Member Info for Leggster

Really good to see the committee dates

Have read through these all arep in line with my expectations, felt the responses to give some further comfort on things we may assume or have come to assume. It was pleasing that SAR have seen all returned 737 data and to get confirmation that any news on 1801 will be upon the point of HREC approval with no interim news on the CTN (I had assumed we would get an announcement after the CTN step so for me this was reassuring) also good to see confidence in the manufacturing processes. MHRA performance seems really shoddy and feels like no root cause at SAR for the delays. GLA

Well the wait continues, it will be interesting to see which news drops first, I personally think 737 first then trial but suspect both will be soon. Then once in trial I expect an 1801 deal before the completion of the trial but then expect some movement on 1802 with hopefully a cash runway then available to go deeper on 1802 than 1801. GLA

Yep some inputs are very predictable, me for example, I am nearly always positive (the historic Friday FLT3 RNS was for me very disappointing and spoilt my positivity) therefore I am looking for a red dot sometime soon, SAR like a Thursday RNS let's hope with some good news. GLA

Thanks HBD, on 737 I tend to think the majority of negotiation will have happened before the return from GSK with Heads of Terms agreed based on varying possible outcomes from the results, I personally think therefore this will get resolved at pace. Very positive on prospects here.

Nice movement in the new tax year but I don't find that surprising 737 news is coming and we should hear on the CTN imminently. The extract below is from the aus.gov site, even allowing for some beauracratic delay and payments to clear and be matched the decision for good or bad should be with us. If no news Tuesday I would think that could well be some speculative buying on the fact that the ctn outcome is literally about to drop

'The target time to process online CTNs is 5-7 working days; however we endeavour to process the notification as soon as possible. Please note that this timeframe does not include the time taken for TGA finance to match the payment (if required) to your submission.'

GLA

Yes new tax year, news due on two fronts that will move the price, then I then think a deal on 1801 during or at the end of the trial. Though lower payments at this point for me this is a sound strategy to allow sufficient funding without dilution to take 1802 to later stages before licensing, giving a greater long term return to shareholders. The unknown of course is 737 and what a new deal looks like as this could be the funding source allowing SAR to go deeper on 1801 before licensing. I do also wonder if SAR may spend sometime on FLT3 and resolving its solubility issues. Exciting days currently and very much on the cusp in my opinion of a material permanent rerate hopefully though up on good news. GLA

Potnak, there is though an online site of all approved trials in Aus/NZ, once approved our trial will be added, with the time difference this will probably be whilst our market is shut. They may well have material non public information policies but could equally take a view that its the responsibility of the applicant to manage any implications of news release. One of the earlier comments around an out of hours RNS seems to me to be the likely outcome as I would imagine the Aus authorities have not designed their processes for UK biotechs. Anyway in Q2 now so hopefully we find out one way or the other shortly. GLA

I have never before been invested in a share where there is a significant event that will move the SP being triggered by events in Australia. Does anyone have prior experience of this for example if the CTN is granted (or rejected) early on a Monday in Aus then our friends at SAR could be asleep and may not therefore be able to press the go button on an RNS before markets open. How does this play out is trading suspended until an RNS is released?

Sorry to hear of your loss, my condolences to you and your family

Is anyone else sadly like myself checking the ANZCTR clinical trials sites to see if we get a green light, impatience is something I really need to try and surpress, lol and GLA

Read through the document shows a real appetite to grab a slice of the Biotech pie, unlike our own regulators currently

Will this be a news week, will FOMO start to come into play, the new tax year is coming and I suspect the MMs will want shares to meet demand once PIs can access a new annual allowance. Lots of reasons to be watching your investments. GLA

Looking forward to tomorrow, will be interesting to see if the BOD have managed to line up any other news that can be shared. Will join the investor meet with interest to hear the tone of the presentation and fingers crossed for some forward looking statements. GLA

Very young, rest in peace

Pleased to see clarification this morning on rhe direction for 1801. This gives a clear message on the way forward and gives me no concerns. As others have said 737 will be resolved shortly and the BOD have not been sitting on their hands with 1801. I'm happy with the pivot to an Australian plan, the pivot is not weakness or failure its good proactive management of events as they unfurl. GLA

Yes I think news is imminent and with many more actors in play the chance of leaks is much higher.

Agreed, but I believe the waiting is coming to an end, in the coming months we either move forward into trails and deals are we fail to gain approval to go into trials and fail to sign deals one way or another we will know relatively soon GLA

We all invest for our own reasons and have our own views and strategies. I did not sell at the peaks, with hindsight it would have been great to sell and buy back lower, but I do not overly regret holding I still believe this is a fantastic opportunity in the high risk high reward bracket, we have three potential blockbusters all in strong sectors of interest and all in my opinion have the potential to deliver life changing rewards. 737 will hopefully deliver a further re enforcement to our cash reserves and value to shareholders through a rise in SP or one time dividend. Then 1801 and 1802 can deliver real additional value. In my own opinion Tim and John have delivered great value for our investment, there was no dilution after consolidation and I choose to believe this was because they do not believe it is required, they did not raise to maximise the return to investors including the HNWIs who will definately have asked about further funding rounds before investing. For me this is still an exciting stock, I look forward to the red dots as I am convinced that we will see deals and significant rewards for patience I truly believe we are in the home straight, GLA

Thursdays are often news days, my own preference for the current situation is for a buyout of 737. With the proceeds resulting in a special dividend but enough cash retained to increase the cash runway and fund 1802 into trials. GLA for the coming days/weeks