RE: Bottom line3 Jun 2020 14:52
Pingu, nice to see some science, maths and facts coming back to the board :-)
I did some really rough back of the napkin maths a while ago to see if hemo was undervalued when it was like 2p, some of its guesstimation some of its based on a very quick google.
I picked the Hu-PHEC pipeline because it looked close to stage 1 clinical trials, and now looks like will be starting in the next few months.
Considering Hemogenx approach and lets just pick ONE disease leukaemia (This has wider applications)
Lets narrow it down to JUST the UK where over 2,000 people in the UK are in need of a bone marrow or stem cell transplant every year.
That number would be much higher if bone marrow transplant was a first line treatment, because of complications its not the first line.
Now look at the cost which is about £200k per patient. So there is maybe £400mil being spent on bone marrow transplants in the UK in a year? Now in terms of royalties, lets assume something like Hemos Hu-PHEC became the norm in this scenario your talking what? No idea what the % would be, lets call it 10% for easy maths, £40m per year for licencing their treatment thats about to go into Phase 1? When the market cap today is only £28M
Now consider: I picked UK because its much much smaller than the US so the numbers of treatments here is tiny in comparison.
I picked 2k people require the treatment AT PRESENT, in reality because the patients own cells are used the risk from rejection or complications which limit this as a treatment option disappear, so this moves from almost a last option to a first line option.
With what 10k+ people diagnosed a year with leukaemia the market gets alot bigger.
That said, I am not a scientist or a doctor, just a keyboard warrior with some money to invest. My first aim is to protect my investment which means investing where the risk is low. Based on just ONE single strand of work that Hemo are working on the potential market in JUST the uk is more than the current paper value of Hemo PER YEAR.
Include the USA or CDX or bring in Lupus treatments or perhaps some Covid work............