. Money required as always!!! 10% isn’t going to keep the lights on so you know what that means a big FAT VOTE of go bankrupt or accept a lovely placing of such promises Mmmmm cannot wait for another, yum yum yum thank you so much NFX virtual team.