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an immune response to check growth ... wow !

pancreatic

interesting tweet ....

Ruth Cadbury MP
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@RuthCadbury
3h3 hours ago
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I'm proud to pledge my support for @PancreaticCanUK campaign to get treatment within 20 days for people with pancreatic cancer. 1 in 4 people with pancreatic cancer will die within a month of being diagnosed, so it's vital that we

but it has to be based on a technology ........ to develop into, this is what we plan to do ...

then give it a name ... Modi-3

otherwise i could apply . and declare This is what i intend to achieve but i don't know how ..

? 7.92 was a sell .......... 8p was a buy you maybe getting confused by this tiny differences of 1/100 of a 1p

Should just listen again at 24 mins in ......... https://youtu.be/CXyPYib5JWc

cheer up ...... you have just had the science presented as to how that Modi3 can be achieved

these delays are allowing others to catch up ....... Really ? Scancells just leaped another 10 years ahead of every party out there

The Modi-2 peptide family is the subject of new intellectual property applications with a view to extend the Company's dominant patent position in relation to post-translational modifications of cellular proteins and their application in the treatment of cancer.

show me any research that has the potential to tackle near 90% of the cancer market with an injection ?

manufacturing takes about a year as the process is proved up with toxicology etc etc
you have seen it with Modi1 and scib1

every one including the market have just not got there heads around this dual attack on cancer from Citrullinated and homocitrulline

Modi2 ... is your Mod3 its the same program hence i mentioned the patents causing the delay possibly with the Grand challenge

this homocitrulline patent is mind blowing in value, i think Bermuda would agree 100% on this, that if they have cracked the code to break open cold cancers .... Lindy's word Cure in the majority of patients now is gaining credibility

it really is that good ..

You guys moan about raising cash
then you moan about a 3rd party investing SCIB2
now the Grand Challenge ref brexit ? what ? how would that impact research ? even with BioNtech ? or ISA
you moan about Ichor than you moan about the time to change to nanovesicle ..
what is the Mindset of folks today ?

every post seems to be presented as a moan ..

you all seem to be talking to each other, any one reading this BB would not have a clue, what a CH means .. blah blah

are you all getting lazy .. or are we switching to morse ?

https://www.scancell.co.uk/file-manager/PDFs/autophagy-citrullination-and-cancer-2016.pdf

"""Thus, autophagy induced in the presence of interferons
would allow presentation of peptides on newly synthesized
MHC-II molecules. """"

separate out the statement

CD4+ T-cells are the orchestrators of the immune response and, when activated
within a tumour, release interferons (IFNs) that can reverse the immunosuppressive
environment

(and the T cells)

and can act directly to upregulate MHC expression on antigen
presenting cells (APCs), and stimulate the release of pro-inflammatory chemokines
to promote further the immune response

by that way that is from the hardman Report

CD4+ T-cells are the orchestrators of the immune response and, when activated
within a tumour, release interferons (IFNs) that can reverse the immunosuppressive
environment and can act directly to upregulate MHC expression on antigen
presenting cells (APCs), and stimulate the release of pro-inflammatory chemokines
to promote further the immune response. The autophagy process activates a
cascade of events that ultimately presents citrullinated peptides on MHC class II
molecules, which will trigger the immune response via CD4+ T-cells.

its a feed back loop ......... clonal expansion,

the key is the adjuvant ... that turns the T cell to pro inflammatory . this delay of the modi1 vaccine to facilitate amplivant incorporation from ISA is critical to the process because it means we get the TH1 t cells

so why folks are moaning about the delay .. the value of that is off the charts

1, correct
2. plus the T cell will pass the info of the MHC class 2 epitope

this is why 5 on hardmans list looked so strange it would mean the APC had direct contact to the cancer cells

CD4+ T-cells are the orchestrators of the immune response and, when activated
within a tumour, release interferons (IFNs) that can reverse the immunosuppressive
environment and can act directly to upregulate MHC expression on antigen
presenting cells (APCs), and stimulate the release of pro-inflammatory chemokines
to promote further the immune response. The autophagy process activates a
cascade of events that ultimately presents citrullinated peptides on MHC class II
molecules, which will trigger the immune response via CD4+ T-cells.

once moditope has activated the T cells and they travel into the tumour they can pass on to other APC's to assist (upregulate)

i have emailed Richard, i assume APC in 5 should have been T cell ..

if you look at the diagram, No secondary APC any where near the cancer cell

check number 5 crumbs

Trying to over turn the patent ...

Off now .. ATB

May be exploited ?

not that a natural response will self generate

you didn't miss it ... as Konar already picked up the text .. stop giving this BB so much Bull ..

""This is no offence to noise, but if that simplicity floats your boat why are you trying to present your self as technical ? because you just seem to want to cause conflict rather than any sensible discussion""

spot on ...