RE: SARS COV 2 does not induce IFN secretion23 Apr 2020 07:15
Jack-allis - Great find, noted part of the conclusion to one of these reports, University of Texas:
Overall, our results indicate that SARS-CoV-2 has a much higher sensitivity to type I IFN
182 than the previously emergent SARS-CoV. This augmented type I IFN sensitivity is likely due to
183 changes in viral proteins between the two epidemic CoV strains. Moving forward, these data
184 could provide important insights for both the treatment of SARS-CoV-2 as well as developing
185 novel animal models of disease. In this ongoing outbreak, the results also highlight a distinction
186 between the highly related viruses and suggest insights from SARS-CoV must be verified for
187 SARS-CoV-2 infection and disease.